Results 201 to 210 of about 123,304 (256)

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao   +4 more
wiley   +1 more source

The shared benefits of fallen fruits: A novel mechanism stabilizing a nursery pollination mutualism between Sambucus and kateretid beetles

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Understanding how cooperative interactions remain stable matters for biodiversity because many plants rely on specialist insects that can also impose reproductive costs. We studied the interaction between Sambucus sieboldiana and seed‐consuming Heterhelus beetles through detailed field observations and pollination experiments.
Suzu Kawashima   +3 more
wiley   +1 more source

Status and future of seed conservation of threatened plants in the post‐2020 era

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Ambitious targets have been set to backup seeds of threatened plants by the global strategy for plant conservation (GSPC), but it is unclear in how far these targets have been met and how seed collection should be organized to meet future challenges. Here, we provide an overview of the status of 44 countries in achieving seed conservation targets.
Andreas Ensslin   +130 more
wiley   +1 more source

COX5A promotes cell progression and cisplatin‐resistance by alleviating mitochondrial dysfunction in head and neck squamous cell carcinoma

open access: yesPrecision Medical Sciences, EarlyView.
COX5A promotes cell progression and cisplatin‐resistance and alleviates mitochondrial dysfunction. ISG15 shows a reversing role with COX5A. Targeting the COX5A‐mediated mitochondrial metabolic pathway may offer a novel therapeutic approach to enhance cisplatin sensitivity in HNSCC.
Nannan Guo   +7 more
wiley   +1 more source

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