Results 71 to 80 of about 354,563 (218)

Pig Pluripotent Stem Cells as a Candidate for Biomedical Application

Journal of Animal Reproduction and Biotechnology, 2019
Stem cells are progenitor cells that are capable of self-renewal and differentiation into various cells. Especially, pluripotent stem cells (PSCs) have in vivo and in vitro differentiation capacity into three germ layers and can proliferate infinitely ...
Kwang-Hwan Choi, Chang-Kyu Lee
doaj   +1 more source

Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part II: Gene regulation [PDF]

, 2012
In a mouse model nuclear transfer embryo-derived embryonic stem cell lines (ntESCs) of various genetic backgrounds and donor cell types were compared with reference ESCs and analyzed comprehensively at molecular level as a second part of a larger study ...
Julianna Kobolak, Geißler, S., Mamo, S., Horsch, Marion, Horsch, M., Andras Dinnyes, Geissler, Sandra, Mamo, Solomon, Marion Horsch, Kobolak, J., Beckers, Johannes, Solomon Mamo, Kobolak, Julianna, Dinnyes, Andras, Beckers, J., Johannes Beckers, Sandra Geißler, Dinnyes, A.   +17 more
core   +1 more source

Mouse embryonic stem cells as a discovery tool in neurobiology [PDF]

, 2012
Mouse ES cells can recapitulate, under suitable tissue culture conditions, early events in neurogenesis. As wildtype or genetically modified ES cells can be grown in unlimited quantities, their differentiation into neurons represents an attractive model
Nikoletopoulou, Vassiliki
core   +1 more source

Distinct molecular profile and restricted stem cell potential defines the prospective human cranial neural crest from embryonic stem cell state

Stem Cell Research, 2020
Neural crest cells are an embryonic multipotent stem cell population. Recent studies in model organisms have suggested that neural crest cells are specified earlier than previously thought, at blastula stages.
Maneeshi S. Prasad, Rebekah M. Charney, Lipsa J. Patel, Martín I. García-Castro   +3 more
doaj   +1 more source

Embryonic Stem Cell Research

Voices in Bioethics, 2019
Voices in Bioethics, Vol 5 (2019)
openaire   +2 more sources

Recruitment of Oct4 protein to UV-damaged chromatin in embryonic stem cells. [PDF]

, 2011
BACKGROUND: Oct4 is a specific marker of embryonic stem cell (ESC) pluripotency. However, little is known regarding how Oct4 responds to DNA damage. Here, we investigated whether Oct4 recognizes damaged chromatin in mouse ESCs stably expressing GFP-Oct4.
Kozubek, Stanislav, Foltankova, Veronika, Stanislav Kozubek, Gabriela Šustáčková, Lenka Stixová, Stixová Lenka, Soňa Legartová, Bartova, Eva, Veronika Foltánková, Kozubek Stanislav, Bártová Eva, Legartová Soňa, Foltánková Veronika, Stixova, Lenka, Legartova, Sona, Eva Bártová, Sustackova, Gabriela, Šustáčková Gabriela   +17 more
core   +1 more source

The Liberation of Embryonic Stem Cells

PLoS Genetics, 2011
Mouse embryonic stem (ES) cells are defined by their capacity to self-renew and their ability to differentiate into all adult tissues including the germ line. Along with efficient clonal propagation, these properties have made them an unparalleled tool for manipulation of the mouse genome.
Kathryn Blair, Jason Wray, Austin Smith
openaire   +4 more sources

CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

Cell Death and Disease
Insufficient liver regeneration increases the risk of postoperative liver failure following liver transplantation or partial hepatectomy (PHx). Numerous growth factors and cytokines are related to liver regeneration; however, the underlying mechanisms ...
Qun Zhao, Jingyi Wu, Mengyuan Feng, Anjie Zhang, Liwei Fu, Jinglin Chen, Lian Li, Fangzhou Li, Tingting Li, Shu Jin, Shengbao Li, Xianjun Yu   +11 more
doaj   +1 more source

Network toxicology and molecular docking to investigate the mechanism of bisphenol A toxicity in human diabetic cardiomyopathy

Ecotoxicology and Environmental Safety
Bisphenol A (BPA), a ubiquitous endocrine-disrupting chemical, is widely used in polymers, plasticizers, and food packaging, raising significant concerns for human health. Growing evidence links BPA exposure to cardiovascular diseases, including diabetic
Bo Li, Xu Zhao, Yan Ding, Yi Zhang
doaj   +1 more source

A Bibliometric Analysis of Publications on Pluripotent Stem Cell Research [PDF]

Cell Journal, 2015
Objective: Human pluripotent stem cells are self-renewing cells with the ability to differentiate into a variety of cells and are viewed to have great potential in the field of regenerative medicine.
Changshuan L. Lin, Yuh-Shan Ho
doaj