Evaluation of human umbilical cord blood as a source of embryonic stem cells [PDF]
Human umbilical cord blood (HUCB) has been poorly characterised as a source of embryonic stem cells (ESCs). The aim of this study, therefore, was to evaluate HUCB as source of mesenchymal stem cells (MSCs) with embryonic characteristics.
El-Sheemy, Mohamed+3 more
core +2 more sources
Stem cells in the embryonic kidney [PDF]
The mammalian kidney, the metanephros, is formed by a reciprocally inductive interaction between two precursor tissues, the metanephric mesenchyme and the ureteric bud. The ureteric bud induces the metanephric mesenchyme to differentiate into the epithelia of glomeruli and renal tubules.
openaire +3 more sources
Enhanced differentiation of human embryonic stem cells towards definitive endoderm on ultrahigh aspect ratio nanopillars [PDF]
Differentiation of human embryonic stem cells is widely studied as a potential unlimited source for cell replacement therapy to treat degenerative diseases such as diabetes.
Dufva, Martin+6 more
core +2 more sources
A Sweet Potion to Put Embryonic Stem Cells to Sleep
Human embryonic stem cells (hESCs) are rapidly revolutionizing the areas of drug screening and therapy. In view of their applications and high operational costs at global multicentric setups, the ability to store and transport hESCs and derivatives under
Kaushik D. Deb
doaj +1 more source
Behind the developing brains and beating hearts of stem cell-derived embryo models
Studies over the past decade have shown how stem cells representing embryonic and extra-embryonic tissues of the mouse can self-assemble in the culture dish to recapitulate an astonishing part of early embryonic development.
Gianluca Amadei, David M. Glover
doaj +1 more source
Effects of Alkaline Phosphatase, GATA, and BMP Expression on Three Populations of Cells: Spermatogonial Stem Cells, Embryonic Cells, and Embryonic Stem-Like Cells in Mice [PDF]
Background and Objective: Alkaline phosphatase, BMP, and GATA proteins are important factors in the process of spermatogenesis. This study aims to investigate the effect of alkaline phosphatase, GATA, and BMP expression on spermatogenic stem cells ...
Emad Reza, Hossein Azizi
doaj
Decatenation checkpoint deficiency in stem and progenitor cells [PDF]
SummaryThe decatenation checkpoint normally delays entry into mitosis until chromosomes have been disentangled through the action of topoisomerase II.
Bestor, Timothy H.+3 more
core +1 more source
Porcine pluripotent stem cells: progress, challenges and prospects [PDF]
Pluripotent stem cells (PSCs) are characterized by their capacity for high self-renewal and multiple differentiation potential and include embryonic stem cells, embryonic germ cells and induced PSCs.
Jianyong HAN, Yi-Liang MIAO, Jinlian HUA, Yan LI, Xue ZHANG, Jilong ZHOU, Na LI, Ying ZHANG, Jinying ZHANG, Zhonghua LIU
doaj +1 more source
Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis. [PDF]
Adult stem cells grow poorly in vitro compared to embryonic stem cells, and in vivo stem cell maintenance and proliferation by tissue niches progressively deteriorates with age.
CONBOY, Irina M+6 more
core +3 more sources
ABI3BP promotes renal aging through Klotho-mediated ferroptosis
The aging process of the kidneys is accompanied with several structural diseases. Abnormal fiber formation disrupts the balance of kidney structure and function, causing to end-stage renal disease and subsequent renal failure.
Ren Ji+8 more
doaj +1 more source