Results 11 to 20 of about 6,417 (157)

Stepwise LCST-Type Phase Separation in Mixtures of Short-Chain Elastin-Like Peptides With Minimal Structural Differences. [PDF]

Biopolymers
Small differences in chain‐length or topology induce stepwise phase separation in short‐chain ELP mixtures. ABSTRACT Elastin‐like peptides (ELPs) comprise repetitive pentapeptide sequences and exhibit liquid–liquid phase separation through lower critical solution temperature‐type behavior.
Tanaka N, Suyama K, Mai E, Nose T.
europepmc   +2 more sources

Bet v 1-displaying elastin-like polypeptide nanoparticles induce a strong humoral and weak CD4+ T-cell response against Bet v 1 in a murine immunogenicity model

Frontiers in Immunology, 2022
There is growing concern about the toxicity of colloidal aluminum salts used as adjuvants in subcutaneous allergen immunotherapy (SCIT). Therefore, alternative adjuvants and delivery systems are being explored to replace alum in SCIT. We applied micellar
Jolinde van Strien, Hans Warmenhoven, Hans Warmenhoven, Adrian Logiantara, Max Makurat, Lorenz Aglas, Athanasios Bethanis, Romain Leboux, Leonie van Rijt, J. Andrew MacKay, Johannes W. van Schijndel, Gregory Schneider, René Olsthoorn, Wim Jiskoot, Ronald van Ree, Ronald van Ree, Alexander Kros   +16 more
doaj   +1 more source

Network Pharmacology Combined with an Experimental Validation Study to Reveal the Effect and Mechanism of Eucommia ulmoides Leaf Polysaccharide against Immunomodulation

Foods, 2023
In the present study, the immuno-enhancing effect of Eucommia ulmoides leaf polysaccharide (ELP) was investigated in immunosuppressed mice induced by cyclophosphamide (CTX). To evaluate the immune enhancement mechanism of ELP, the immunoregulation effect
Enhui Cui, Pan Tang, Xiaoyan Zhu, Mengyuan Lv, Shuai Wang, Yuhuan Xue, Cixia Li, Shanting Zhao   +7 more
doaj   +1 more source

Elastin-like Polypeptide Hydrogels for Tunable, Sustained Local Chemotherapy in Malignant Glioma

Pharmaceutics, 2022
Glioblastoma (GBM) is a primary brain tumor that carries a dismal prognosis, which is primarily attributed to tumor recurrence after surgery and resistance to chemotherapy. Since the tumor recurrence appears near the site of surgical resection, a concept
Sonja Dragojevic, Lindsay Turner, Pallabi Pal, Amol V. Janorkar, Drazen Raucher   +4 more
doaj   +1 more source

Relationship between effective lens position and axial position of a thick intraocular lens. [PDF]

PLoS ONE, 2018
PurposeTo discuss the impact of intraocular lens-(IOL)-power, IOL-thickness, IOL-shape, corneal power and effective lens position (ELP) on the distance between the anterior IOL vertex (ALP) of a thick IOL and the ELP of its thin lens equivalent.MethodsWe
Simon Schröder, Achim Langenbucher
doaj   +1 more source

Construction of a Collagen-like Protein Based on Elastin-like Polypeptide Fusion and Evaluation of Its Performance in Promoting Wound Healing

Molecules, 2023
In the healing of wounds, human-like collagen (hCol) is essential. However, collagen-based composite dressings have poor stability in vivo, which severely limits their current therapeutic potential.
Yingli Chen, Yuanyuan Wu, Fengmin Xiong, Wei Yu, Tingting Wang, Jingjing Xiong, Luping Zhou, Fei Hu, Xianlong Ye, Xinmiao Liang   +9 more
doaj   +1 more source

Elastin-like polypeptide modified silk fibroin porous scaffold promotes osteochondral repair

Bioactive Materials, 2021
Silk fibroin (SF) is considered biocompatible and biodegradable for osteochondral repair. However, it lacks a bioactive domain for cell adhesion, proliferation and differentiation, limiting its therapeutic efficacy.
Zhuoyue Chen, Qiang Zhang, Hongmin Li, Qi Wei, Xin Zhao, Fulin Chen   +5 more
doaj   +1 more source

Application of Bio-Active Elastin-like Polypeptide on Regulation of Human Mesenchymal Stem Cell Behavior

Biomedicines, 2022
Regenerative medicine using stem cells offers promising strategies for treating a variety of degenerative diseases. Regulation of stem cell behavior and rejuvenate senescence are required for stem cells to be clinically effective.
Vijaya Sarangthem, Harshita Sharma, Mohini Mendiratta, Ranjit Kumar Sahoo, Rang-Woon Park, Lalit Kumar, Thoudam Debraj Singh, Sujata Mohanty   +7 more
doaj   +1 more source

Therapeutic Effect of IL-4 Receptor-Targeting Pro-Apoptotic Peptide (AP1-ELP-KLAK) in Glioblastoma Tumor Model

International Journal of Nanomedicine, 2021
Vijaya Sarangthem,1,2,* Aena Yi,1,* Yunjae Kim,1 Alnawaz Rehemtulla,3 Byung-Heon Lee,1 Young Hyun Jeon,4 Thoudam Debraj Singh,5 Rang-Woon Park1 1Department of Biochemistry and Cell Biology, School of Medicine, and Cell & Matrix Research Institute,
Sarangthem V, Yi A, Kim Y, Rehemtulla A, Lee BH, Jeon YH, Singh TD, Park RW   +7 more
doaj  

Endolymphatic Potential Measured From Developing and Adult Mouse Inner Ear

Frontiers in Cellular Neuroscience, 2020
The mammalian inner ear has two major parts, the cochlea is responsible for hearing and the vestibular organ is responsible for balance. The cochlea and vestibular organs are connected by a series of canals in the temporal bone and two distinct ...
Yi Li, Huizhan Liu, Xiaochang Zhao, David Z. He   +3 more
doaj   +1 more source