Results 11 to 20 of about 62,911 (266)

Elastase and Elastase-Inhibitor [PDF]

Nature, 1949
WE have reported in earlier communications1,2 that the extract of fresh pancreas as well as that of acetone-dried pancreas powder contains a specific enzyme which we called 'elastase'. This enzyme had not been found before in the human or animal organism ; but it was studied first by Eijkman3 so early as 1904 as a product of bacteria.
J, BALO, I, BANGA
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Neutrophil extracellular trap regulators in sickle cell disease: Modulation of gene expression of PADI4, neutrophil elastase, and myeloperoxidase during vaso‐occlusive crisis

Research and Practice in Thrombosis and Haemostasis, 2021
Background Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the pathogenesis of both venous thromboembolism and sickle cell disease (SCD).
Bidossessi Wilfried Hounkpe, Francine Chenou, Igor de Farias Domingos, Evilazio Cunha Cardoso, Marcondes José de Vasconcelos Costa Sobreira, Aderson S. Araujo, Antonio Roberto Lucena‐Araújo, Pedro Vieira da Silva Neto, Adriana Malheiro, Nelson Abrahim Fraiji, Fernando Ferreira Costa, Marcos André C. Bezerra, Magnun Nueldo Nunes Santos, Erich Vinicius De Paula   +13 more
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Elastases and Elastin Degradation.

Journal of Investigative Dermatology, 1982
The metabolic turnover of mature elastin fibers in adult animals is relatively slow. Although only small amounts of elastin are degraded normally, increased degradation and fragmentation of elastic fibers may play a significant role in disease processes. Elastinolytic enzymes are found in microorganisms, snake venoms, and in a number of mammalian cells
Werb, Zena, Banda, Michael J., Mckerrow, James H., Sandhaus, Robert A.   +3 more
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Echinoclerodane A: A New Bioactive Clerodane-Type Diterpenoid from a Gorgonian Coral <em>Echinomuricea</em> sp.

Molecules, 2012
A new clerodane-type diterpenoid, echinoclerodane A (<strong>1</strong>), was isolated from a Formosan gorgonian coral <em>Echinomuricea</em> sp.
Ching-Hsiao Cheng, Hsu-Ming Chung, Tsong-Long Hwang, Mei-Chin Lu, Zhi-Hong Wen, Yueh-Hsiung Kuo, Wei-Hsien Wang, Ping-Jyun Sung   +7 more
doaj   +1 more source

Specificity of a Polyclonal Fecal Elastase ELISA for CELA3. [PDF]

PLoS ONE, 2016
Elastase is a proteolytic pancreatic enzyme that passes through the gastrointestinal tract undergoing only limited degradation. ELISA tests to determine stool elastase concentrations have therefore been developed for the diagnosis of exocrine pancreatic ...
Frank Ulrich Weiss, Christoph Budde, Markus M Lerch   +2 more
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Budesonide/glycopyrronium/formoterol fumarate triple therapy prevents pulmonary hypertension in a COPD mouse model via NFκB inactivation

Respiratory Research, 2022
Background Chronic obstructive pulmonary disease (COPD) is a health problem that results in death, commonly due to the development of pulmonary hypertension (PH).
Ratoe Suraya, Tatsuya Nagano, Gusty Rizky Teguh Ryanto, Wiwin Is Effendi, Daisuke Hazama, Naoko Katsurada, Masatsugu Yamamoto, Motoko Tachihara, Noriaki Emoto, Yoshihiro Nishimura, Kazuyuki Kobayashi   +10 more
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Neutrophil elastase inhibitors [PDF]

Expert Opinion on Therapeutic Patents, 2011
Chronic obstructive pulmonary disease (COPD) constitutes a worldwide health problem. There is currently an urgent and unmet need for the development of small molecule therapeutics capable of blocking and/or reversing the progression of the disorder.
Groutas, William C., Dou, Dengfeng, Alliston, Kevin R.   +2 more
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The Cosmeceutical Potential of the Yellow-Green Alga Trachydiscus minutus Aqueous Extract: Preparation of a Natural-Based Dermal Formula as a Proof of Concept

Cosmetics, 2023
In the present study, selected cosmeceutical properties of aqueous extracts from the microalgae strain Trachydiscus minutus were assessed and compared with those obtained using three widely used Chlorella strains (C. vulgaris, C.
Nikolaos D. Georgakis, Elisavet Ioannou, Marianna Chatzikonstantinou, Marián Merino, Evangelia G. Chronopoulou, José Luis Mullor, Panagiotis Madesis, Nikolaos E. Labrou   +7 more
doaj   +1 more source

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines

Cell Reports, 2016
Recent evidence has strongly implicated the IL-1 family cytokines IL-36α, IL-36β, and IL-36γ as key initiators of skin inflammation. Similar to the other members of the IL-1 family, IL-36 cytokines are expressed as inactive precursors and require ...
Conor M. Henry, Graeme P. Sullivan, Danielle M. Clancy, Inna S. Afonina, Dagmar Kulms, Seamus J. Martin   +5 more
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Glycerol and Natural Deep Eutectic Solvents Extraction for Preparation of Luteolin-Rich Jasione montana Extracts with Cosmeceutical Activity

Metabolites, 2022
Jasione montana is a plant from the family Campanulaceae rich in phenols with health-beneficial properties such as luteolin (LUT) derivatives. In this work, a glycerol-based ultrasound-assisted extraction method was developed and optimized for in total ...
Aleksandra Maria Juszczak, Marijan Marijan, Lejsa Jakupović, Monika Tomczykowa, Michał Tomczyk, Marijana Zovko Končić   +5 more
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