Dynamics of microRNA secreted via extracellular vesicles during the maturation of embryonic stem cell-derived retinal pigment epithelium. [PDF]
Pollalis D+15 more
europepmc +1 more source
Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei
Megan Munsie+5 more
openalex +1 more source
Embryonic stem cell self‐renewal pathways converge on the transcription factor Tfcp2l1
Shoudong Ye+3 more
semanticscholar +1 more source
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang+9 more
wiley +1 more source
A spinal and bulbar muscular atrophy (SBMA) disease-specific human embryonic stem cell (hESC) line, UMICHe002-A/UM197-1. [PDF]
Erliandri I+4 more
europepmc +1 more source
Suspended Tissue Open Microfluidic Patterning (STOMP)
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack+22 more
wiley +1 more source
Dissolution of ribonucleoprotein condensates by the embryonic stem cell protein L1TD1. [PDF]
Jin SW+4 more
europepmc +1 more source
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
Yangming Wang+4 more
semanticscholar +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Modeling vascular dynamics at the initial stage of endochondral ossification on a microfluidic chip using a human embryonic-stem-cell-derived organoid. [PDF]
Kesharwani A+7 more
europepmc +1 more source