Results 81 to 90 of about 354,563 (218)

Enhanced gene trapping in mouse embryonic stem cells

, 2008
Gene trapping is used to introduce insertional mutations into genes of mouse embryonic stem cells (ESCs). It is performed with gene trap vectors that simultaneously mutate and report the expression of the endogenous gene at the site of insertion and ...
Hansen, J., von Melchner, H., Ruiz Noppinger, Patricia, Wurst, W., Schnütgen, Frank, Floss, Thomas, Hansen, Jens, Horn, C., Ruiz Noppinger, P., Horn, Carsten, Lutz, M., Lutz, Marcus, Schnütgen, F., De-Zolt, Silke, De-Zolt, S., Wurst, Wolfgang, Melchner, Harald von (Prof. Dr.), Floß, T.   +17 more
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Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]

, 2009
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J, Aldskogius, Hakan, Wegner, M, Hjerling-Leffler, Jens, Kozlova, Elena N, Medvinsky, Alexander, Berens, C, Aldskogius, H, Kozlova, EN, Berens, Christian, Kanaykina, Nadezda, Sandelin, Martin, Schreiner, S, Wegner, Michael, Kanaykina, N, Sandelin, M, Liakhovitskaia, A, Medvinsky, A, Liakhovitskaia, Anna, Schreiner, Silke   +19 more
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Development and application of haploid embryonic stem cells

Stem Cell Research & Therapy
Haploid cells are a kind of cells with only one set of chromosomes. Compared with traditional diploid cells, haploid cells have unique advantages in gene screening and drug-targeted therapy, due to their phenotype being equal to the genotype.
Hai-Song Wang, Xin-Rui Ma, Yi-Hong Guo
doaj   +1 more source

Embryos, Clones, and Stem Cells: A Scientific Primer

The Scientific World Journal, 2004
This article is intended to give the nonspecialist an insight into the nuances of “clones”, cloning, and stem cells. It distinguishes embryonic and adult stem cells, their normal function in the organism, their origin, and how they are recovered to ...
Kenyon S. Tweedell
doaj   +1 more source

Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways.

PLoS ONE, 2009
Human embryonic stem cells have unique value for regenerative medicine, as they are capable of differentiating into a broad variety of cell types. Therefore, defining the signalling pathways that control early cell fate decisions of pluripotent stem ...
Ludovic Vallier, Thomas Touboul, Zhenzhi Chng, Minodora Brimpari, Nicholas Hannan, Enrique Millan, Lucy E Smithers, Matthew Trotter, Peter Rugg-Gunn, Anne Weber, Roger A Pedersen   +10 more
doaj   +1 more source

Neuronal induction and regional identity by co-culture of adherent human embryonic stem cells with chicken notochords and somites [PDF]

The role of somites and notochords in neuroectoderm differentiation from the embryonic ectoderm and its subsequent patterning into regional compartments along rostro-caudal and dorso-ventral axes, especially in humans, remains elusive.
سقا, محسن, رضوي, شهناز, صالحی, حسین, نصر اصفهاني, محمد حسين, کربلایی, خدیجه, نعمت الهی, مرضیه, بهاروند, حسين, تنهايي, سميه   +7 more
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Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state. [PDF]

, 2012
DNA methylation patterns change dynamically during mammalian development and lineage specification, yet scarce information is available about how DNA methylation affects gene expression profiles upon differentiation.
Spada, Fabio, Zacher, Benedikt, Leonhardt, Heinrich, Bultmann, Sebastian, Daniela Meilinger, Heinrich Leonhardt (18589), Daniela Meilinger (107843), Schmidt, Christine S., Benedikt Zacher, Fabio Spada (107869), Kerstin C Maier, Martin, Dietmar E., Christine S. Schmidt (107838), Heinrich Leonhardt, Christian Peter, Peter, Christian, Christine S Schmidt, Dietmar E. Martin (107866), Achim Tresch, Fabio Spada, Benedikt Zacher (107847), Maier, Kerstin C., Tresch, Achim, Christian Peter (107860), Meilinger, Daniela, Achim Tresch (107851), Kerstin C. Maier (107856), Dietmar E Martin, Sebastian Bultmann (107841), Sebastian Bultmann   +29 more
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Deriving bovine embryonic stem-like cells in defined conditions

, 2011
The first embryonic stem ES cell line was isolated from mouse in 1981 (Evans and Kaufman 1981; Martin1981). However, ESCs are only available in rodent species.
Muhammad Alahdal, Hadil, Hadil Muhammad Alahdal   +1 more
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"Properties of Vibrissa follicle cells during follicle development and regeneration, and their interactions with embryonic stem cells." [PDF]

, 2001
Follicular dermal cells possess properties that regulate induction of follicle formation, hair growth, and follicle end bulb regeneration after amputation.
Harris, Susan Jane
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Isolation and characterisation of mouse amniotic fluid stem cells: study of their origin, regenerative potential and reprogramming into pluripotent cells [PDF]

, 2013
Introduction: Stem cells are defined by their ability to proliferate for a long period of time, a property known as ‘self-renewal’, and to give rise to differentiated cells.
Bertin, Enrica
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