Results 21 to 30 of about 43,957 (340)
Environmental risk factors and their footprints in vivo – a proposal for the classification of oxidative stress biomarkers [PDF]
, 2020 Environmental agents, including socioeconomic condition, and host factors can act as causal agents and risk factors in disease. We use biomarkers and sociomarkers to study causal factors, such as overproduction of reactive oxygen species (ROS) which ...
Ghezzi, Pietro
core +1 more source
Scientific Reports, 2022 The ion channel TRPA1 is a promiscuous chemosensor, with reported response to a wide spectrum of noxious electrophilic irritants, as well as cold, heat, and mechanosensation.
Matthew Habgood +4 more
doaj +1 more source
The MarR-Type Repressor MhqR Confers Quinone and Antimicrobial Resistance in Staphylococcus aureus [PDF]
, 2019 Aims: Quinone compounds are electron carriers and have antimicrobial and toxic properties due to their mode of actions as electrophiles and oxidants.
Fritsch, Verena Nadin +9 more
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Electrophilic Fluorination of Organosilanes
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tredwell, M, Gouverneur, V
openaire +3 more sources
Redox Biology, 2023 Cysteine residues can undergo multiple posttranslational modifications with diverse functional consequences, potentially behaving as tunable sensors.
Patricia González-Jiménez +6 more
doaj +1 more source
Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones [PDF]
, 2013 2-Substituted oxetan-3-ones can be prepared in good yields and enantioselectivities (up to 84% ee) by the metalation of the SAMP/RAMP hydrazones of oxetan-3-one, followed by reaction with a range of electrophiles that include alkyl, allyl, and benzyl ...
Beasley, Benjamin +3 more
core +1 more source
KEAP1/NRF2 as a druggable target [PDF]
Arhiv za farmaciju, 2023 Nuclear factor erythroid 2-related factor 2 (NRF2; encoded by NFE2L2) is an inducible transcription factor that regulates the expression of a large network of genes encoding proteins with cytoprotective functions.
Dinkova-Kostova Albena T.
doaj
Functional evidence of distinct electrophile-induced activation states of the ion channel TRPA1
Biochemistry and Biophysics Reports, 2021 Transient Receptor Potential Ankyrin 1 (TRPA1) is a tetrameric, nonselective cation channel expressed on nociceptive sensory nerves whose activation elicits nocifensive responses (e.g. pain).
Thomas A. Parks +2 more
doaj +1 more source
Asymmetric additions to dienes catalysed by a dithiophosphoric acid. [PDF]
, 2011 Chiral Brønsted acids (proton donors) have been shown to facilitate a broad range of asymmetric chemical transformations under catalytic conditions without requiring additional toxic or expensive metals.
Hamilton, Gregory +4 more
core +5 more sources
Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?
Antioxidants, 2017 Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates hundreds of antioxidant genes, and is activated in response to oxidative stress.
Jeffrey R. Liddell
doaj +1 more source