Results 61 to 70 of about 123,304 (256)
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Fecundity and Embryonic Mortality in Pigs [PDF]
Development, 1954 ABSTRACT 863 female pigs, mostly sows discarded from commercial herds in East Anglia and sold for slaughter, were examined when killed and the condition of the reproductive tract was related to the animal’s reproductive history when it was known. The most frequent number of corpora lutea was 20, the average 19·6.
openaire +1 more source
Brazilian Journal of Poultry ScienceThis investigation was carried out to determine the effect of Essential Fatty Acids proportion (EFAs [n-6, n-3]) in feed through the mixture of soy, olive, canola or chia oil on EFA profile in eggs as well as productive and reproductive performance of ...
CB Castro-Tamayo +7 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
wiley +1 more source
Selected Traits of Hatched and Unhatched Eggs and Growth Performance of Yellow Japanese Quails
Brazilian Journal of Poultry ScienceThis study was carried out to investigate selected traits of hatched and unhatched eggs and chick growth performance of yellow Japanese quails (Coturnix japonica). Eggshell temperature at the time of transfer to the hatcher was higher in hatched eggs (38.
G Copur Akpinar, S Alasahan, T Ayasan
doaj +1 more source
Advanced Science, EarlyView.Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler +4 more
wiley +1 more source
The Journal of Poultry Science, 2005 These experiments were conducted to investigate the effects of egg storage position and injection of solutions into stored eggs on hatchability in chickens.
Anil Kr. Tiwary, Teruo Maeda
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen +18 more
wiley +1 more source
Advanced Science, EarlyView.This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen +7 more
wiley +1 more source
Uterine luminal fluid protein content in viable and non-viable Conceptuses in sheep
Revista Científica, 2012 During implantation, embryo survival depends on the availability of uterine and/or trophoblastic secreted molecules, including proteins. In order to determine possible differences in the protein profile of the uterine luminal fluid (ULF) adjacent to the ...
José Rodríguez Márquez +3 more
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