Results 11 to 20 of about 113,787 (215)

Screening of ninety herbal products of commercial interest as potential ingredients for phytocosmetics

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Elastase and tyrosinase are important targets both for cosmetics and for dermatological disorders. In this work, ninety herbal products were tested as inhibitors of these two enzymes. Eleven extracts resulted strongly active.
Mariacaterina Lianza, Manuela Mandrone, Ilaria Chiocchio, Paola Tomasi, Lorenzo Marincich, Ferruccio Poli   +5 more
doaj   +1 more source

Neutrophil elastase inhibitors [PDF]

Expert Opinion on Therapeutic Patents, 2011
Chronic obstructive pulmonary disease (COPD) constitutes a worldwide health problem. There is currently an urgent and unmet need for the development of small molecule therapeutics capable of blocking and/or reversing the progression of the disorder.
Groutas, William C., Dou, Dengfeng, Alliston, Kevin R.   +2 more
openaire   +3 more sources

Effects of the Syzygium aromaticum L. extract on antioxidation and inhibition of matrix metalloproteinase in human dermal fibroblast

Asian Pacific Journal of Tropical Biomedicine, 2019
Objective: To investigate cosmetic potential of Syzygium aromaticum L. (S. aromaticum L.) and to determine its antioxidant and anti-wrinkling effects. Methods: Using high-performance liquid chromatography, eugenol component was quantitated.
Da Eun Kim, Yeon Sil Hwang, Bo Yoon Chang, Dae Sung Kim, Hyoung Kwon Cho, Sung Yeon Kim   +5 more
doaj   +1 more source

Neutrophil extracellular trap regulators in sickle cell disease: Modulation of gene expression of PADI4, neutrophil elastase, and myeloperoxidase during vaso‐occlusive crisis

Research and Practice in Thrombosis and Haemostasis, 2021
Background Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the pathogenesis of both venous thromboembolism and sickle cell disease (SCD).
Bidossessi Wilfried Hounkpe, Francine Chenou, Igor de Farias Domingos, Evilazio Cunha Cardoso, Marcondes José de Vasconcelos Costa Sobreira, Aderson S. Araujo, Antonio Roberto Lucena‐Araújo, Pedro Vieira da Silva Neto, Adriana Malheiro, Nelson Abrahim Fraiji, Fernando Ferreira Costa, Marcos André C. Bezerra, Magnun Nueldo Nunes Santos, Erich Vinicius De Paula   +13 more
doaj   +1 more source

Aspergillus fumigatus enhances elastase production in pseudomonas aeruginosaco-cultures [PDF]

, 2015
In the cystic fibrosis (CF) lung the presence of bacteria and fungi in the airways promotes an inflammatory response causing progressive lung damage, ultimately leading to high rates of morbidity and mortality.
Kerr, Stephen, Lappin, David F., Mackay, William G., Rajendran, Ranjith, Ramage, Gordon, Smith, Karen, Williams, Craig   +6 more
core   +1 more source

Hemodialysis membrane-related neutrophil dysfunctions and pentoxifylline - a pilot study [PDF]

, 1990
Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo.
Hoffmann, H., Jochum, Marianne, Schiffl, H., Spannagl, Michael   +3 more
core   +1 more source

Echinoclerodane A: A New Bioactive Clerodane-Type Diterpenoid from a Gorgonian Coral <em>Echinomuricea</em> sp.

Molecules, 2012
A new clerodane-type diterpenoid, echinoclerodane A (<strong>1</strong>), was isolated from a Formosan gorgonian coral <em>Echinomuricea</em> sp.
Ching-Hsiao Cheng, Hsu-Ming Chung, Tsong-Long Hwang, Mei-Chin Lu, Zhi-Hong Wen, Yueh-Hsiung Kuo, Wei-Hsien Wang, Ping-Jyun Sung   +7 more
doaj   +1 more source

Specificity of a Polyclonal Fecal Elastase ELISA for CELA3. [PDF]

PLoS ONE, 2016
Elastase is a proteolytic pancreatic enzyme that passes through the gastrointestinal tract undergoing only limited degradation. ELISA tests to determine stool elastase concentrations have therefore been developed for the diagnosis of exocrine pancreatic ...
Frank Ulrich Weiss, Christoph Budde, Markus M Lerch   +2 more
doaj   +1 more source

Budesonide/glycopyrronium/formoterol fumarate triple therapy prevents pulmonary hypertension in a COPD mouse model via NFκB inactivation

Respiratory Research, 2022
Background Chronic obstructive pulmonary disease (COPD) is a health problem that results in death, commonly due to the development of pulmonary hypertension (PH).
Ratoe Suraya, Tatsuya Nagano, Gusty Rizky Teguh Ryanto, Wiwin Is Effendi, Daisuke Hazama, Naoko Katsurada, Masatsugu Yamamoto, Motoko Tachihara, Noriaki Emoto, Yoshihiro Nishimura, Kazuyuki Kobayashi   +10 more
doaj   +1 more source

The Cosmeceutical Potential of the Yellow-Green Alga Trachydiscus minutus Aqueous Extract: Preparation of a Natural-Based Dermal Formula as a Proof of Concept

Cosmetics, 2023
In the present study, selected cosmeceutical properties of aqueous extracts from the microalgae strain Trachydiscus minutus were assessed and compared with those obtained using three widely used Chlorella strains (C. vulgaris, C.
Nikolaos D. Georgakis, Elisavet Ioannou, Marianna Chatzikonstantinou, Marián Merino, Evangelia G. Chronopoulou, José Luis Mullor, Panagiotis Madesis, Nikolaos E. Labrou   +7 more
doaj   +1 more source