Results 81 to 90 of about 3,029 (158)

Biomimetic peptide conjugates as emerging strategies for controlled release from protein-based materials

Drug Delivery
Biopolymers, such as collagens, elastin, silk fibroin, spider silk, fibrin, keratin, and resilin have gained significant interest for their potential biomedical applications due to their biocompatibility, biodegradability, and mechanical properties. This
Juthatip Manissorn, Jaturong Promsuk, Kittikhun Wangkanont, Peerapat Thongnuek   +3 more
doaj   +1 more source

Self‐Immolative Gels: Programmable Degradation Using Self‐Immolative Linkers and Polymers

Chemistry – A European Journal, Volume 32, Issue 23, 16 June 2026.
Self‐immolative linkers and polymers undergo bond‐cleaving reaction cascades in response to specific stimuli. Their incorporation into gels can be harnessed to release cargo, induce property changes, or trigger degradation in a highly controlled manner. These functions can be employed in applications such as sensing and drug delivery.
Chuanfeng Li, Elizabeth R. Gillies
wiley   +1 more source

Elastin-like polypeptides: protein-based polymers for biopharmaceutical development

CHIMIA, 2022
Michael A. Nash
doaj   +1 more source

Material engineering and application of hybrid biomimetic-de novo designed elastin-like polypeptides

Communications Materials
The global concern over environmental consequences of petrochemical-derived plastics underscores the urgent need for sustainable and biodegradable polymers.
Zhuoran Geng, Timo Laakko, Ari Hokkanen, Caj Södergård, Ilari Maasilta, Pezhman Mohammadi   +5 more
doaj   +1 more source

Development of elastin-like polypeptide for targeted specific gene delivery in vivo

Journal of Nanobiotechnology, 2020
Background The successful deliveries of siRNA depend on their stabilities under physiological conditions because greater in vivo stability enhances cellular uptake and enables endosomal escape. Viral-based systems appears as most efficient approaches for
Aena Yi, Dahye Sim, Young-Jin Lee, Vijaya Sarangthem, Rang-Woon Park   +4 more
doaj   +1 more source

Broadening Approaches in Nanoparticle Synthesis Through Elastin-Like Polypeptides

Frontiers in Materials, 2022
Eduardo Guisasola
doaj   +1 more source

Heparan sulfates facilitate harmless amyloidogenic fibril formation interacting with elastin-like peptides

Scientific Reports, 2018
Heparan sulfates (HSs) modulate tissue elasticity in physiopathological conditions by interacting with various matrix constituents as tropoelastin and elastin-derived peptides.
Federica Boraldi, Pasquale Moscarelli, Brigida Bochicchio, Antonietta Pepe, Anna M. Salvi, Daniela Quaglino   +5 more
doaj   +1 more source

Multifunctional elastin-like polypeptide renders β-glucosidase enzyme phase transition and high stability

Biotechnology for Biofuels, 2019
Background In the enzymatic conversion of biomass, it becomes an important issue to efficiently and cost-effectively degrade cellulose into fermentable glucose. β-Glucosidase (Bgluc), an essential member of cellulases, plays a critical role in cellulosic
Yang Zhou, Xiaofeng Li, Dandan Yan, Frank Addai Peprah, Xingqi Ji, Emmanuella Esi Fletcher, Yanwei Wang, Yingying Wang, Jie Gu, Feng Lin, Haifeng Shi   +10 more
doaj   +1 more source

Oligomerization triggered by foldon: a simple method to enhance the catalytic efficiency of lichenase and xylanase

BMC Biotechnology, 2017
Background Effective and simple methods that lead to higher enzymatic efficiencies are highly sough. Here we proposed a foldon-triggered trimerization of the target enzymes with significantly improved catalytic performances by fusing a foldon domain at ...
Xinzhe Wang, Huihua Ge, Dandan Zhang, Shuyu Wu, Guangya Zhang   +4 more
doaj   +1 more source

Molecular Engineering of Recombinant Protein Hydrogels: Programmable Design and Biomedical Applications

Gels
Recombinant protein hydrogels have emerged as transformative biomaterials that overcome the bioinertness and unpredictable degradation of traditional synthetic systems by leveraging genetically engineered backbones, such as elastin-like polypeptides, SF,
He Zhang, Jiangning Wang, Jiaona Wei, Xueqi Fu, Junfeng Ma, Jing Chen   +5 more
doaj   +1 more source