Results 121 to 130 of about 222,058 (260)

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Deep Eutectic Solvents in Capillary Electromigration Techniques-A Review of Recent Advancements. [PDF]

Molecules
Pieckowski M, Olędzka I, Bączek T, Kowalski P.   +3 more
europepmc   +1 more source

PEGylation of polymerized albumin retains colloid osmotic pressure: Towards an enhanced potential plasma substitute

Biotechnology Progress, EarlyView.
Abstract Plasma expanders (PEs) are commonly used to replace lost blood volume for septic shock patients with increased vascular permeability. Human serum albumin (HSA) is the preferred PE, due to its innate ability to restore blood colloid osmotic pressure (COP).
Amna Abdalbaqi, Ahmad Yahya, Krianthan Govender, Carlos Muñoz, Gala Sanchez Van Moer, Daniela Lucas, Pedro Cabrales, Andre F. Palmer   +7 more
wiley   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

Capillary Electrophoresis Can Detect the Simultaneous Presence of Hairpins and Self-Dimers in Non-Symmetric, Single-Stranded DNA Oligomers. [PDF]

Electrophoresis
Stellwagen E, Stellwagen NC.
europepmc   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

Genotyping of Coxiella burnetii isolates in Iran using Multiple-locus variable-number tandem repeat analysis (MLVA). [PDF]

BMC Microbiol
Dolatkhah F, Moradkasani S, Mohabati Mobarez A, Khalili M, Mostafavi E, Tadayon K, Esmaeili S.   +6 more
europepmc   +1 more source

Antitumor and Cytogenotoxic Activities of Libidibia ferrea Hydroalcoholic Extracts in Murine Breast Carcinoma

Chemistry &Biodiversity, EarlyView.
ABSTRACT Breast cancer is the most prevalent cancer type among women worldwide, and there is a critical need for more effective and safer treatments, especially for aggressive and therapy‐resistant subtypes. Libidibia ferrea, a native plant from Brazil, exhibits anti‐inflammatory, antimicrobial, antioxidant, and antitumor properties.
Diego Pereira de Menezes, Evaldo dos Santos Monção Filho, Atanara Alves de Sousa, João Pedro Alves Damasceno do Lago, Karla Darlianny Mourão Cavalcante, Fernanda Alves de Sousa Cavalcante, Irismara Sousa Silva, Marina Pinto Sanches, Semiramis Jamil Hadad do Monte, Ester Miranda Pereira, Paulo Michel Pinheiro Ferreira, Joao Marcelo de Castro e Sousa, Gerardo Magela Vieira Júnior, Dalton Dittz   +13 more
wiley   +1 more source

Coupling Capillary Electrophoresis With a Shifted Inlet Potential High-Resolution Ion Mobility Spectrometer. [PDF]

Electrophoresis
Welters K, Thoben C, Raddatz CR, Schlottmann F, Zimmermann S, Belder D.   +5 more
europepmc   +1 more source

Amazonian Cyanobacteria as a Source of Bioactive Compounds With Antimicrobial and Cytotoxic Properties

Chemistry &Biodiversity, EarlyView.
ABSTRACT Cyanobacteria are photosynthetic microorganisms known for producing diverse bioactive compounds. This study explores the bioactivity of extracts and fractions from Amazonian cyanobacteria and their pigment and phenolic compound production. A fraction from Synechococcus sp. CACIAM 05 showed cytotoxicity against hCMEC/D3 and MG‐63 cells.
Samuel Cavalcante do Amaral, Luciana Pereira Xavier, Mariana Reis, Rhuana V. Médice, Janaína Morone, Raquel Silva, João Morais, Vitor Vasconcelos, Agenor Valadares Santos   +8 more
wiley   +1 more source