Results 11 to 20 of about 126,008 (360)

Elastase inhibition by natural flavonoids: mechanistic insights and potential therapeutic applications [PDF]

Frontiers in Nutrition
Overproduction of elastase plays an important role in the progression of inflammatory diseases. In this study, we compared the inhibitory effects of structurally similar bioactive flavonoids (quercetin, hyperoside, luteolin, and luteoloside) on elastase ...
Lihao Lin, Hongliu Yao, Jinfeng Fu, Wenhui Zhang, Yongxue Li, Yan Wang, Haoyu Shen, Jingang Mo, Yi Guan   +8 more
doaj   +2 more sources

Previous COVID-19 infection significantly reduces elastase levels in newly diagnosed pulmonary tuberculosis patients [PDF]

Frontiers in Immunology
IntroductionTuberculosis (TB) is considered a risk factor for severe COVID-19 disease and the quality of life of patients co-infected with COVID-19 and TB is significantly impacted due to the nature of these diseases.
Nancy Hilda Joseph, Alangudi Palaniappan Natarajan, Saravanan Natarajan, Chinnaiyan Ponnuraja, Madeshwaran A, Gunaparvathy I, Hemalatha P, Rajeshwari S, Lavanya Jayabal, Mahilmaran Ayyamperumal, Ramesh P. M., Luke Elizabeth Hanna   +11 more
doaj   +2 more sources

Elastase and Elastase-Inhibitor [PDF]

Nature, 1949
WE have reported in earlier communications1,2 that the extract of fresh pancreas as well as that of acetone-dried pancreas powder contains a specific enzyme which we called 'elastase'. This enzyme had not been found before in the human or animal organism ; but it was studied first by Eijkman3 so early as 1904 as a product of bacteria.
J, BALO, I, BANGA
openaire   +5 more sources

Impact of Mt. Olympus Honeys on Virulence Factors Implicated in Pathogenesis Exerted by Pseudomonas aeruginosa

Antibiotics, 2023
The aim of this study was to examine the impact of twenty honey samples, harvested in Mt. Olympus (Greece), on the virulence factors implicated in P. aeruginosa pathogenesis.
Eleni Tsavea, Paraskevi Tzika, Eleni Katsivelou, Anna Adamopoulou, Marios Nikolaidis, Grigorios D. Amoutzias, Dimitris Mossialos   +6 more
doaj   +1 more source

SARS-CoV-2 Dysregulates Neutrophil Degranulation and Reduces Lymphocyte Counts

Biomedicines, 2022
SARS-CoV-2, the virus that causes COVID-19, has given rise to one of the largest pandemics, affecting millions worldwide. High neutrophil-to-lymphocyte ratios have been identified as an important correlate to poor recovery rates in severe COVID-19 ...
Abenaya Muralidharan, Todd A. Wyatt, St Patrick Reid   +2 more
doaj   +1 more source

Cyanobacteria and microalgae bioactive compounds in skin-ageing: potential to restore extracellular matrix filling and overcome hyperpigmentation

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
As the largest organ in human body, skin acts as a physicochemical barrier, offering protection against harmful environmental stressors, such as chemicals, pathogens, temperature and radiation.
Rita Favas, Janaína Morone, Rosário Martins, Vitor Vasconcelos, Graciliana Lopes   +4 more
doaj   +1 more source

Selenized Chickpea Sprouts Hydrolysates as a Potential Anti-Aging Ingredient

Molecules, 2023
Skin aging represents a health and aesthetic problem that could result in infections and skin diseases. Bioactive peptides can potentially be used in skin aging regulation.
Sayra N. Serrano-Sandoval, Antonio Jiménez-Rodríguez, Jesús Hernández-Pérez, Rocio Alejandra Chavez-Santoscoy, Daniela Guardado-Félix, Marilena Antunes-Ricardo   +5 more
doaj   +1 more source

Pseudomonas aeruginosa Elastase Contributes to the Establishment of Chronic Lung Colonization and Modulates the Immune Response in a Murine Model

Frontiers in Microbiology, 2021
Chronic infection by Pseudomonas aeruginosa in cystic fibrosis (CF) patients is a major contributor to progressive lung damage and is poorly treated by available antibiotic therapy.
Cristina Cigana, Jérôme Castandet, Nicolas Sprynski, Medede Melessike, Lilha Beyria, Serena Ranucci, Serena Ranucci, Beatriz Alcalá-Franco, Alice Rossi, Alessandra Bragonzi, Magdalena Zalacain, Martin Everett   +11 more
doaj   +1 more source

Neutrophil extracellular trap regulators in sickle cell disease: Modulation of gene expression of PADI4, neutrophil elastase, and myeloperoxidase during vaso‐occlusive crisis

Research and Practice in Thrombosis and Haemostasis, 2021
Background Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the pathogenesis of both venous thromboembolism and sickle cell disease (SCD).
Bidossessi Wilfried Hounkpe, Francine Chenou, Igor de Farias Domingos, Evilazio Cunha Cardoso, Marcondes José de Vasconcelos Costa Sobreira, Aderson S. Araujo, Antonio Roberto Lucena‐Araújo, Pedro Vieira da Silva Neto, Adriana Malheiro, Nelson Abrahim Fraiji, Fernando Ferreira Costa, Marcos André C. Bezerra, Magnun Nueldo Nunes Santos, Erich Vinicius De Paula   +13 more
doaj   +1 more source

Potential Anti-aging Components From Moringa oleifera Leaves Explored by Affinity Ultrafiltration With Multiple Drug Targets

Frontiers in Nutrition, 2022
Moringa oleifera (M. oleifera), widely used in tropical and subtropical regions, has been reported to possess good anti-aging benefits on skincare.
Yongbing Xu, Yongbing Xu, Yongbing Xu, Yongbing Xu, Guilin Chen, Guilin Chen, Guilin Chen, Guilin Chen, Mingquan Guo, Mingquan Guo, Mingquan Guo, Mingquan Guo   +11 more
doaj   +1 more source