Results 31 to 40 of about 212,225 (290)

The meganuclease I-SceI containing nuclear localization signal (NLS-I-SceI) efficiently mediated mammalian germline transgenesis via embryo cytoplasmic microinjection. [PDF]

PLoS ONE, 2014
The meganuclease I-SceI has been effectively used to facilitate transgenesis in fish eggs for nearly a decade. I-SceI-mediated transgenesis is simply via embryo cytoplasmic microinjection and only involves plasmid vectors containing I-SceI recognition ...
Yong Wang, Xiao-Yang Zhou, Peng-Ying Xiang, Lu-Lu Wang, Huan Tang, Fei Xie, Liang Li, Hong Wei   +7 more
doaj   +1 more source

Modeling mammalian gastrulation with embryonic stem cells

, 2017
Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the physical and ...
Amita, Arnold, Azioune, Bauwens, Bedzhov, Ben-Haim, Bernardo, Blin, Bolouri, Chambers, Coucouvanis, Dunn, Engler, Etoc, Farin, Gjorevski, Green, Gurdon, Harrison, Heemskerk, Heemskerk, Horii, Lee, Lei, Li, Lippmann, Loh, Meinhardt, Meinhardt, Mendjan, Migeotte, Müller, Nakamura, Nallet-Staub, Nemashkalo, Nemashkalo, Nowotschin, Pagliuca, Peerani, Perea-Gomez, Przybyla, Qin, Ranga, Rosowski, Saka, Sasai, Schohl, Shao, Shao, Simunovic, Sorre, Sun, Tang, ten Berge, Teo, Tewary, Théry, Turing, Turner, Turner, van den Brink, Warmflash, Wilson, Xu, Yang, Yu   +65 more
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Radial glia in the proliferative ventricular zone of the embryonic and adult turtle, Trachemys scripta elegans. [PDF]

, 2014
To better understand the role of radial glial (RG) cells in the evolution of the mammalian cerebral cortex, we investigated the role of RG cells in the dorsal cortex and dorsal ventricular ridge of the turtle, Trachemys scripta elegans.
Clinton, Brian K, Cunningham, Christopher L, Kriegstein, Arnold R, Martínez-Cerdeño, Verónica, Noctor, Stephen C   +4 more
core   +1 more source

The p66(Shc) adaptor protein controls oxidative stress response in early bovine embryos. [PDF]

PLoS ONE, 2014
The in vitro production of mammalian embryos suffers from high frequencies of developmental failure due to excessive levels of permanent embryo arrest and apoptosis caused by oxidative stress.
Dean H Betts, Nathan T Bain, Pavneesh Madan   +2 more
doaj   +1 more source

Erythroid development in the mammalian embryo [PDF]

Blood Cells, Molecules, and Diseases, 2013
Erythropoiesis is the process by which progenitors for red blood cells are produced and terminally differentiate. In all vertebrates, two morphologically distinct erythroid lineages (primitive, embryonic, and definitive, fetal/adult) form successively within the yolk sac, fetal liver, and marrow and are essential for normal development. Red blood cells
Margaret H, Baron, Andrei, Vacaru, Johnathan, Nieves   +2 more
openaire   +2 more sources

Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily [PDF]

, 2008
Background: Drosophila has six receptor protein tyrosine phosphatases (RPTPs), five of which are expressed primarily in neurons. Mutations in all five affect axon guidance, either alone or in combination.
Bahri, Sami, Jeon, Mili, Nguyen, Huong, Zinn, Kai   +3 more
core   +4 more sources

Asynchronous mouse embryo polarization leads to heterogeneity in cell fate specification

eLife
The first lineage allocation in mouse and human embryos separates the inner cell mass (ICM) from the outer trophectoderm (TE). This symmetry-breaking event is executed through polarization of cells at the 8 cell stage and subsequent asymmetric divisions,
Adiyant Lamba, Meng Zhu, Maciej Meglicki, Sylwia Czukiewska, Lakshmi Balasubramaniam, Ron Hadas, Nina Weishaupt, Ekta M Patel, Yu Hua Kavanagh, Ran Wang, Naihe Jing, Magdalena Zernicka-Goetz   +11 more
doaj   +1 more source

Epigenetic regulation in mammalian preimplantation embryo development

Reproductive Biology and Endocrinology, 2009
Preimplantation embryo development involves four stages: fertilization, cell cleavage, morula and blastocyst formation. During these stages, maternal and zygotic epigenetic factors play crucial roles.
Shi Lingjun, Wu Ji
doaj   +1 more source

Reorganization, specialization, and degradation of oocyte maternal components for early development

Reproductive Medicine and Biology, 2023
Background Oocyte components are maternally provided, solely determine oocyte quality, and coordinately determine embryo quality with zygotic gene expression.
Yuhkoh Satouh, Ken Sato
doaj   +1 more source

Molecular and cellular mechanisms underlying the evolution of form and function in the amniote jaw. [PDF]

, 2019
The amniote jaw complex is a remarkable amalgamation of derivatives from distinct embryonic cell lineages. During development, the cells in these lineages experience concerted movements, migrations, and signaling interactions that take them from their ...
A Abzhanov, A Abzhanov, A Abzhanov, A Baggiolini, A Baroffio, A Beverdam, A Chevallier, A Davidian, A del Rio, A Graham, A Graham, A Hosseini, A Rinon, A Roycroft, A Sharir, A Shellard, A Subramanian, AA Pitsillides, AE Adams, AE Merrill, AG Robling, AG Robling, AH Jheon, AJ Hughes, AL Romanoff, AL Tavares, ALP Tavares, AM Bailleul, AM Bailleul, AM Lucas, AS Pollard, AS Romer, AS Romer, AS Tucker, AS Tucker, AW Crompton, AW Crompton, B Christ, B McBratney-Owen, B Ruhin, BA Moore-Scott, BD Matthews, BF Eames, BF Eames, BF Kingsbury, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BK Hall, BL Pruitt, C Attanasio, C Gans, C Gegenbaur, C Holliday, C Mitgutsch, C Patterson, C Reichert, CI Lorda-Diez, CL Hammond, CS Le Lievre, CS Le Lièvre, CT Miller, CV Baker, CV Baker, CW Benkman, CW Benkman, D Hu, D Hu, D Hu, D Hu, D Noden, DD Davis, DE Clouthier, DG Wilkinson, DJ Evans, DL Stemple, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DM Noden, DR Carter, DR Cordero, E Berthet, E Blitz, E Blitz, E Dupin, E Gaupp, E Jarvik, E Theveneau, E Tzahor, E Tzahor, E Zelzer, EC Olesnicky Killian, EF Allin, EL Ealba, EM Sefton, EP Allis, EP Allis, EP Allis, ER Lankester, ES Goodrich, ES Goodrich, ES Russell, F Lescroart, F Liu, FJ Smith, FL Landacre, FV Jotereau, FW Chamberlain, G Andres, G Balooch, G Couly, G Couly, G Couly, G Kardon, G Kardon, G Köntges, G Wagner, G Zweers, GA Zweers, GA Zweers, GA Zweers, GB Muller, GF Couly, GF Couly, GM Morriss-Kay, GR de Beer, GR de Beer, GR de Beer, H Vinkka, HB Shaffer, HJ Chong, HL Hamilton, HL Szabo-Rogers, HP Shih, I Bothe, I Raizman, I Rot-Nikcevic, J Apostolakos, J Fang, J Grenier, J Hall, J Jeong, J Kahn, J Ruberte, J Stutzmann, JA Helms, JB Gross, JB Platt, JF Webb, JJ Baumel, JJ Schoenebeck, JJ Schoenebeck, JL Chang, JL Fish, JL Fish, JL Fish, JL Fish, JM Brito, JM Richman, JM Tabler, JN Thompson, JP Golding, JR Merida-Velasco, JR Merida-Velasco, JR Robbins, JS Kingsley, JW Kingsbury, K Hayashi, K Sheehan-Rooney, K Yasui, KC Woronowicz, KC Wu, KE Haworth, KJ Lamb, KK Smith, KK Smith, KK Smith, KK Smith, KS Thomson, KW Li, KW Tosney, L LeResche, L Olsson, L Ramage, LB Ruest, LS Gammill, LS Stone, LS Stone, M Bancroft, M Benjamin, M Bronner-Fraser, M Bronner-Fraser, M Hoso, M Jollie, M Jollie, M Jollie, M Jollie, M Linde-Medina, M Minoux, M Persson, M Qiu, M Qiu, M Sieber-Blum, M Simoes-Costa, M Takechi, M Tokita, M Tokita, MA Selleck, MA Shkoukani, MAJ Selleck, MJ Depew, MJ Depew, MJ Depew, MJ Depew, ML Martik, ML Moss, ML Moss, MM Dawson, MM Smith, MM Smith, MN Spyropoulos, MR Sanchez-Villagra, MR Sánchez-Villagra, MS Tyler, MSY Lee, N Anthwal, N Anthwal, N Anthwal, N Wang, NC Jones, NJ Giori, NM Young, NM Young, NN Soni, NS Bradley, O Campas, O Rieppel, OP Hamill, P Betancur, P Danaisawadi, P Hunt, P Kissel, P Kulesa, P Murray, P Murray, P Thorogood, P Wu, P Wu, PA Trainor, PA Trainor, PA Trainor, PA Trainor, PA Trainor, PA Trainor, PA Trainor, PD Henion, PDF Murray, PH Francis-West, PS Verma, PY Lwigale, R Cerny, R Derynck, R Diogo, R Luo, R Mallarino, R McBeath, R McLennan, R McLennan, R Owen, R Owen, R Presley, R Presley, R Sambasivan, R Sambasivan, R Schweitzer, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Schneider, RA Yuodelis, RC Garcez, RC Mootoosamy, RC Solem, RG Harrison, RG Northcutt, RG Northcutt, RJ Gorlin, RL Carroll, RL Zusi, RW Oppenheim, RW Oppenheim, RW Oppenheim, RW Shufeldt, S Alappat, S Amin, S Creuzet, S Dupont, S Ekanayake, S Hörstadius, S Kavumpurath, S Krispin, S Kuraku, S Kuratani, S Kuratani, S Kuratani, S Kuratani, S Kuratani, S Kuratani, S Kuratani, S Lamichhaney, S Lautenschlager, S Lautenschlager, S Murakami, S Shibata, S Tajbakhsh, S Thomopoulos, S Wadhwa, SC Ahlgren, SC Ahlgren, SH Lee, SH Reynolds, SJ Gould, SJ Mathew, SL Horowitz, SL Prescott, SL Washburn, SR Roberts, SW Herring, T Hems, T Hirasawa, T Kantomaa, T Maeda, T Mammoto, T Matsuoka, T Miyashita, T Rowe, T Sato, T Sauka-Spengler, T Sauka-Spengler, T Square, T Thomas, T Yoshida, TA Appel, TA Mitsiadis, TA Mitsiadis, TC Fitzgerald, TE Parsons, TG Boyd, TH Huxley, TH Huxley, TL Vincent, V Govindarajan, V Hamburger, V Hamburger, V Shone, VL Naples, W Maier, WA Beresford, WA Beresford, WE Reif, WF Van den Heuvel, WG Hall, WJ Moore, WJ Moore, WK Parker, WM McLeod, X Jiang, X Li, XL Tu, Y Hashimoto, Y Shigetani, Y Shigetani, Y Shwartz, Y Song, Y Sugimoto   +395 more
core   +1 more source