Results 41 to 50 of about 354,563 (218)

GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION.

open access: yes, 2013
Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Polgár, Zsuzsanna   +5 more
core   +1 more source

Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part I: Cellular characterization [PDF]

open access: yes, 2012
Embryonic stem cells derived from nuclear transfer embryos (ntESCs) are particularly valuable for regenerative medicine, as they are a patient-specific and histocompatible cell source for the treatment of varying diseases.
Julianna Kobolak   +13 more
core   +1 more source

Avian Embryonic Stem Cells [PDF]

open access: yes, 2006
Blastodermal cells derived from the area pellucida of a stage X (EG&K) embryo have the potential to contribute to the somatic tissues and the germ line when reintroduced into a stage X (EG&K) recipient embryo. This chapter describes a method to culture chicken embryonic stem (cES) cells derived from blastodermal cells. Within the first week of culture,
Marie-Cecile, van de Lavoir   +1 more
openaire   +2 more sources

ABI3BP promotes renal aging through Klotho-mediated ferroptosis

open access: yesJournal of Translational Medicine
The aging process of the kidneys is accompanied with several structural diseases. Abnormal fiber formation disrupts the balance of kidney structure and function, causing to end-stage renal disease and subsequent renal failure.
Ren Ji   +8 more
doaj   +1 more source

Effects of Alkaline Phosphatase, GATA, and BMP Expression on Three Populations of Cells: Spermatogonial Stem Cells, Embryonic Cells, and Embryonic Stem-Like Cells in Mice [PDF]

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2023
Background and Objective: Alkaline phosphatase, BMP, and GATA proteins are important factors in the process of spermatogenesis. This study aims to investigate the effect of alkaline phosphatase, GATA, and BMP expression on spermatogenic stem cells ...
Emad Reza, Hossein Azizi
doaj  

Signalling, cell cycle and pluripotency in embryonic stem cells

open access: yes, 2002
Pluripotent mouse embryonic stem (ES) cells can be expanded in large numbers in vitro owing to a process of symmetrical self-renewal. Self-renewal entails proliferation with a concomitant suppression of differentiation.
Burdon, Tom   +4 more
core   +1 more source

ANGPTL8 accelerates bone loss in diabetic mice by promoting osteoclastic differentiation and inhibiting osteoblastic differentiation through AMPK pathway-mediated metabolic reprogramming

open access: yesCellular and Molecular Life Sciences
Disruptions in energy metabolism within skeletal cells play a critical role in the pathogenesis of diabetic osteoporosis (DOP), primarily by affecting bone’s metabolic balance.
Peng Tuo   +12 more
doaj   +1 more source

Immunosuppression by Embryonic Stem Cells [PDF]

open access: yesStem Cells, 2007
AbstractEmbryonic stem cells or their progeny inevitably differ genetically from those who might receive the cells as transplants. We tested the barriers to engraftment of embryonic stem cells and the mechanisms that determine those barriers. Using formation of teratomas as a measure of engraftment, we found that semiallogeneic and fully allogeneic ...
Cody A, Koch   +2 more
openaire   +2 more sources

Trimethylamine N-oxide promotes the proliferation and migration of hepatocellular carcinoma cell through the MAPK pathway

open access: yesDiscover Oncology
Trimethylamine-n-oxide (TMAO) is a metabolite of intestinal flora following the consumption of phosphatidylcholine-rich foods. Clinical cohort studies have shown that plasma TMAO may be a risk factor for cancer development, including hepatocellular ...
Chunfang Zhou   +6 more
doaj   +1 more source

Porcine pluripotent stem cells: progress, challenges and prospects [PDF]

open access: yesFrontiers of Agricultural Science and Engineering, 2019
Pluripotent stem cells (PSCs) are characterized by their capacity for high self-renewal and multiple differentiation potential and include embryonic stem cells, embryonic germ cells and induced PSCs.
Jianyong HAN, Yi-Liang MIAO, Jinlian HUA, Yan LI, Xue ZHANG, Jilong ZHOU, Na LI, Ying ZHANG, Jinying ZHANG, Zhonghua LIU
doaj   +1 more source

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