Results 101 to 110 of about 2,688,547 (318)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Finite and infinite element method applied to water wave diffraction problems [PDF]

open access: yes, 1999
In this work, three types of infinite elements are developed to solve the problem of linear water wave diffraction by objects in a 2D unbounded domain. The infinite elements, which model the far field wave potential stretching to infinity, are coupled to
Baghbani, A., Baghbani, Alireza
core  

Stress intensity factors computation for bending plates with extended finite element method [PDF]

open access: yes, 2012
The modelization of bending plates with through-the-thickness cracks is investigated. We consider the Kirchhoff–Love plate model, which is valid for very thin plates.
Salaün, Michel   +2 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

In Vitro Antimicrobial Activity of Ceftobiprole and Comparator Agents Against Streptococcus pneumoniae Responsible for Lower Respiratory Tract Infections in the United States (2016–2020), Including Resistant Subsets and Select Serotypes

open access: yesAntibiotics
Background: Ceftobiprole is an advanced-generation cephalosporin approved in Europe in 2013 for various indications, and in the United States (US) in 2024 for community-acquired bacterial pneumonia (CABP), acute bacterial skin and skin structure ...
Helio S. Sader   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Optimisations for quadrature representations of finite element tensors through automated code generation

open access: yes, 2009
We examine aspects of the computation of finite element matrices and vectors that are made possible by automated code generation. Given a variational form in a syntax that resembles standard mathematical notation, the low-level computer code for building

core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Thermoelectric performance enhancement of environmentally‐friendly SrTiO3 epitaxial films by hydrogen substitution

open access: yesEcoEnergy
Developing high‐efficiency and environmentally‐friendly thermoelectric materials has been a significant challenge. Conventional thermometric materials consist of heavy (toxic) elements to reduce thermal conductivity (κ), while we demonstrated light ...
Masatoshi Kimura   +6 more
doaj   +1 more source

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