Results 141 to 150 of about 936,605 (354)
Free energy of multicomponent embryo formation [PDF]
arXiv, 2002 An expression for the free energy of embryo formation is constructed and analyzed. The Gibbs dividing surfaces method is used to attain a coincidence between Laplace formula for critical embryo and integral definitions of concenterations inside the embryo. A global structure of free energy is analyzed and some useful properties are extracted.
arxiv
Automated Measurements of Key Morphological Features of Human Embryos for IVF [PDF]
arXiv, 2020 A major challenge in clinical In-Vitro Fertilization (IVF) is selecting the highest quality embryo to transfer to the patient in the hopes of achieving a pregnancy. Time-lapse microscopy provides clinicians with a wealth of information for selecting embryos.
arxiv
Regulation of Microtubule Dynamics in Axon Regeneration: Insights from C. elegans. [PDF]
, 2016 The capacity of an axon to regenerate is regulated by its external environment and by cell-intrinsic factors. Studies in a variety of organisms suggest that alterations in axonal microtubule (MT) dynamics have potent effects on axon regeneration.
CHISHOLM, Andrew, Tang, Ngang
core +2 more sources
Advanced Science, EarlyView.A modular endosomal escape system boosts transfection efficiency of a DNA delivery agent. This system comprises a phospholipase fused to a split‐calbindin domain and a nanobody targeting CD9. In the extracellular space, the phospholipase is tightly bound to protein‐DNA complexes, released within endosomes at low calcium concentrations and recruited to ...
Alexander Klipp +5 more
wiley +1 more source
Sex-specific DNA-replication in the early mammalian embryo
Nature CommunicationsThe timing of DNA replication in mammals is crucial for minimizing errors and influenced by genome usage and chromatin states. Replication timing in the newly formed mammalian embryo remains poorly understood.
Jason Alexander Halliwell +5 more
doaj +1 more source
Zebrafish Pou5f1‐dependent transcriptional networks in temporal control of early development
Molecular Systems Biology, 2010 The transcription factor POU5f1/OCT4 controls pluripotency in mammalian ES cells, but little is known about its functions in the early embryo. We used time‐resolved transcriptome analysis of zebrafish pou5f1 MZspg mutant embryos to identify genes ...
Daria Onichtchouk +9 more
doaj +1 more source
Blood flow and the mammalian embryo [PDF]
, 2005 http://thesis.library.caltech.edu/2090/9/Jones_EAV_011305 ...
openaire +2 more sources
Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow. [PDF]
, 2017 The functions of blood flow in the morphogenesis of mammalian arteries and veins are not well understood. We examined the development of the dorsal aorta (DA) and the cardinal vein (CV) in Ncx1 -/- mutants, which lack blood flow due to a deficiency in a ...
Beckouche, Nathan +5 more
core +2 more sources
NF2 is Essential for Human Endoderm Development
Advanced Science, EarlyView.This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong +5 more
wiley +1 more source
Euromediterranean Biomedical Journal, 2018 Mitochondria are the most abundant organelles in mammalian oocytes and early embryos. The central role of mitochondria in the establishment of developmental competence of oocytes and early embryos come out from basic research in experimental models and ...
Manuel Belli
doaj +1 more source