Results 91 to 100 of about 3,029 (158)

Self-assemble peptide biomaterials and their biomedical applications

Bioactive Materials, 2019
Inspired by self-assembling peptides found in native proteins, deliberately designed engineered peptides have shown outstanding biocompatibility, biodegradability, and extracellular matrix-mimicking microenvironments.
Jun Chen, Xuenong Zou
doaj   +1 more source

How conformational transition depends on hydrophobicity of elastin-like polypeptides

The European Physical Journal E, 2010
The three-dimensional structures of elastin-like polypeptides Val1-Pro2-Gly3-Xaa4-Gly5 were investigated by using the multicanonical Monte Carlo (MC) simulation procedure. By substituting different amino acids in the fourth position of the sequence, the thermodynamical variables are calculated in vacuo and in solvent to determine the hydrophobicity ...
Arkin, H., Bilsel, M.
openaire   +3 more sources

Design and evaluation of a bifunctional fusion polypeptide for targeted delivery of tigecycline against drug-resistant Klebsiella pneumoniae

Journal of Nanobiotechnology
The overuse of antibiotics and the continuous evolution of drug-resistant bacteria present substantial obstacles to the clinical treatment of Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections.
Meiling Zhou, Yuming Yao, Shuo Ma, Yaya Chen, GuliNazhaer Abudushalamu, Dawen Chen, Xiao Li, Yan Tao, Yue Hou, Xun Gao, Fengfeng Zhao, Chen Zhang, Hua Shao, Guoqiu Wu   +13 more
doaj   +1 more source

The HELP-UnaG Fusion Protein as a Bilirubin Biosensor: From Theory to Mature Technological Development

Molecules
HUG is the HELP-UnaG recombinant fusion protein featuring the typical functions of both HELP and UnaG. In HUG, the HELP domain is a thermoresponsive human elastin-like polypeptide.
Paola Sist, Ranieri Urbani, Federica Tramer, Antonella Bandiera, Sabina Passamonti   +4 more
doaj   +1 more source

Sequence Control of the Self-Assembly of Elastin-Like Polypeptides into Hydrogels with Bespoke Viscoelastic and Structural Properties. [PDF]

Biomacromolecules, 2023
López Barreiro D, Folch-Fortuny A, Muntz I, Thies JC, Sagt CMJ, Koenderink GH.   +5 more
europepmc   +1 more source

Intracellular Dynamin Elastin-like Polypeptides Assemble into Rodlike, Spherical, and Reticular Dynasomes. [PDF]

Biomacromolecules, 2022
Avila H, Truong A, Tyrpak D, Park SJ, Lei S, Li Y, Okamoto C, Hamm-Alvarez S, MacKay JA.   +8 more
europepmc   +1 more source

A Comprehensive Review on Elastin-Like Polypeptides (ELPs): Characterizations, Synthesis, Purification and Application as Nanoparticles in Drug Delivery of Cancer

Journal of Cancer Biomoleculars and Therapeutics
Cancer is the most challenging disease with high rates of prevalence and mortality in the world. Traditional therapies of cancer include surgery, radiation therapy, and chemotherapy are often unsuccessful in some patients with tumor recurrence. Recently,
Saghar Yousefnia
doaj   +1 more source

Hydra-Elastin-like Polypeptides Increase Rapamycin Potency When Targeting Cell Surface GRP78. [PDF]

Biomacromolecules, 2022
Avila H, Yu J, Boddu G, Phan A, Truong A, Peddi S, Guo H, Lee SJ, Alba M, Canfield E, Yamamoto V, Paton JC, Paton AW, Lee AS, MacKay JA.   +14 more
europepmc   +1 more source

Proline Isomerization Regulates the Phase Behavior of Elastin-Like Polypeptides in Water. [PDF]

J Phys Chem B, 2021
Zhao Y, Kremer K.
europepmc   +1 more source

Intracellular Delivery of a p21-Derived Cell Cycle Inhibitory Peptide Using Elastin-like Polypeptides Suppresses Glioblastoma Cell Proliferation

Molecules
Glioblastoma, with a 5-year survival rate of just under 7.0%, is the most common form of brain cancer in adults. In this study, we evaluated the antiproliferative activity of the biopolymer p21-ELP1-Bac, a p21-derived peptide delivered via an elastin ...
Tiffany Quinn, Yumnaa Shaheen, Drazen Raucher   +2 more
doaj   +1 more source