Results 81 to 90 of about 22,971 (281)
Systematic study of the employment of enzymatic catalysts on the formation of carbon-heteroatoms
Orbital: The Electronic Journal of Chemistry, 2012 The classic thio-Michael reaction is the one that involves the addition of a sulfur atom like the nucleophile of the reaction to an electrophile α,β -insaturated.
Paula Vanessa S. Rizzo +6 more
doaj +1 more source
Sulfone Electrophiles in Cross-Electrophile Coupling: Nickel-Catalyzed Difluoromethylation of Aryl Bromides [PDF]
Fluoroalkyl fragments have played a critical role in the design of pharmaceutical and agrochemical molecules in recent years due to the enhanced biological properties of fluorinated molecules compared to their non-fluorinated analogues.
Sebastien, Monfette +5 more
core +1 more source
Electrophilic Selenium Catalysis with Electrophilic N-F Reagents as the Oxidants [PDF]
Molecules, 2017 A suitable oxidative system is crucial to electrophilic selenium catalysis (ESC). This short review offers the overview of recent development in ESC with electrophilic N-F reagents as the oxidants. Several highly selective transformations of alkenes such as allylic or vinylic imidation, pyridination, syn-dichlorination, oxidative cyclization and ...
Ruizhi Guo, Lihao Liao, Xiaodan Zhao
openaire +3 more sources
Beilstein Journal of Organic Chemistry, 2016 Hydrogen bond donor catalysis represents a rapidly growing subfield of organocatalysis. While traditional hydrogen bond donors containing N–H and O–H moieties have been effectively used for electrophile activation, activation based on other types of non ...
Pavel Nagorny, Zhankui Sun
doaj +1 more source
Nickel-Catalyzed Regioselective Cross-Electrophile Alkene Difunctionalization
, 2023 Nickel-catalyzed alkene difunctionalization processes with two different carbon electrophiles can lead to the facile formation of many different types of C–C bonds.
Quirion, Kevin
core
Ni-Catalyzed Remote Radical/Cross-Electrophile Coupling Cascade for Selective C(sp3)H Arylation
, 2022 An innovative 1,5-HAT cascade strategy has been advanced for the nickel-catalyzed distal arylation via cross-electrophile coupling. Through specific migration, the remote C(sp3)–H bond is regioselectively activated, and Ar–I as the available ...
Bin Wang +15 more
core +1 more source
Angewandte Chemie, EarlyView.In this work, we present a new class of unusual charged Fe(I)‐bisphosphine‐ates, along with full characterization of their structure and bonding, utilizing low‐temperature synthetic and spectroscopic and techniques. These complexes are highly reactive toward catalytically relevant electrophiles, and can serve as valuable synthons providing access to ...
Egor Kokin +3 more
wiley +2 more sources
Chemoselective reactions of electrophiles with quinazoline amides; 3-alkylquinazoline-2,4-(1H,3H)-diones, and 2-arylquinazoline-4(3H)ones and their thioamide regioisomers [PDF]
Alfarama Journal of Basic & Applied SciencesThe study draws a solid theoretical basis governing the reaction of amides and thioamides with electrophiles to give either N, O or S- substitutions.
mohamed Abd El-Moneim +3 more
doaj +1 more source
Difluoromethylenation of Alkynes: Streamlined Access to Allyl Difluorides
Angewandte Chemie, EarlyView.Stabilizing primary oxocarbenium in HF/pyridine unlocks a direct alkyne difluoromethylenation – an efficient route to synthetically‐relevant allyl difluorides in a single step. ABSTRACT A direct difluoromethylenation of alkynes has been developed using HF/pyridine as a dual acidic and fluorinating medium. The reaction proceeds via in situ generation of
Fabien Naullet +4 more
wiley +2 more sources
γ-Hydroxynitrile Alkylations: Electrophile-Dependent Stereoselectivity
, 2016 Quaternary centers are efficiently installed in chelation-controlled alkylations of acyclic hydroxynitriles. Intriguingly, the stereoselectivity is determined by the nature of the electrophile and the structure of the Grignard used for the deprotonation.
Fraser F. Fleming (1520524) +2 more
core +2 more sources