Results 251 to 260 of about 571,903 (350)

Derivation of embryonic stem cells across avian species [PDF]

Xi Chen, Zheng Guo, Xinyi Tong, Xizi Wang, Xugeng Liu, Hiroki Nagai, Ping Wu, Jiayi Lu, David Huss, Martin Tran, Carol Readhead, C.-S. Wu, Lin Cao, Yixin Huang, Zhao‐Chong Zeng, Fan Feng, Nima Adhami, Sirjan Mor, Rusty Lansford, Cheng‐Ming Chuong, Guojun Sheng, Carlos Lois, Qi-Long Ying   +22 more
openalex   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

Advanced Science, EarlyView.
ABSTRACT The cytosine (C) modifications 5‐methylcytosine (mC) and 5‐hydroxymethylcytosine (hmC) are central regulatory elements of mammalian genomes. Both marks occur in double‐stranded DNA in either strand‐symmetric or ‐asymmetric fashion, but it is still poorly understood how this symmetry information is selectively read out by the nuclear proteome ...
Lena Engelhard, Zeyneb Vildan Cakil, Marlon S. Zambrano‐Mila, Simone Eppmann, Tye Gonzalez, Rasmus Linser, Petra Janning, Sidney Becker, Daniel Summerer   +8 more
wiley   +1 more source

Enhanced differentiation capacity of parthenogenetic embryonic stem cells via incorporation of non-growing oocyte genomes in mouse. [PDF]

Am J Stem Cells
Shao H, Cao J, Lu R.
europepmc   +1 more source

Rapid Generation of Stable Transgenic Embryonic Stem Cell Lines Using Modular Lentivectors

, 2005
David M. Suter, Laetitia Cartier, Esther Bettiol, Diderik Tirefort, Marisa Jaconi, Michel Dubois‐Dauphin, Karl‐Heinz Krause   +6 more
openalex   +2 more sources

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Production of live monkeys and their genetically matched embryonic stem cells from single embryos. [PDF]

Nat Commun
Si C, Zhu R, Wu J, Chen Z, Tang Z, Li Z, Kang Y, Xiang L, Zuo J, Yang P, Chu C, Yang S, Li Z, Zhao L, Chen X, Pu Y, Tian B, Yang Z, Ji W, Dai S, Niu Y.   +20 more
europepmc   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

CHD7 regulates definitive endodermal and mesodermal development from human embryonic stem cells. [PDF]

Stem Cell Res Ther
Hu R, Zhao J, Lai KC, Wang S, Zheng J, Stoddard C, Lai L.   +6 more
europepmc   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Establishing Bovine Embryonic Stem Cells and Dissecting Their Self-Renewal Mechanisms. [PDF]

Int J Mol Sci
Li N, Yang Z, Su Y, Ma W, Zhao J, Wang X, Wan W, Xie S, Li H, Wang M, Zhao Y, Han S, Li T, Xiehe S, Guo J, Yue L, Li X, Wang A, Jiang F, Qing S, Liu X, Liu J, Lei A, Tang Y.   +23 more
europepmc   +1 more source