Results 11 to 20 of about 87,970 (343)

Neutrophil elastase in bronchiectasis

Respiratory Research, 2017
The role of neutrophil elastase (NE) is poorly understood in bronchiectasis because of the lack of preclinical data and so most of the assumptions made about NE inhibitor potential benefit is based on data from CF. In this context, NE seems to be a predictor of long-term clinical outcomes and a possible target of treatment.
A. Gramegna, F. Amati, L. Terranova, Sotgiu, Giovanni, Tarsia, Paolo, Miglietta, Daniela, Calderazzo, Maria Adelaide, S. Aliberti, F. Blasi   +8 more
openaire   +5 more sources

Neutrophil Elastase and Chronic Lung Disease

Biomolecules, 2021
Neutrophil elastase (NE) is a major inflammatory protease released by neutrophils and is present in the airways of patients with cystic fibrosis (CF), chronic obstructive pulmonary disease, non-CF bronchiectasis, and bronchopulmonary dysplasia.
J. Voynow, Meagan Shinbashi
semanticscholar   +1 more source

Flavonoids as inhibitors of human neutrophil elastase

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Elastase is a proteolytic enzyme belonging to the family of hydrolases produced by human neutrophils, monocytes, macrophages, and endothelial cells.
K. Jakimiuk, Jakub Gesek, A. Atanasov, M. Tomczyk   +3 more
semanticscholar   +1 more source

Impact of Mt. Olympus Honeys on Virulence Factors Implicated in Pathogenesis Exerted by Pseudomonas aeruginosa

Antibiotics, 2023
The aim of this study was to examine the impact of twenty honey samples, harvested in Mt. Olympus (Greece), on the virulence factors implicated in P. aeruginosa pathogenesis.
Eleni Tsavea, Paraskevi Tzika, Eleni Katsivelou, Anna Adamopoulou, Marios Nikolaidis, Grigorios D. Amoutzias, Dimitris Mossialos   +6 more
doaj   +1 more source

Selenized Chickpea Sprouts Hydrolysates as a Potential Anti-Aging Ingredient

Molecules, 2023
Skin aging represents a health and aesthetic problem that could result in infections and skin diseases. Bioactive peptides can potentially be used in skin aging regulation.
Sayra N. Serrano-Sandoval, Antonio Jiménez-Rodríguez, Jesús Hernández-Pérez, Rocio Alejandra Chavez-Santoscoy, Daniela Guardado-Félix, Marilena Antunes-Ricardo   +5 more
doaj   +1 more source

Screening of ninety herbal products of commercial interest as potential ingredients for phytocosmetics

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Elastase and tyrosinase are important targets both for cosmetics and for dermatological disorders. In this work, ninety herbal products were tested as inhibitors of these two enzymes. Eleven extracts resulted strongly active.
Mariacaterina Lianza, Manuela Mandrone, Ilaria Chiocchio, Paola Tomasi, Lorenzo Marincich, Ferruccio Poli   +5 more
doaj   +1 more source

Neutrophil extracellular trap regulators in sickle cell disease: Modulation of gene expression of PADI4, neutrophil elastase, and myeloperoxidase during vaso‐occlusive crisis

Research and Practice in Thrombosis and Haemostasis, 2021
Background Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the pathogenesis of both venous thromboembolism and sickle cell disease (SCD).
Bidossessi Wilfried Hounkpe, Francine Chenou, Igor de Farias Domingos, Evilazio Cunha Cardoso, Marcondes José de Vasconcelos Costa Sobreira, Aderson S. Araujo, Antonio Roberto Lucena‐Araújo, Pedro Vieira da Silva Neto, Adriana Malheiro, Nelson Abrahim Fraiji, Fernando Ferreira Costa, Marcos André C. Bezerra, Magnun Nueldo Nunes Santos, Erich Vinicius De Paula   +13 more
doaj   +1 more source

Biochemical Pilot Study on Effects of Pomegranate Seed Oil Extract and Cosmetic Cream on Neurologically Mediated Skin Inflammation in Animals and Humans: A Comparative Observational Study

Molecules, 2023
The presence of phenobarbital and formaldehyde in drugs, food, and beverages can lead to various health issues, including inflammation, oncogenesis, and neurological distress.
Asmaa Fathi Hamouda, Shifa Felemban
doaj   +1 more source

SARS-CoV-2 Dysregulates Neutrophil Degranulation and Reduces Lymphocyte Counts

Biomedicines, 2022
SARS-CoV-2, the virus that causes COVID-19, has given rise to one of the largest pandemics, affecting millions worldwide. High neutrophil-to-lymphocyte ratios have been identified as an important correlate to poor recovery rates in severe COVID-19 ...
Abenaya Muralidharan, Todd A. Wyatt, St Patrick Reid   +2 more
doaj   +1 more source

In vitro screening of elastase, collagenase, hyaluronidase, and tyrosinase inhibitory and antioxidant activities of 22 halophyte plant extracts for novel cosmeceuticals

, 2020
Background Halophyte plant (HPs), a salt-resistant flora, has been reported to provide several health benefits, but the knowledge of its cosmeceutical potential is still ambiguous.
Chanipa Jiratchayamaethasakul, Yuling Ding, Ouibo Hwang, Seung-Tae Im, Yebin Jang, Seungwon Myung, J. Lee, Hyun-Soo Kim, Seok-Chun Ko, Seung-Hong Lee   +9 more
semanticscholar   +1 more source