Results 31 to 40 of about 756 (179)

Long-Term Sequential Therapy for Pregnancy- and Lactation-Associated Osteoporosis With Multiple Vertebral Fractures: A Case Report of Over 5 Years. [PDF]

Case Rep Obstet Gynecol
Background Pregnancy‐ and lactation‐associated osteoporosis (PLO) is a rare condition that may cause multiple vertebral fractures during late pregnancy or the postpartum period. Evidence regarding treatment strategies remains limited, particularly regarding long‐term outcomes of sequential regimens combining anabolic and antiresorptive therapies.
Tsuchimochi K, Tsuchimochi H.
europepmc   +2 more sources

Clinical Pharmacist's Role in Preventing and Managing Drug-Induced Oral Ulceration: A Bisphosphonate Case in an Older Adult Care Setting. [PDF]

Case Rep Dent
Bisphosphonate‐induced oral mucosal ulcers are rare adverse events distinct from medication‐related osteonecrosis of the jaw. This case demonstrates successful conservative management through the modification of drug administration in an older adult care facility.
Sano M, Iijima Y, Yamada M, Hino S, Shinogi M, Horie N, Kaneko T.   +6 more
europepmc   +2 more sources

Eldecalcitol

Reactions Weekly, 2017
openaire   +2 more sources

Comparison of Efficacy and Safety of Denosumab with Eldecalcitol or Native Vitamin D in Postmenopausal Chinese Women with Osteoporosis (ESCORT): A Randomized Controlled Trial. [PDF]

J Clin Med
Background: Eldecalcitol (ELD) and denosumab are some of the most common therapeutic options for osteoporosis management. ELD effectively increases bone mineral density (BMD) in osteoporotic patients, independent of baseline vitamin D status or calcium ...
Zeng Y, Tang Q, Yang J, Li Q, Yang L, Zhang B, Yang M, Che M, Peng Y.   +8 more
europepmc   +2 more sources

Eldecalcitol effectively prevents alveolar bone loss by partially improving Th17/Treg cell balance in diabetes-associated periodontitis

Frontiers in Bioengineering and Biotechnology, 2023
Background: Diabetes-associated periodontitis (DPD) is an inflammatory and destructive disease of periodontal tissues in the diabetic population. The disease is manifested as more severe periodontal destruction and is more difficult to treat when ...
Ruihan Gao, Ruihan Gao, Weidong Zhang, Weidong Zhang, Yujun Jiang, Yujun Jiang, Junzhe Zhai, Jian Yu, Hongrui Liu, Hongrui Liu, Minqi Li, Minqi Li   +11 more
doaj   +1 more source

Treatment of osteoporosis with eldecalcitol, a new vitamin D analog: a comprehensive review and meta-analysis of randomized clinical trials [Corrigendum]

Drug Design, Development and Therapy, 2016
Zhixing Xu,1 Changchun Fan,2 Xuechun Zhao,3 Hairong Tao11Department of Orthopedic Surgery, The Third People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, People’s Republic of China;  ...
Xu Z, Fan C, Zhao X, Tao H
doaj   +1 more source

Exploring the factors associated with difficulties in extracting tablets or capsules from press-through-package sheets. [PDF]

Br J Clin Pharmacol
Abstract Exploring factors related to difficulties in extracting tablets or capsules from press‐through‐packages is essential for optimizing the dosage form. To achieve this, the involvement of patient insight is important. In the present study, the preferences of patients regarding drugs that are difficult to extract from their packaging were ...
Tsuchiya M, Imai S, Asano M, Shimizu Y, Kizaki H, Ito Y, Tsuchiya M, Kuriyama R, Yoshida N, Shimada M, Sando T, Ishijima T, Hori S.   +12 more
europepmc   +2 more sources

A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures : A randomized, active comparator, double-blind study [PDF]

, 2011
Background: Eldecalcitol is an analog of 1,25-dihydroxyvitamin D3 that improves bone mineral density; however, the effect of eldecalcitol on the risk of fractures is unclear.
Shiraki, Masataka, マツモト, トシオ, Fukunaga, Masao, 松本, 俊夫, Ito, Masako, 1591, Tanigawara, Yusuke, Hirota, Takako, Hayashi, Yasufumi, Nakamura, Toshitaka, Matsumoto, Toshio, 20157374, 60162/profile-ja.html, Sone, Teruki   +13 more
core   +3 more sources

Overview of the clinical efficacy and safety of eldecalcitol for the treatment of osteoporosis

Archives of Osteoporosis, 2022
AbstractSummaryEldecalcitol (ELD) is a new oral analog of the active form of vitamin D with anti-resorptive properties. We conducted a meta-analysis to investigate the efficacy and safety of ELD in osteoporosis. Compared with alfacalcidol, ELD significantly lowered vertebral facture risk, increased bone mineral density, but also had a higher risk of ...
Cui, Lijia, Xia, Weibo, Yu, Chuan, Dong, Shuangshuang, Pei, Yu   +4 more
openaire   +2 more sources

Eldecalcitol, a second-generation vitamin D analog, drives bone minimodeling and reduces osteoclastic number in trabecular bone of ovariectomized rats [PDF]

, 2011
To elucidate the histological events that follow administration of eldecalcitol, a second-generation of vitamin D analog currently awaiting approval as a drug for treatment of osteoporosis, we employed the ovariectomy (OVX) rat model.
Kimimitsu Oda, Saito, H., Hasegawa, Tomoka, de Freitas, Paulo Henrique Luiz, Paulo Henrique Luiz de Freitas, Li, Minqi, Muneteru Sasaki, Norio Amizuka, Oda, Kimimitsu, Takeda, S., Sasaki, M., Li, M., Hitoshi Saito, Sasaki, Muneteru, Oda, K., Freitas, PHL., Takeda, Satoshi, Amizuka, Norio, Tabata, C., Hasegawa, T., Amizuka, N., Minqi Li, Tabata, Chihiro, Tomoka Hasegawa, Satoshi Takeda, Chihiro Tabata, Saito, Hitoshi   +26 more
core   +1 more source