Results 21 to 30 of about 15,439,652 (357)
Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. [PDF]
, 2006 Vertebrates produce multiple chondroitin sulfate proteoglycans that play important roles in development and tissue mechanics. In the nematode Caenorhabditis elegans, the chondroitin chains lack sulfate but nevertheless play essential roles in embryonic ...
Bishop, Joseph R +4 more
core +2 more sources
Structure of the mammalian TRPM7, a magnesium channel required during embryonic development
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Ion channels are pore-forming proteins spanning biological membranes. Transient receptor potential ion channels are a subclass of ion channel proteins, characterized by nonselective permeability to cations such as sodium, calcium, magnesium,
J. Duan +9 more
semanticscholar +1 more source
Journal of Cell Biology, 2003 Mitochondrial morphology is determined by a dynamic equilibrium between organelle fusion and fission, but the significance of these processes in vertebrates is unknown.
Hsiuchen Chen +5 more
semanticscholar +1 more source
Developmental potential of aneuploid human embryos cultured beyond implantation
Nature Communications, 2020 Aneuploidy, abnormal chromosome number, is a major cause of early pregnancy loss. Here the authors determine the extent of post-implantation development of human embryos with common aneuploidies in culture, finding developmental arrest of monosomy 21 ...
Marta N. Shahbazi +11 more
doaj +1 more source
The role of spatial averaging in the precision of gene expression patterns [PDF]
, 2009 During embryonic development, differentiating cells respond via gene expression to positional cues from morphogen gradients. While gene expression is often highly erratic, embryonic development is precise. We show by theory and simulations that diffusion
Erdmann, Thorsten +2 more
core +3 more sources
Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development
Scientific Reports, 2019 Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1) plays an important role in RNA processing via in m6A modification of pre-mRNA or pre-miRNA.
Jeong-woo Kwon +3 more
semanticscholar +1 more source
Nature Communications, 2017 Liver and pancreas cells arise from a common endoderm progenitor in the embryo, but what regulates their cell fate is unclear. Here, the authors show that expression of the Three-Amino-acid-Loop-Extension (TALE) homeobox TG-interacting factor 2 (TGIF2 ...
Nuria Cerdá-Esteban +9 more
doaj +1 more source
Correlation with basic differentiation processes of neurons [PDF]
, 1991 The development of the spinal cord involves the proliferation of neurons, their migration to well-defined areas, fiber outgrowth and synapse formation. The present study was designed to correlate the spatiotemporal pattern of expression of synaptophysin,
Altman +37 more
core +2 more sources
The cis-regulatory dynamics of embryonic development at single cell resolution
Nature, 2017 Understanding how gene regulatory networks control the progressive restriction of cell fates is a long-standing challenge. Recent advances in measuring gene expression in single cells are providing new insights into lineage commitment.
D. Cusanovich +10 more
semanticscholar +1 more source
Embryonic POU5F1 is Required for Expanded Bovine Blastocyst Formation. [PDF]
, 2018 POU5F1 is a transcription factor and master regulator of cell pluripotency with indispensable roles in early embryo development and cell lineage specification.
Daigneault, Bradford W +3 more
core +2 more sources