Results 221 to 230 of about 565,140 (354)

Protocol for differentiation of human embryonic stem cells into surface epithelium and functional keratinocytes. [PDF]

STAR Protoc
Liu J, Huang H, Ouyang H.
europepmc   +1 more source

Rapid Generation of Stable Transgenic Embryonic Stem Cell Lines Using Modular Lentivectors

, 2005
David M. Suter, Laetitia Cartier, Esther Bettiol, Diderik Tirefort, Marisa Jaconi, Michel Dubois‐Dauphin, Karl‐Heinz Krause   +6 more
openalex   +2 more sources

Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma

Advanced Science, EarlyView.
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, Jason T. Huse, Bo Chen, Timothy A. Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang   +16 more
wiley   +1 more source

Corrigendum: ANGPTL8 promotes adipogenic differentiation of mesenchymal stem cells: potential role in ectopic lipid deposition

Frontiers in Endocrinology
Jian Tang, Jian Tang, Shinan Ma, Yujiu Gao, Fan Zeng, Ying Feng, Chong Guo, Lin Hu, Lingling Yang, Lingling Yang, Yanghui Chen, Qiufang Zhang, Yahong Yuan, Xingrong Guo, Xingrong Guo   +14 more
doaj   +1 more source

Enhanced differentiation capacity of parthenogenetic embryonic stem cells via incorporation of non-growing oocyte genomes in mouse. [PDF]

Am J Stem Cells
Shao H, Cao J, Lu R.
europepmc   +1 more source

Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells [PDF]

, 2004
Sebastian Carotta, Sandra Pilat, Andreas Mairhofer, Uwe Schmidt, Helmut Dolznig, Peter Steinlein, Hartmut Beug   +6 more
openalex   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Production of live monkeys and their genetically matched embryonic stem cells from single embryos. [PDF]

Nat Commun
Si C, Zhu R, Wu J, Chen Z, Tang Z, Li Z, Kang Y, Xiang L, Zuo J, Yang P, Chu C, Yang S, Li Z, Zhao L, Chen X, Pu Y, Tian B, Yang Z, Ji W, Dai S, Niu Y.   +20 more
europepmc   +1 more source

Human Embryonic-like ECM (hECM) Stimulates Proliferation and Differentiation in Stem Cells While Killing Cancer Cells

, 2011
Emmett Pinney, Michael Zimber, Aaron Schenone, Mayra Montes-Camacho, Frank Ziegler, Gail K. Naughton   +5 more
openalex   +2 more sources

Single‐Nucleus RNA Sequencing Reveals Mid‐Gestational Neurodevelopment Features in the Superior Temporal Plane from Fetuses with Nonsyndromic Cleft Lip and Palate

Advanced Science, EarlyView.
Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong, Xin‐Wei Huang, Qiu‐Xia Xiao, Ying‐Gang Zheng, Hao‐Yue Qin, Chang‐Le Fang, Li Chen, Ruo‐Lan Du, Qiu‐Lin Wang, Li‐Ren Huangfu, Ye‐Qing Fei, Yang‐Yang Zhao, Chen‐Yang Zhai, Ze‐Mian Chen, Shi‐Kun Yuan, Yu‐Ji Zhou, Xing‐Man He, Ting‐Ting Zhi, Xiao‐He Tian, Ting‐Hua Wang   +19 more
wiley   +1 more source