Results 91 to 100 of about 112,448 (255)
Illuminating the Intracellular World: Breakthroughs in Nanoscale Optoelectronics
Advanced Electronic Materials, EarlyView.This perspective explores optoelectronic biointerfaces spanning macroscale flexible devices to nanoscale intracellular systems, emphasizing their integration across dimensions. It examines capacitive, Faradaic, and photothermal mechanisms that enable light‐driven control of cellular activity and highlights key material and design challenges in ...
Tania Assaf, Menahem Y. Rotenberg
wiley +1 more source
Cavity Microelectrode Arrays for Electrical Recordings From Neurons
Advanced Electronic Materials, EarlyView.Microelectrode arrays (MEAs) are used to study electrophysiological activity. However, their signals are small with high noise. By adding a 100‐nanometer‐high cavity above the electrode, which reduces impedance without affecting resolution, we improve signal quality.
Johannes Lewen +2 more
wiley +1 more source
Cardiac Ablation by Electroporation
JACC: Clinical Electrophysiology, 2018 In a recent State-of-the-Art Review article, Wittkampf et al. [(1)][1] offered their view on irreversible electroporation (IRE) as a promising and potentially disruptive technology in cardiac ablation for pulmonary vein isolation.
openaire +2 more sources
Development of immunocompetent models for primary and metastatic ER+ breast cancer
Animal Models and Experimental Medicine, EarlyView.This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull +5 more
wiley +1 more source
626 Improving the yeast transformation efficiency for yeast display in antibody development
Journal for ImmunoTherapy of Cancer, 2020 Jian Chen, George Sun
doaj +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Irreversible Electroporation in Medicine
Technology in Cancer Research & Treatment, 2007 This is a brief introduction to the emerging field of irreversible electroporation in medicine. Certain electrical fields when applied across a cell can have as a sole effect the permeabilization of the cell membrane, presumable through the formation of nanoscale defects in the cell membrane.
openaire +2 more sources
535 Electroporation of B cells is correlated with cell size change during B cell expansion
Journal for ImmunoTherapy of Cancer, 2020 Jian Chen, George Sun
doaj +1 more source
MicromachinesIn situ electroporation, a non-invasive technique for enhancing the permeability of cell membranes, has emerged as a powerful tool for intracellular delivery and manipulation. This method allows for the precise introduction of therapeutic agents, such as
Haizhen Sun +4 more
doaj +1 more source
Advanced NanoBiomed Research, EarlyView.CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham +8 more
wiley +1 more source