Endoscopic small bowel therapies for type 2 diabetes
Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel +4 more
wiley +1 more source
Non-viral in vivo electroporation-based chromosomal engineering and repair assessment in the murine uterine epithelium. [PDF]
Iwata S, Miura Y, Iwamoto T.
europepmc +1 more source
Irreversible Electroporation for Tonsillar Ablation in Adults
Abstract Objective To evaluate the safety and efficacy of irreversible electroporation for non‐thermal ablation of tonsils in adults. Study Design Prospective interventional case series of 24 adult patients referred for tonsillectomy that were followed for 3 months. Setting Academic medical center.
Codrut Sarafoleanu +4 more
wiley +1 more source
Low-Dose Vitamin C-Based Electroporation of Solid Tumors: A New Area in Non-Cytotoxic Electrochemotherapy. [PDF]
YazdanParast SM +2 more
europepmc +1 more source
Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá +4 more
wiley +1 more source
Contrast-enhanced ultrasound as a problem-solving tool and irreversible electroporation for a perivascular/peribiliary segment IVs colorectal liver metastasis: a case report. [PDF]
Romeo M +8 more
europepmc +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
Electroporation as an adjunctive therapy for refractory feline sporotrichosis: A two-case report. [PDF]
Brunner CHM, Gonçalves LEP, Hirukawa C.
europepmc +1 more source
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji +13 more
wiley +1 more source

