Results 61 to 70 of about 354,563 (218)

Cortex- and striatum-derived neural stem cells produce distinct progeny in the olfactory bulb and striatum [PDF]

, 2008
Neural stem cells can be isolated from the mouse embryonic cortex but do not persist in the adult cortex. In contrast, neural stem cells from the striatal embryonic germinal zone persist in the adult subependyma.
Willaime-Morawek, S., Van der Kooy, D.
core   +1 more source

In ‌‌‌Vitro Differentiation of Mouse Embryonic Stem Cells into Lymphoid Lineage by Defined Growth Factors [PDF]

پیاورد سلامت, 2012
Background and Aim: Embryonic stem cells are identified with two unique characteristics. First, they can be maintained and expanded as pure populations of undifferentiated cells, a characteristic which is known as self renewal aspect of embryonic stem ...
Mina Soufi Zomorod, Gholamreaz Khamisipour, Saeid Abroun, Zahra Zonoubi, Abbas Haji Fathali, Masoud Soleimani, Saeid Kaviani, Majid Mossahebi Mohammadi   +7 more
doaj   +2 more sources

Ontological Differences in First Compared to Third Trimester Human Fetal Placental Chorionic Stem Cells [PDF]

, 2012
Human mesenchymal stromal/stem cells (MSC) isolated from fetal tissues hold promise for use in tissue engineering applications and cell-based therapies, but their collection is restricted ethically and technically.
Vanleene, Maximilien, George Bou-Gharios (139817), Moschidou Dafni, Gemma N Jones, Maximilien Vanleene (139811), George Bou-Gharios, Puga-Iglesias, Tamara-Isabel, Katarzyna Kuleszewicz, Sandra J. Shefelbine (139814), David, AL, Shefelbine, Sandra J., Fisk, NM, David Anna L., Moschidou, Dafni, Shefelbine Sandra J., Guillot, Pascale V., Bou-Gharios George, Gemma N. Jones (139797), Maximilien Vanleene, Fisk Nicholas M., Nicholas M Fisk, Shefelbine, SJ, De Coppi, Paolo, Puga-Iglesias, TI, Puga-Iglesias Tamara-Isabel, Katarzyna Kuleszewicz (139808), Paolo De Coppi (118582), Jones Gemma N., Bou-Gharios, G, Pascale V. Guillot (139827), Kuleszewicz Katarzyna, Anna L David, Vanleene, M, Kuleszewicz, K, David, Anna L., Sandra J Shefelbine, Fisk, Nicholas M., Dafni Moschidou, Paolo De Coppi, Bou-Gharios, George, Tamara-Isabel Puga-Iglesias, Pascale V Guillot, Jones, GN, Tamara-Isabel Puga-Iglesias (139805), Guillot, PV, De Coppi Paolo, Fisk, NM ; https://orcid.org/, Jones, Gemma N., Dafni Moschidou (139801), Guillot Pascale V., Kuleszewicz, Katarzyna, Moschidou, D, Vanleene Maximilien, Nicholas M. Fisk (139820), De Coppi, P, Anna L. David (139823)   +55 more
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Embryonic stem cell-derived hematopoietic stem cells [PDF]

Proceedings of the National Academy of Sciences, 2005
Despite two decades of studies documenting thein vitroblood-forming potential of murine embryonic stem cells (ESCs), achieving stable long-term blood engraftment of ESC-derived hematopoietic stem cells in irradiated mice has proven difficult. We have exploited theCdx-Hoxpathway, a genetic program important for blood development, to enhance the ...
Yuan, Wang, Frank, Yates, Olaia, Naveiras, Patricia, Ernst, George Q, Daley   +4 more
openaire   +2 more sources

Liver-specific expression of ANGPTL8 promotes Alzheimer’s disease progression through activating microglial pyroptosis

Journal of Neuroinflammation
Introduction Liver dysfunction contributes to Alzheimer’s disease (AD) pathogenesis, and evidence suggests that the liver is involved in amyloid β (Aβ) clearance, and regulates Aβ deposition in the brain.
Jiarui Wei, Lin Hu, Shufan Xu, Fan Yang, Fusheng Liao, Ying Tang, Xin Shen, Xiaoqiao Zhang, Xinggang Fang, Yifan Li, Li Ding, Zhuo Chen, Shanchun Su, Junhua Cheng, Yong Huang, Qian Chen, Daqing Ma, Qiufang Zhang, Xingrong Guo   +18 more
doaj   +1 more source

The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells

Cell & Bioscience, 2017
Increasing evidence indicates that embryonic stem cell specific microRNAs (miRNAs) play an essential role in the early development of embryo. Among them, the miR-290-295 cluster is the most highly expressed in the mouse embryonic stem cells and involved ...
Kai Yuan, Wen-Bing Ai, Lin-Yan Wan, Xiao Tan, Jiang-Feng Wu   +4 more
doaj   +1 more source

The epigenetic bivalency of core pancreatic β-cell transcription factor genes within mouse pluripotent embryonic stem cells is not affected by knockdown of the polycomb repressive complex 2, SUZ12.

PLoS ONE, 2014
This study assesses changes in activator and repressor modifications to histones associated with the core transcription factor genes most highly upregulated or downregulated in pancreatic β-cells relative to expression in an embryonic stem cell line ...
Jennifer C Y Wong, Michelle M Jack, Yan Li, Christopher O'Neill   +3 more
doaj   +1 more source

The King is Dead, Long Live the King: Entering A New Era of Stem Cell Research and Clinical Development

Journal of Translational Medicine, 2011
In mid November the biopharma industry was shocked by the announcement from Geron that they were ending work on embryonic stem cell research and therapy.
Ichim Thomas, Riordan Neil H, Stroncek David F   +2 more
doaj   +1 more source

Src Family Tyrosine Kinase Signaling in Mouse and Human Embryonic Stem Cells [PDF]

, 2013
Embryonic stem (ES) cells are derived from the inner cell mass of the blastocyst stage embryo and are characterized by self-renewal and pluripotency. Previous work has implicated the Src family of protein-tyrosine kinases (SFKs) in the self-renewal and ...
Zhang, Xiong
core  

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis [PDF]

, 2011
The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansion ...
Glenda J. Dickson, Pamela M. Corrigan, Freeburn, R.W., Robin W. Freeburn, Dickson, Glenda, Thompson, Alexander, Ramsey, Joanne, Helen Wheadon, Wheadon, H., Dickson, G.J., Edwina Dobbin, Alexander Thompson, Ramsey, J.M., Corrigan, P.M., Joanne M. Ramsey, Dobbin, E., Thompson, A.   +16 more
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