Andrology, EarlyView.ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino +5 more
wiley +1 more source
Fast and efficient intracellular delivery of large size nanoparticles into mammalian cells by in situ electroporation. [PDF]
Sci RepMaschietto M +3 more
europepmc +1 more source
Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice
Andrology, EarlyView.ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda +2 more
wiley +1 more source
Developing High-Efficiency Electroporation Protocols for Hard-To-Transform Halomonas spp. [PDF]
Microb BiotechnolCoimbra AAB, White IJ, Rios-Solis L.
europepmc +1 more source
Focal therapy using a novel cooled laser device for prostate cancer: early trial results
BJU International, EarlyView.Objectives To determine the short‐term oncological results and safety of the ProFocal Laser Therapy for Prostate Tissue Ablation (PFLT‐PC) trial, the first phase II clinical trial of ProFocal® (Medlogical Innovations, Sydney, Australia), a novel, cooled laser focal therapy (cLFT) device for prostate cancer (PCa) treatment. Patients and Methods Men with
Jonathan Kam +17 more
wiley +1 more source
Carrot extracellular nanovesicles as carotenoid carriers in an in vitro macular degeneration model. [PDF]
Sci RepTapia-Aguayo A +5 more
europepmc +1 more source
BJU International, EarlyView.Objective To assess the oncological outcomes of targeted microwave ablation (TMA) using organ‐based tracking (OBT) Fusion® via KOELIS Trinity® (KOELIS, Meylan, France) in men with intermediate‐risk prostate cancer (PCa): the VIOLETTE trial (ClinicalTrials.gov identifier: NCT04582656) Patients and Method In this prospective phase II, multicentre ...
Nicolas Barry Delongchamps +11 more
wiley +1 more source
Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?
British Journal of Pharmacology, EarlyView.Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi +10 more
wiley +1 more source
Transient mRNA-based CD117 CAR T cells effectively target acute myeloid leukemia <i>in vitro</i> for potential use as a preconditioning strategy. [PDF]
Immunooncol TechnolInthanachai T +6 more
europepmc +1 more source
A deterministic model of the effect of electric field on chemotherapeutics delivery into a tumor [PDF]
, 2017 Achenie, Luke, Moarefian, Maryam
core +1 more source