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Cell type-dependent effects of ellagic acid on cellular metabolism
Biomedicine and Pharmacotherapy, 2018 Ellagic acid is a botanical polyphenol which has been shown to have numerous effects on cellular function. Ellagic acid can induce apoptosis and inhibit the proliferation of various cancer cell types in vitro and in vivo.
Pramod K Dash, Darren Boehning
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The metabolism of ellagic acid in the rat
Xenobiotica, 19801. Following oral administration of ellagic acid to the rat, 10% of the dose was excreted as 3,8-dihydroxy-6H-dibenzo[b,d]pyran-6-one in urine and faeces. A second metabolite was detected in urine and faeces but not identified. Both metabolites were of microfloral origin, as their formation was not observed in germ-free rats but was demonstrated when ...
B, Doyle, L A, Griffiths
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Ellagitannins, ellagic acid and vascular health
Molecular Aspects of Medicine, 2010Hydrolysable tannins are phenolic phytochemicals that show high antioxidant and free-radical scavenging activities. For this reason their potential effects preventing oxidative related diseases, such as cardiovascular diseases, have been largely studied.
Mar, Larrosa +3 more
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Neuroprotective Potential of Ellagic Acid: A Critical Review
Advances in Nutrition, 2021Ellagic acid (EA) is a dietary polyphenol present in various fruits, vegetables, herbs, and nuts. It exists either independently or as part of complex structures, such as ellagitannins, which release EA and several other metabolites including urolithins following absorption.
Ashutosh Gupta +5 more
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Spectrofluorimetric determination of ellagic acid in brandy
Food Chemistry, 2012Two spectrofluorimetric methods have been developed for the rapid determination of ellagic acid. The first method is based on the complex formation between ellagic acid and borax in methanol solution. The fluorescence of the complex is monitored at an emission wavelength of 456nm with excitation at 383nm.
Jana, Sádecká, Jana, Tóthová
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Reaction between Ellagic Acid and an Ultimate Carcinogen
Journal of Chemical Information and Modeling, 2005The reaction coordinate between a typical ultimate carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide (BPDE) and ellagic acid, a proven chemopreventive agent active against cancers caused by polycyclic aromatic hydrocarbons (PAHs), was examined by density functional theory (DFT) and semiempirical MO calculations, and activation energy was calculated.
Philippe Huetz +2 more
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Terahertz spectrum of ellagic acid
2009 34th International Conference on Infrared, Millimeter, and Terahertz Waves, 2009The absorption and refractive index of ellagic acid in the range of 0.2–2.4 THz have been measured by THz-TDS. It is found that the ellagic acid has the fingerprint absorption in this frequency region. The vibration absorption spectrum of the single molecule of ellagic acid between 0.2 and 2.4 THz is simulated based on the Density Functional Theory ...
Meng Wu, Guozhong Zhao, Cunlin Zhang
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ABORTION IN MICE INDUCED BY ELLAGIC ACID
Acta Pathologica Microbiologica Scandinavica Section A Pathology, 1971Ellagic acid was injected intravenously into mice at day 8, 12, or 16 of pregnancy. In all animals given this treatment there was an increased frequency of abortion. Platelet‐fibrin masses were found in the lungs, in the great majority of the mice given ellagic acid at day 16 of gestation.
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Action of ellagic acid on the melanin biosynthesis pathway
Journal of Dermatological Science, 2016Tyrosinase is an enzyme involved in the first steps of the melanogenesis process. It catalyzes the hydroxylation of monophenols to o-diphenols and the oxidation of the latter to o-quinones. Ellagic acid (EA) is a phenolic compound which has been described as a tyrosinase inhibitor and is used in the cosmetic industry as a whitening agent.
Carmen Vanessa, Ortiz-Ruiz +4 more
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The Control of Bleeding in Splenectomized Animals by Ellagic Acid
Thrombosis and Haemostasis, 1967Summary1. Blood loss after splenectomy was reduced significantly by i. v. injection of ellagic acid.2. The duration of bleeding was also shortened significantly.3. There were no obvious toxic manifestations and no evidence of thrombosis.
D, Agostino, E E, Cliffton
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