Results 91 to 100 of about 2,688,547 (318)
Utility analyses of AVITI sequencing chemistry
Background DNA sequencing is a critical tool in modern biology. Over the last two decades, it has been revolutionized by the advent of massively parallel sequencing, leading to significant advances in the genome and transcriptome sequencing of various ...
Silvia Liu +12 more
doaj +1 more source
Objectives: Omadacycline is an aminomethylcycline (tetracycline class) antibacterial approved by the United States Food and Drug Administration (2018) for treatment of adults with acute bacterial skin and skin structure infection (ABSSSI) and community ...
Michael D. Huband +6 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Frontier Elements: Connections with f-Elements [PDF]
In the last decade organo-f-element chemistry has developed almost explosively. Especially organometallic compounds with carbocyclic ligands of the cyclopentadienyl type (Cp = η5-C5H5, Cp* = η5-C5(CH3)5, and other substituted cyclopentadienyls) have attracted a great deal of attention.
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Trend statistics in data processing for technical diagnostics systems
Probabilistic characteristics and the conditions for applying the Halda–Abbe criterion to detect trend dependencies in time series data within technical diagnostics systems are analyzed. An assessment is carried out of the influence of sample correlation,
V. F. Mirgorod, G. S. Ranchenko
doaj
Increasing rates of antimicrobial resistance require additional safe and effective options for managing difficult-to-treat infections. SPR206 is a next-generation polymyxin with improved in vivo safety profiles.
Gina M. Morgan +5 more
doaj +1 more source
Stress analysis of thin and thick plates on elastic foundations using boundary and finite element methods [PDF]
In this work an attempt has been made to derive a full finite element and boundary element theory for the analysis of thin and thick plates on elastic foundations. A new high order shear finite element capable of the analysis of thin thick plates has
Al-Hosani, Khaleel Ibrahim Abdulla
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Merging of 4 or 5 elements with n elements
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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