Results 21 to 30 of about 645 (131)

Treatment of osteoporosis with eldecalcitol, a new vitamin D analog: a comprehensive review and meta-analysis of randomized clinical trials

Drug Design, Development and Therapy, 2016
Zhixing Xu,1 Changchun Fan,2 Xuechun Zhao,3 Hairong Tao1 1Department of Orthopedic Surgery, The Third People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, People’s Republic of China; 2Department of ...
Xu Z, Fan C, Zhao X, Tao H
doaj   +1 more source

Eldecalcitol improves chair-rising time in postmenopausal osteoporotic women treated with bisphosphonates

Therapeutics and Clinical Risk Management, 2014
Jun Iwamoto,1 Yoshihiro Sato21Institute for Integrated Sports Medicine, Keio University School of Medicine, Tokyo, Japan; 2Department of Neurology, Mitate Hospital, Fukuoka, JapanAbstract: An open-label randomized controlled trial was conducted to ...
Iwamoto J, Sato Y
doaj   +1 more source

Comparison of effectiveness and safety of ibandronate and minodronate combined with eldecalcitol in primary osteoporosis of women: A 1-year follow-up study

Osteoporosis and Sarcopenia, 2017
Objectives: This is an open labeled and retrospective cohort study which compared the effectiveness and safety of ibandronate (IBN) and minodronate (MIN) combined with eldecalcitol (ELD) in primary osteoporosis of women.
Mizue Tanaka, Yukio Nakamura, Soichiro Itoh, Yoshiharu Kato   +3 more
doaj   +2 more sources

Rationale and design of Diabetes Prevention with active Vitamin D (DPVD): a randomised, double-blind, placebo-controlled study

BMJ Open, 2016
Introduction Recent research suggests that vitamin D deficiency may cause both bone diseases and a range of non-skeletal diseases. However, most of these data come from observational studies, and clinical trial data on the effects of vitamin D ...
Yoshiya Tanaka, Yosuke Okada, Tetsuya Kawahara, Gen Suzuki, Tetsuya Inazu, Shoichi Mizuno, Fumiyoshi Kasagi   +6 more
doaj   +2 more sources

Effects of eldecalcitol and ibandronate on secondary osteoporosis and muscle wasting in rats with adjuvant-induced arthritis

Osteoporosis and Sarcopenia, 2018
Objectives: Rheumatoid arthritis (RA) is characterized by chronic inflammation of the synovium, progressive erosion of the articular cartilage, and joint destruction. RA also causes secondary osteoporosis and muscle wasting.
Yuichi Ono, Naohisa Miyakoshi, Yuji Kasukawa, Hiroyuki Nagasawa, Hiroyuki Tsuchie, Manabu Akagawa, Itsuki Nagahata, Yusuke Yuasa, Chiaki Sato, Yoichi Shimada   +9 more
doaj   +2 more sources

Treatment of osteoporosis with eldecalcitol, a new vitamin D analog: a comprehensive review and meta-analysis of randomized clinical trials [Corrigendum]

Drug Design, Development and Therapy, 2016
Zhixing Xu,1 Changchun Fan,2 Xuechun Zhao,3 Hairong Tao11Department of Orthopedic Surgery, The Third People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, People’s Republic of China;  ...
Xu Z, Fan C, Zhao X, Tao H
doaj   +1 more source

Eldecalcitol prevented OVX-induced osteoporosis through inhibiting BMSCs senescence by regulating the SIRT1-Nrf2 signal

Frontiers in Pharmacology, 2023
Background: Aging and oxidative stress are considered to be the proximal culprits of postmenopausal osteoporosis. Eldecalcitol (ED-71), a new active vitamin D derivative, has shown a good therapeutic effect on different types of osteoporosis, but the ...
Yuying Kou, Yuying Kou, Xing Rong, Xing Rong, Rong Tang, Rong Tang, Yuan Zhang, Yuan Zhang, Panpan Yang, Panpan Yang, Hongrui Liu, Hongrui Liu, Wanli Ma, Wanli Ma, Minqi Li, Minqi Li   +15 more
doaj   +1 more source

Eldecalcitol effectively prevents alveolar bone loss by partially improving Th17/Treg cell balance in diabetes-associated periodontitis

Frontiers in Bioengineering and Biotechnology, 2023
Background: Diabetes-associated periodontitis (DPD) is an inflammatory and destructive disease of periodontal tissues in the diabetic population. The disease is manifested as more severe periodontal destruction and is more difficult to treat when ...
Ruihan Gao, Ruihan Gao, Weidong Zhang, Weidong Zhang, Yujun Jiang, Yujun Jiang, Junzhe Zhai, Jian Yu, Hongrui Liu, Hongrui Liu, Minqi Li, Minqi Li   +11 more
doaj   +1 more source

Efficacy and Safety of Eldecalcitol for Osteoporosis: A Meta-Analysis of Randomized Controlled Trials

Frontiers in Endocrinology, 2022
ObjectEldecalcitol (ED-71) is a vitamin D analog for the treatment of osteoporosis. However, inconsistent results have been reported in this regard. Hence, this meta-analysis of randomized controlled trials (RCTs) aimed to assess the efficacy and safety ...
Hongyan Liu, Guoqi Wang, Ting Wu, Yiming Mu, Weijun Gu   +4 more
doaj   +1 more source

A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures : A randomized, active comparator, double-blind study [PDF]

, 2011
Background: Eldecalcitol is an analog of 1,25-dihydroxyvitamin D3 that improves bone mineral density; however, the effect of eldecalcitol on the risk of fractures is unclear.
Shiraki, Masataka, マツモト, トシオ, Fukunaga, Masao, 松本, 俊夫, Ito, Masako, 1591, Tanigawara, Yusuke, Hirota, Takako, Hayashi, Yasufumi, Nakamura, Toshitaka, Matsumoto, Toshio, 20157374, 60162/profile-ja.html, Sone, Teruki   +13 more
core   +2 more sources