Results 171 to 180 of about 2,688,547 (318)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Finite element multistep multideriavative schemes for parabolic equations

open access: yes, 1976
The linear, homogeneous, parabolic equation is solved by applying finite element discretizations in space and A0 —stable, linear multistep, multiderivative (L.M.S.D.) methods in time. Such schemes are unconditionally stable. An error analysis establishes
Moore, P
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Configurable Er-doped core-pumped multi-element fiber amplifier

open access: yes
We demonstrated an Erbium-doped multi-element-fiber amplifier extending the bandwidth at shorter wavelengths in C-band. Each fiber-element provides a maximum gain of 36dB and NF <4dB.
Thipparapu, N.K.   +3 more
core  

Finite element analysis of groundwater contamination

open access: yes, 1990
Includes bibliographical references.The purpose of this study was to develop a computational Finite Element model, validated by experimentation, to assist in the understanding of groundwater contamination problems.
Mahomed, N
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

A new continuum based non-linear finite element formulation for modeling of dynamic response of deep water riser behavior

open access: yes, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The principal objective of this investigation is to develop a nonlinear continuum based finite element formulation to examine dynamic response of flexible ...
Hosseini Kordkheili, Seyed Ali
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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