Results 31 to 40 of about 354,563 (218)

Embryonic stem cell proteomics

Expert Review of Proteomics, 2006
Human embryonic stem cells potentially represent an unlimited source of cells and tissues for regenerative medicine. Understanding signaling events that drive proliferation and specialization of these cells into various differentiated derivatives is of utmost importance for controlling their behavior in vitro. Major progress has been made in unraveling
van Hoof, D., Mummery, C.L., Heck, A.J.R., Krijgsveld, J.   +3 more
openaire   +4 more sources

Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells.

, 2013
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T., Biology of Reproductive Cells, Pirity, M., Rungarunlert, Sasitorn, Klincumhom, Nuttha, Rungarunlert, S., Dinnyés, András, Tharasanit, Theerawat, Dep Gezondheidszorg Landbouwhuisdieren, Klincumhom, N., Techakumphu, M., Pirity, Melinda, Dinnyes, A.   +12 more
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Generation of three human induced pluripotent stem cell (hiPSC) lines derived from one Gaucher disease patient with Parkinson's disease and two unrelated Parkinson's disease patients with GBA mutations

Stem Cell Research, 2019
We describe the generation and characterization of hiPSC lines of one type 1-Gaucher disease patient with Parkinson's disease and two unrelated Parkinson's disease patients heterozygous for GBA mutations.
Fabiano A. Tofoli, Hsin Fen Chien, Egberto Reis Barbosa, Lygia V. Pereira   +3 more
doaj   +1 more source

Generation of 5 hiPSC lines derived from three unrelated idiopathic Parkinson disease patients and two unrelated healthy control individuals

Stem Cell Research, 2019
We describe generation of human induced pluripotent stem cell (hiPSC) lines of three unrelated idiopathic late onset Parkinson disease patients and two healthy controls above 60 years of age without neurological diseases nor Ashkenazi ancestry.
Fabiano de Araújo Tofoli, Hsin Fen Chien, Egberto Reis Barbosa, Lygia V. Pereira   +3 more
doaj   +1 more source

CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes [PDF]

, 2014
Standard culture of human induced pluripotent stem cells (hiPSCs) requires basic Fibroblast Growth Factor (bFGF) to maintain the pluripotent state, whereas hiPSC more closely resemble epiblast stem cells than true naïve state ES which requires LIF to ...
Tang, D, Suzuki, H., Forrest, Alistair R. R., Hasegawa, Y., Suzuki, H, Ovchinnikov, Dmitry A., Hitchens, Kelly J., Takahashi, N., Forrest, A.R.R., Kenna, Tony, Suzuki, Harukazu, Tang, D., Joshi, Anagha, Hayashizaki, Y., Wolvetang, Ernst, Tang, Dave, Suzuki, H., Forrest, Alistair R R, FANTOM Consortium, the FANTOM consortium, Vijayan, Dipti, Wells, Christine A., Hasegawa, Y, Hayashizaki, Yoshihide, Forrest, ARR, Takahashi, Naoko, Briggs, James, Hasegawa, Yuki, Blumenthal, Antje, Tang, D., Hayashizaki, Y, ?, ?, Sajantila, Antti, Hasegawa, Y., Takahashi, N, Takahashi, N., Forrest, A. R., Beckhouse, Anthony G., FANTOM Consortium,, Hayashizaki, Y.   +39 more
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Introducing embryonic stem cells [PDF]

Current Biology, 2001
The editors of Current Biology welcome correspondence on any article in the journal, but reserve the right to reduce the length of any letter to be published. All Correspondence containing data or scientific argument will be refereed. Items for publication should either be submitted typed, double-spaced to: The Editor, Current Biology, Elsevier Science
openaire   +2 more sources

A Sweet Potion to Put Embryonic Stem Cells to Sleep

The Scientific World Journal, 2009
Human embryonic stem cells (hESCs) are rapidly revolutionizing the areas of drug screening and therapy. In view of their applications and high operational costs at global multicentric setups, the ability to store and transport hESCs and derivatives under
Kaushik D. Deb
doaj   +1 more source

Embryonic and induced pluripotent stem cells: understanding, creating, and exploiting the nano-niche for regenerative medicine.

, 2013
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have the capacity to differentiate into any specialized cell type of the human body, and therefore, ESC/iPSC-derived cell types offer great potential for regenerative medicine ...
Kingham, Emma Jayne, Richard O.C. Oreffo, Oreffo, Richard O.C., Emmajayne Kingham   +3 more
core   +1 more source

NSUN2 relies on ALYREF to regulate Nrf2-mediated oxidative stress and alleviate Dox-induced liver injury

Biology Direct
Background Doxorubicin (Dox) is associated with various liver injuries, limiting its clinical utility. This study investigates whether NSUN2 participates in Dox-induced liver injury and the associated molecular mechanism.
Yingying Huang, Xiao Li, Lin Wei, Shinan Ma, Liming Ma, Yuxin Zan, Xiju He, Yijun Tang, Yan Ding   +8 more
doaj   +1 more source

Behind the developing brains and beating hearts of stem cell-derived embryo models

Open Biology, 2023
Studies over the past decade have shown how stem cells representing embryonic and extra-embryonic tissues of the mouse can self-assemble in the culture dish to recapitulate an astonishing part of early embryonic development.
Gianluca Amadei, David M. Glover
doaj   +1 more source