Results 11 to 20 of about 354,563 (218)

MicroRNAs in embryonic stem cells [PDF]

Journal of Cellular Physiology, 2008
AbstractThe unique properties of embryonic stem cells (ESCs) to self‐renew indefinitely or to differentiate to any cell type have great potential for clinical applications in regenerative medicine. MicroRNAs (miRNAs) are emerging as important regulators of post‐transcriptional gene expression and have been implicated as crucial elements in regulating ...
Yulei, Wang, David N, Keys, Janice K, Au-Young, Caifu, Chen   +3 more
openaire   +2 more sources

Notch promotes neural lineage entry by pluripotent embryonic stem cells [PDF]

, 2006
A central challenge in embryonic stem (ES) cell biology is to understand how to impose direction on primary lineage commitment. In basal culture conditions, the majority of ES cells convert asynchronously into neural cells.
Smith, Austin G, Austin G Smith, Heavey Barry, Alexandra Benchoua, Benchoua, Alexandra, Smith, Austin,, Benchoua Alexandra, Sally Lowell, Smith Austin G, Lowell, Sally; id_orcid, Smith, Austin, G., Lowell Sally, Lowell, Sally, Heavey, Barry, Barry Heavey   +14 more
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ANGPTL8 accelerates liver fibrosis mediated by HFD-induced inflammatory activity via LILRB2/ERK signaling pathways

Journal of Advanced Research, 2023
Introduction: High calorie intake is known to induce nonalcoholic fatty liver disease (NAFLD) by promoting chronic inflammation. However, the mechanisms are poorly understood.
Zongli Zhang, Yue Yuan, Lin Hu, Jian Tang, Zhongji Meng, Longjun Dai, Yujiu Gao, Shinan Ma, Xiaoli Wang, Yahong Yuan, Qiufang Zhang, Weibin Cai, Xuzhi Ruan, Xingrong Guo   +13 more
doaj   +1 more source

Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells [PDF]

, 2006
Embryonic cortical neural stem cells apparently have a transient existence, as they do not persist in the adult cortex. We sought to determine the fate of embryonic cortical stem cells by following Emx1(IREScre); LacZ/EGFP double-transgenic murine cells ...
Seaberg, R.M., Cindi M. Morshead, Morshead, C.M., Kevin R. Jones, Gorski, J.A., Raewyn M. Seaberg, Etienne Labbé, Jessica A. Gorski, Attisano, L., Jones, K.R., Sandrine Willaime-Morawek, Willaime-Morawek, S., Labbé, E., van der Kooy, D., Claudia Batista, Batista, C., Angela Kam, Liliana Attisano, Derek van der Kooy   +18 more
core   +1 more source

Generation and characterization of erythroid cells from human embryonic stem cells and induced pluripotent stem cells : an overview [PDF]

, 2011
Because of the imbalance in the supply and demand of red blood cells (RBCs), especially for alloimmunized patients or patients with rare blood phenotypes, extensive research has been done to generate therapeutic quantities of mature RBCs from ...
Bönig, Halvard-Björn, Chang, Kai-Hsin, Kai-Hsin Chang, Thalia Papayannopoulou, Halvard Bonig, Papayannopoulou, Thalia   +5 more
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Monitoring cell line identity in collections of human induced pluripotent stem cells

Stem Cell Research, 2018
The ability to reprogram somatic cells into induced pluripotent stem cells (hiPSCs) has led to the generation of large collections of cell lines from thousands of individuals with specific phenotypes, many of which will be shared among different research
Raquel Sarafian, Mariana Morato-Marques, Juliana Borsoi, Lygia Veiga Pereira   +3 more
doaj   +1 more source

Embryonic Stem Cell.

Internal Medicine, 2001
Mouse embryonic stem (ES) cells are the cells that possess pluripotential differentiation activity into not only all somatic cells but also germ cells. Genetic alteration of mouse ES cells can be easily achieved and such genetic modification can be introduced into the animal, since ES cells are differentiated into germ cells in vivo.
SATO, Masatake, NAKANO, Toru
openaire   +3 more sources

Lentiviral manipulation of gene expression in human adult and embryonic stem cells [PDF]

, 2006
Human stem cells could revolutionize the field of medicine by providing a diverse range of cell types for tissue replacement therapies and drug discovery.
Joanne Crossley, Crossley, J., Andrew Godfrey, Takeuchi, Y., Clements, M.O., Boshoff, C., Godfrey, A., Mark O. Clements, Sam J. Wilson, Wilson, S.J., Yasu Takeuchi, Chris Boshoff   +11 more
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Genesis of embryonic stem cells [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003
Embryonic stem (ES) cells are permanent pluripotent stem cell lines established from pre–implantation mouse embryos. There is currently great interest in the potential therapeutic applications of analogous cells derived from human embryos.
Mia, Buehr, Austin, Smith
openaire   +2 more sources

Angiogenic potential of endothelial progenitor cells and embryonic stem cells [PDF]

, 2011
Background: Endothelial progenitor cells (EPCs) are implicated in a range of pathological conditions, suggesting a natural therapeutic role for EPCs in angiogenesis.
St John, Justin, Kelly, Richard, Kelly, RDW, Stuart Egginton, Rae, Peter, Richard DW Kelly, StJohn, JC, Peter C Rae, St. John, Justin C., Justin C St John, Rae, Peter C., Egginton, Stuart, Rae, PC, Egginton, S, Kelly, Richard D. W., St John, JC   +15 more
core   +1 more source