Results 111 to 120 of about 439,053 (379)
The crystal structures of UMG‐SP2, a metagenome‐derived urethanase that degrades polyurethane, have been solved at high resolution in both ligand‐free and ligand‐bound forms with an amidase inhibitor or a small carbamate. Structure‐guided engineering of UMG‐SP2 improves the understanding of polyurethane degradation mechanisms and generates enzyme ...
Zhishuai Li+19 more
wiley +1 more source
Objective To determine the presence of glycosaminoglycans in the extracellular matrix of connective tissue from neoplastic and non-neoplastic colorectal tissues, since it has a central role in tumor development and progression.
Ana Paula Cleto Marolla+5 more
doaj +1 more source
The Gap Sampler: A Versatile Microfluidic Autosampler for Electrospray Ionization Mass Spectrometry
Microfluidic autosamplers for electrospray ionization mass spectrometry (ESI-MS) are of major importance when using ESI-MS as a high-throughput and low sample consumption analytical method.
Jerome Kaeslin
doaj +1 more source
Transfer conditions and transmission bias in capillaries of vacuum interfaces [PDF]
A detailed study of the transfer of ions in transfer capillaries of electrospray ion sources is presented. The laminar flow field for various capillary sizes and wall temperatures is calculated. It forms the base of ion transfer simulation of a large number of ions with space charge.
arxiv +1 more source
Recent advances in expanding the coverage of the lipidome [PDF]
The lipidome comprises a large array of molecules with diverse physicochemical properties. Lipids are structural components of cells, act as a source of energy, and function as signaling mediators.
Kamphorst, Jurre J., Tumanov, Sergey
core +1 more source
Network‐based risk stratification of people living with HIV (PWH) on prolonged therapy using multi‐omics data identifies 44% of the patients are at risk of immunometabolic complications. A senescence‐associated myeloid cell‐driven plasma microenvironment drives immunometabolic dysregulation in at‐risk PWH.
Flora Mikaeloff+32 more
wiley +1 more source
Molecular Dynamics Simulation of Sympathetic Crystallization of Molecular Ions [PDF]
It is shown that the translational degrees of freedom of a large variety of molecules, from light diatomic to heavy organic ones, can be cooled sympathetically and brought to rest (crystallized) in a linear Paul trap. The method relies on endowing the molecules with an appropriate positive charge, storage in a linear radiofrequency trap, and ...
arxiv +1 more source
Electrospray Systems And Methods [PDF]
Electrospray systems, electrospray structures, removable electrospray structures, methods of operating electrospray systems, and methods of fabricating electrospray systems, are disclosed.Georgia Tech Research ...
core
Determination of parabens in human urine by liquid chromatography coupled with electrospray ionization tandem mass spectrometry [PDF]
A simple and sensitive method was developed for the simultaneous determination of methyl, ethyl,n-propyl,n-butyl, and benzyl parabens in human urine by liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS).
Fu, Jiamo+6 more
core +1 more source
High‐throughput proteoform imaging (HTPi) is established by combining matrix‐assisted laser desorption ionization mass spectrometry imaging and high‐sensitivity region‐specific top‐down proteomic analysis. HTPi enables the generation of annotated proteoform images with exceptional precision, high throughput, and deep coverage, showing distinct spatial ...
Yue Sun+8 more
wiley +1 more source