Results 61 to 70 of about 17,144 (192)

Polyphenol dietary supplementation prevents inflammation‐induced muscle atrophy in a zebrafish (Danio rerio) model

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Diet‐induced inflammation is a major cause of muscle degeneration impacting human and animal health. Owing to their anti‐inflammatory and antioxidant properties, polyphenols have attracted considerable interest as feed additives.
Graziella Orso, Monica Matuozzo, Mariapina Rocco, Seyed Hossein Hoseinifar, Ghasem Ashouri, Andrea Scaloni, Marina Paolucci, Chiara D'Ambrosio, Roberta Imperatore   +8 more
wiley   +1 more source

Vaccarin Improves Myocardial Ischemia–Reperfusion Injury by Attenuating Oxidative Stress and Ferroptosis Through Reducing NOX4‐Modulated JAK2/STAT3 Pathway Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vaccarin is a naturally occurring flavonoid glycoside with cardioprotective properties; however, its involvement in myocardial ischemia–reperfusion (MI/R) injury remains poorly defined. We herein investigated whether vaccarin protects cardiomyocytes from MI/R‐induced dysfunction in vivo and in vitro and examined the associated molecular ...
Han Yang, Mi Zhou, Feng‐Cai Zhang
wiley   +1 more source

Protective effect of ellagic acid against angiotensin II-induced cardiomyocyte hypertrophy in H9c2 myocardial cells: Role of calcineurin/NFAT pathway

Journal of Medicinal Plants, 2021
Background: Ellagic acid, a major ellagitannin found in pomegranate extract, might be an attractive natural and safe bioactive compound for prevention of cardiac hypertrophy in many pathological conditions that are associated with elevated circulating ...
Firouzeh Asadi, Ali Razmi, Foad Ghazizadeh, Massoumeh Shafiei   +3 more
doaj  

In Vivo Metabolite Profiling of a Purified Ellagitannin Isolated from Polygonum capitatum in Rats

Molecules, 2016
Ellagitannin is a common compound in food and herbs, but there are few detailed studies on the metabolism of purified ellagitannins. FR429 is a purified ellagitannin with antitumor potential, which is from Polygonum capitatum Buch.-Ham.ex D. Don.
Jing-Yi Ma, Xuelin Zhou, Jie Fu, Chi-Yu He, Ru Feng, Min Huang, Jia-Wen Shou, Zhen-Xiong Zhao, Xiao-Yang Li, Luye Zhang, Yang-Chao Chen, Yan Wang   +11 more
doaj   +1 more source

Accuracy of Factor VIII Assays for Measuring Damoctocog Alfa Pegol: A Comparative Analysis

Haemophilia, EarlyView.
ABSTRACT Introduction Accurate monitoring of treatment with modified factor VIII products remains challenging, due to known variability in assay performance across different laboratory methods and reagents. For the extended half‐life product Damoctocog alfa pegol discrepancies have been reported.
Judith C. A. Cluitmans, Piet Meijer, Sanna R. Rijpma, An K. Stroobants   +3 more
wiley   +1 more source

Effects of DX-9065a, an Inhibitor of Factor Xa, on Ellagic Acid-Induced Plantar Skin Thrombosis Assessed in Tetrodotoxin- and Nω-Nitro-LArginine-Treated Rats

Journal of Pharmacological Sciences, 2003
Effects of DX-9065a ((+)-2S-2-[4-[[(3S)-1-acetimidoyl-3-pyrrolidinyl]oxy]phenyl]-3-[7-amidino-2-naphthyl]propanoic acid hydrochloride pentahydrate), a dibasic propanoic acid and an inhibitor of factor Xa, were compared with those of argatroban, a low ...
Daisuke Chino, Yukiyoshi Fujita, Kunio Ishii, Koichi Nakayama   +3 more
doaj   +1 more source

(Poly)phenols: Mechanisms of action and efficacy of contemporary supplements for exercise recovery and performance

Experimental Physiology, EarlyView.
Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
wiley   +1 more source

Phytochemical Characterization of Extracts From Aesculus hippocastanum L. Seeds and Quantification of Saponins Using HPLC‐DAD and a Novel Tensiometric Approach

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Aesculus hippocastanum L. seed extracts prepared according to pharmacopeial methods were comprehensively characterized using HPLC‐DAD‐ESI‐MSn and GC‐MS. Furthermore, a novel bubble pressure tensiometric approach and an HPLC‐DAD method were employed for the quantitative analysis of surface‐active components.
Khadijeh Nosrati Gazafroudi, Rieka Dreher, Morwen Liebscher, Peter Lorenz, Rolf Daniels, Florian C. Stintzing, Dietmar R. Kammerer   +6 more
wiley   +1 more source

Bioactive Properties of Achillea biserrata M.Bieb. Extracts: Phytochemical Analysis, Antioxidant Activity, Target Enzyme Inhibition, and Cytotoxic Effects

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Integrated evaluation of Achillea biserrata extracts combining LC‐MS/MS phytochemical profiling, antioxidant, enzyme inhibitory, and antiproliferative assays with multivariate chemometric analyses (Pearson correlation, PCA, hierarchical clustering, and PLS regression), revealing phytochemicals associated with the observed biological activities (The ...
Zühal Bayrakçeken Güven, Mustafa Abdullah Yilmaz, Huseyin Inceer   +2 more
wiley   +1 more source

Pharmacokinetics and Tissue Distribution in Rats After Oral Administration of Tibetan Medicine Wuwei Leze Powder

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Wuwei Leze Powder (WLP), a classic Tibetan medicine for rheumatoid arthritis, is orally administered and undergoes extensive absorption and metabolism in rats. A total of 56 plasma constituents, including 21 prototypes and 35 metabolites, are identified.
Ping Wang, Peng Wang, YiRui Wu, ShuiYing Wu, HuiJuan Xu, WenYu Yang, Ya Tu, Chuan Liu   +7 more
wiley   +1 more source