Results 41 to 50 of about 795 (185)

Combination treatment with ibandronate and eldecalcitol prevents osteoporotic bone loss and deterioration of bone quality characterized by nano-arrangement of the collagen/apatite in an ovariectomized aged rat model [PDF]

, 2022
Ozasa R., Saito M., Ishimoto T., et al. Combination treatment with ibandronate and eldecalcitol prevents osteoporotic bone loss and deterioration of bone quality characterized by nano-arrangement of the collagen/apatite in an ovariectomized aged rat ...
Saito, Mitsuru, Ishimoto, Takuya, Nakano, Takayoshi, Ozasa, Ryosuke, Matsumoto, Yoshihiro, Matsugaki, Aira, Ryosuke Ozasa, Takuya Ishimoto, Takayoshi Nakano, Aira Matsugaki, Mitsuru Saito, Yoshihiro Matsumoto   +11 more
core   +1 more source

Effects of risedronate, alendronate, and minodronate alone or in combination with eldecalcitol on bone mineral density, quality, and strength in ovariectomized rats

Bone Reports, 2021
Combination therapy of active vitamin D3 with some bisphosphonates (BPs) has been reported to be clinically beneficial. However, combination therapy of eldecalcitol (ELD) with BP has to date not been validated as to whether it is beneficial in the ...
Tetsuo Yano, Teppei Ito, Yuya Kanehira, Mei Yamada, Hiromi Kimura-Suda, Hirotaka Wagatsuma, Daisuke Inoue   +6 more
doaj   +1 more source

SPIRIT checklist

, 2022
The document indicates the SPIRIT checklist for the  protocol: a randomized study of the efficacy of ibandronic acid plus eldecalcitol in patients with gastric cancer after gastrectomy: A comparative study of different routes of administration of ...
Hisaki Aiba (12989435)
core   +1 more source

case report form.xlsx

, 2022
The data includes the sample of case report in the protocol article: a randomized study of the efficacy of ibandronic acid plus eldecalcitol in patients with gastric cancer after gastrectomy: A comparative study of different routes of administration of ...
Hisaki Aiba (12989435)
core   +1 more source

Eldecalcitol Induces Minimodeling-Based Bone Formation and Inhibits Sclerostin Synthesis Preferentially in the Epiphyses Rather than the Metaphyses of the Long Bones in Rats. [PDF]

Int J Mol Sci
This study aimed to examine minimodeling-based bone formation between the epiphyses and metaphyses of the long bones of eldecalcitol (ELD)-administered ovariectomized rats.
Hasegawa T, Yamamoto T, Hongo H, Yamamoto T, Haraguchi-Kitakamae M, Ishizu H, Shimizu T, Saito H, Sakai S, Yogo K, Matsumoto Y, Amizuka N.   +11 more
europepmc   +2 more sources

Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol [PDF]

BoneKEy Reports, 2014
Eldecalcitol [1α,25-dihydroxy-2β-(3-hydroxypropyloxy)vitamin D3] is an analog of 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3], bearing a hydroxypropyloxy residue at the 2β position. In preclinical studies, eldecalcitol suppressed bone resorption to a greater extent than alfacalcidol but had a similar effect on bone formation and Ca metabolism, resulting in ...
Toshio, Matsumoto, Toshiyuki, Takano, Hitoshi, Saito, Fumiaki, Takahashi   +3 more
openaire   +2 more sources

ED-71 Prevents Glucocorticoid-Induced Osteoporosis by Regulating Osteoblast Differentiation via Notch and Wnt/β-Catenin Pathways

Drug Design, Development and Therapy, 2022
Xing Rong,1,2 Yuying Kou,1,2 Yuan Zhang,1,2 Panpan Yang,1,2 Rong Tang,1,2 Hongrui Liu,1,2 Minqi Li1,2 1Department of Bone Metabolism, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral ...
Rong X, Kou Y, Zhang Y, Yang P, Tang R, Liu H, Li M   +6 more
doaj  

Relationship between vitamin D deficiency and early implant failure and osseointegration

Periodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron, Nathan E. Estrin, Ana Paz, Reinhard Gruber, Nima Farshidfar, Yufeng Zhang, Anton Sculean, Thomas G. Wiedemann, Paras Ahmad   +8 more
wiley   +1 more source

Effects of eldecalcitol on cortical bone response to mechanical loading in rats [PDF]

BMC Musculoskeletal Disorders, 2015
Mechanical loading of bones activates modeling and suppresses remodeling by promoting bone formation. Eldecalcitol is approved for the treatment of osteoporosis in Japan and is often used in patients undergoing exercise therapy. However, the effects of eldecalcitol on bone formation during mechanical loading are unknown.
Yamasaki, Yusuke, Nagira, Keita, Osaki, Mari, Nagashima, Hideki, Hagino, Hiroshi   +4 more
openaire   +2 more sources

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source