Results 51 to 60 of about 87,970 (343)

Gadolinium-Cyclic 1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetraacetic Acid-Click-Sulfonyl Fluoride for Probing Serine Protease Activity in Magnetic Resonance Imaging

Molecules, 2023
Serine protease is linked to a wide range of diseases, prompting the development of robust, selective, and sensitive protease assays and sensing methods.
Phuong Tu Huynh, Huy Duc Vu, Junghwa Ryu, Hee Su Kim, Hoesu Jung, Sung Won Youn   +5 more
doaj   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Pseudomonas aeruginosa isolates from dental unit waterlines can be divided in two distinct groups, including one displaying phenotypes similar to isolates from cystic fibrosis patients

Frontiers in Microbiology, 2015
Pseudomonas aeruginosa displays broad genetic diversity, giving it an astonishing capacity to adapt to a variety of environments and to infect a wide range of hosts. While many P.
Myriam eOuellet, Annie eLeduc, Christine eNadeau, Jean eBarbeau, Steve J Charette   +4 more
doaj   +1 more source

Purification of Human Elastase

Experimental Biology and Medicine, 1972
SummaryElastase was obtained from human pancreas by extraction with sodium acetate buffer, pH 4.5, fractionation with ammonium sulfate, and adsorption on powdered elastin. The enzyme was eluted from elastin with dilute acetic acid and precipitated with ammonium sulfate. An orcein–elastin substrate was used for assay of the enzymatic activity.
Henry D. Moon, James O. Trowbridge
openaire   +3 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Alpha-1 antitrypsin is markedly decreased following pulmonary F. tularensis challenge

Frontiers in Cellular and Infection Microbiology, 2011
Alpha-1 antitrypsin, a small glycoprotein clade A serpine serine protease inhibitor of neutrophil elastase has been shown to increase in humans following bacterial and viral infection.
James Patrick Chambers, James Patrick Chambers, Jieh-Juen eYu, Jieh-Juen eYu, Madhulika eJupelli, Susan T Weintraub, Jose L Lopez-Ribot, Jose L Lopez-Ribot, James J. Valdes, Bernard P. Arulanandam, Bernard P. Arulanandam   +10 more
doaj   +1 more source

Eucalyptus-derived essential oils alleviate microbes and modulate inflammation by suppressing superoxide and elastase release

Frontiers in Pharmacology, 2023
The Eucalyptus tree, belonging to the myrtle family, grows all over the world for its pharmaceutical and industrial benefits. In this article, we present a comparative analysis of the chemical composition of the hydrodistilled oils obtained from three ...
Shaimaa Fayez, Mariam I. Gamal El-Din, Saad A. Moghannem, Faizul Azam, Mohamed El-Shazly, Michal Korinek, Michal Korinek, Yu-Li Chen, Yu-Li Chen, Tsong-Long Hwang, Tsong-Long Hwang, Tsong-Long Hwang, Tsong-Long Hwang, Tsong-Long Hwang, Nouran M. Fahmy   +14 more
doaj   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

Advanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao, Anna Hu, Elnaz Bavel, Chien‐Hsun Yu, Sixuan Zhang, Vera Maria Kissling, Zhihao Li, Thomas Fintan Moriaty, Katharina Maniura‐Weber, Qun Ren   +9 more
wiley   +1 more source

Sterols from the Octocoral Nephthea columnaris

Marine Drugs, 2017
Two new sterols, columnaristerols B (1) and C (2), along with two known analogues, 5,6-epoxylitosterol (3) and litosterol (4), were obtained from the octocoral Nephthea columnaris.
Ta-Yuan Whuang, Hong-Chieh Tsai, Yin-Di Su, Tsong-Long Hwang, Ping-Jyun Sung   +4 more
doaj   +1 more source

Screening and Evaluation of Dermo-Cosmetic Activities of the Invasive Plant Species Polygonum cuspidatum

Plants, 2022
Polygonum cuspidatum (P. cuspidatum) is among the world’s most problematic invasive plant species with negative ecological, socio-economic and security consequences. Management operations in areas invaded systematically generate a large quantity of plant
Vanille Quinty, Cyril Colas, Rouba Nasreddine, Reine Nehmé, Christine Piot, Micheline Draye, Emilie Destandau, David Da Silva, Gregory Chatel   +8 more
doaj   +1 more source