Results 171 to 180 of about 227,547 (293)

Improvement of EPO Transgene Detection From Polymeric Dried Blood Spots for Antidoping Application

Drug Testing and Analysis, EarlyView.
This article presents an optimized protocol for gene doping detection. Starting from one spot DBS (20 μL), concentrated DNA was obtained and real‐time PCR parameters were adjusted for increased detection. Robust detection of 5000 copies/mL of transgene was validated for polymeric device TASSO M‐20.
Alexandre Marchand, Ingrid Roulland, Magnus Ericsson   +2 more
wiley   +1 more source

Quantifying Biomolecular Interactions in High-Conductivity Samples With Capillary Electrophoresis. [PDF]

J Sep Sci
De Silva M, Aruna S, Samarakoon B, Whelan RJ.   +3 more
europepmc   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Caught by Whole-Exome Sequencing: Hemoglobin Sun Prairie in a Patient With Unexplained Hemolytic Anemia From Nepal. [PDF]

Case Rep Hematol
Upadhaya P, Shrestha A.
europepmc   +1 more source

Reviews of High‐Longevity Aqueous Zinc Metal Batteries Achieved by Programmable Interface Architectures

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review focuses on the mechanisms of Zn2+ electrodeposition and interfacial failure together with systematical artificial interphase layer design strategies from carbon materials, zincophilic alloys, to inorganic/organic compound layers, regulating ion flux and desolvation and providing guidance for programmable interface construction in aqueous ...
Bixian Chen, Xiaomin Cheng, Haifeng Yang, Teng Li, Jing Dong, Yidong Miao, Yongzheng Zhang, Qingbo Xiao, Qinghua Guan, Jing Zhang, Yunjian Liu, Hongzhen Lin, Jian Wang   +12 more
wiley   +1 more source

Capillary-Based Physicochemical Characterization of Lipid Nanoparticles. [PDF]

Electrophoresis
Kuzucu EÜ, Schittny V, Huwyler J, Schwarz MA.   +3 more
europepmc   +1 more source

Characterizing the Lanthanide‐Binding Tag Grafted at Calmodulin Site 1: Affinity, Selectivity, and Coordination Properties

European Journal of Inorganic Chemistry, EarlyView.
Lanthanide affinity and selectivity in proteins remain poorly understood. Engineering calmodulin with a lanthanide‐binding tag at Site 1 boosts affinity from nanomolar (isolated LBTs) to picomolar dissociation constants, comparable to lanmodulin but with distinct selectivity.
Catherine Berthomieu, Manon Martin, Jean Aupiais, Tiffanie Barré, Loïc Daronnat, Jérémy Pansier, Nicolas Brémond, David Lemaire, Atul Thawari, Martin Levier, Laurence Berthon, Sandrine Sauge‐Merle   +11 more
wiley   +1 more source

Genetic diversity, population structure, and drug resistance of Plasmodium falciparum in Kenya: a systematic review and meta-analysis. [PDF]

Malar J
Nyataya JN, Mutsaers M, Masakhwe CA, Laigong AC, Kattenberg JH, Rosanas-Urgell A, Waitumbi JN.   +6 more
europepmc   +1 more source

Long‐Read, High‐Resolution Sanger Sequencing by Micelle‐Tagging Electrophoresis

ELECTROPHORESIS, EarlyView.
ABSTRACT We demonstrate a gel‐free electrophoretic separation of Sanger sequencing fragments up to 782 bases in length using nonionic wormlike micelles as drag‐tags in micelle‐tagging electrophoresis (MTE). This is an increase of 280 bases over previous MTE methods and a nearly three‐fold improvement over end‐labeled free‐solution electrophoresis ...
Randall Gamble, H. Michael Wenz, Bashar Mullah, James W. Schneider   +3 more
wiley   +1 more source

Sensitive Profiling of Human Milk Oligosaccharides in Human Colostrum and Breast Milk by Capillary Electrophoresis-Mass Spectrometry. [PDF]

J Sep Sci
Smolkova D, Rusin M, Dobrowolska-Iwanek J, Woźniakiewicz M, Lavicka J.   +4 more
europepmc   +1 more source