Results 31 to 40 of about 115,118 (303)

Diagnostic Performance of Measurement of Fecal Elastase-1 in Detection of Exocrine Pancreatic Insufficiency – Systematic Review and Meta-analysis

Clinical Gastroenterology and Hepatology, 2018
BACKGROUND & AIMS Tests to quantify fecal levels of chymotrypsin like elastase family member 3 (CELA3 or elastase‐1) in feces are widely used to identify patients with exocrine pancreatic insufficiency (EPI). However, the diagnostic accuracy of this test,
R. Vanga, Aylin Tansel, Saad Sidiq, H. El-Serag, Mohamed O. Othman   +4 more
semanticscholar   +1 more source

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines

Cell Reports, 2016
Recent evidence has strongly implicated the IL-1 family cytokines IL-36α, IL-36β, and IL-36γ as key initiators of skin inflammation. Similar to the other members of the IL-1 family, IL-36 cytokines are expressed as inactive precursors and require ...
Conor M. Henry, Graeme P. Sullivan, Danielle M. Clancy, Inna S. Afonina, Dagmar Kulms, Seamus J. Martin   +5 more
doaj   +1 more source

The Cosmeceutical Potential of the Yellow-Green Alga Trachydiscus minutus Aqueous Extract: Preparation of a Natural-Based Dermal Formula as a Proof of Concept

Cosmetics, 2023
In the present study, selected cosmeceutical properties of aqueous extracts from the microalgae strain Trachydiscus minutus were assessed and compared with those obtained using three widely used Chlorella strains (C. vulgaris, C.
Nikolaos D. Georgakis, Elisavet Ioannou, Marianna Chatzikonstantinou, Marián Merino, Evangelia G. Chronopoulou, José Luis Mullor, Panagiotis Madesis, Nikolaos E. Labrou   +7 more
doaj   +1 more source

Glycerol and Natural Deep Eutectic Solvents Extraction for Preparation of Luteolin-Rich Jasione montana Extracts with Cosmeceutical Activity

Metabolites, 2022
Jasione montana is a plant from the family Campanulaceae rich in phenols with health-beneficial properties such as luteolin (LUT) derivatives. In this work, a glycerol-based ultrasound-assisted extraction method was developed and optimized for in total ...
Aleksandra Maria Juszczak, Marijan Marijan, Lejsa Jakupović, Monika Tomczykowa, Michał Tomczyk, Marijana Zovko Končić   +5 more
doaj   +1 more source

Release of Neopterin, PMN Elastase and Terminal Complement Complexes by Orthotopic Liver Transplantation with and without the Use of Veno-venous Bypass

Pteridines, 1998
Aim: The aim of the study was to determine whether orthotopic liver transplantation leads to the activation of macrophages, neutrophils and complement.
Tomasdottir H., Rønholm E., Bengtson JP, Bengtsson A.   +3 more
doaj   +1 more source

Culture Condition Optimization and Pilot Scale Production of the M12 Metalloprotease Myroilysin Produced by the Deep-Sea Bacterium Myroides profundi D25

Molecules, 2015
The protease myroilysin is the most abundant protease secreted by marine sedimental bacterium Myroides profundi D25. As a novel elastase of the M12 family, myroilysin has high elastin-degrading activity and strong collagen-swelling ability, suggesting ...
Xuan Shao, Li-Yuan Ran, Chang Liu, Xiu-Lan Chen, Xi-Ying Zhang, Qi-Long Qin, Bai-Cheng Zhou, Yu-Zhong Zhang   +7 more
doaj   +1 more source

Trappin ovine molecule (TOM), the ovine ortholog of elafin, is an acute phase reactant in the lung [PDF]

, 2004
As large animal models continue to play an important role in translating lung-directed therapeutic strategies from laboratory animals to humans, there is an increasing interest in the analysis of endogenous regulators of inflammation at both a genomic ...
Collie, D David, Tate, Steven, Brown, Thomas I, Mistry, Rohit, Sallenave, Jean-Michel   +4 more
core   +1 more source

Undervalued ubiquitous proteins

4 open, 2019
The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

A point-of-care neutrophil elastase activity assay identifies bronchiectasis severity, airway infection and risk of exacerbation

European Respiratory Journal, 2019
Introduction Neutrophil elastase activity in sputum can identify patients at high risk of airway infection and exacerbations in bronchiectasis. Application of this biomarker in clinical practice is limited, because no point-of-care test is available.
A. Shoemark, E. Cant, L. Carreto, Alexandria H Smith, Martina Oriano, H. Keir, L. Perea, E. Cantó, L. Terranova, S. Vidal, K. Moffitt, S. Aliberti, O. Sibila, J. Chalmers   +13 more
semanticscholar   +1 more source

An Improved Surgical Technique to Increase Neck Width of Elastase-Induced Aneurysm Model in Rabbits: A Prospective Study

Frontiers in Neurology, 2022
BackgroundRabbit elastase-induced aneurysms have widely been used to test various endovascular materials over the past two decades. However, wide-necked aneurysms cannot be stably constructed.ObjectiveThe purpose of the study was to increase the neck ...
Yang Zhang, Yu He, ChaoJie Tang, YuFan Wu, Yi Gu, BinXian Gu, Li Chen, WenWei Gao, ZhiGuo Zhou, YouKe Qi, FaJiang Mao, YongNing Sun, Wu Wang   +12 more
doaj   +1 more source