Results 71 to 80 of about 506,868 (329)
FEBS Open Bio, EarlyView.ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu +6 more
wiley +1 more source
Immunosuppression by Embryonic Stem Cells [PDF]
Stem Cells, 2007 AbstractEmbryonic stem cells or their progeny inevitably differ genetically from those who might receive the cells as transplants. We tested the barriers to engraftment of embryonic stem cells and the mechanisms that determine those barriers. Using formation of teratomas as a measure of engraftment, we found that semiallogeneic and fully allogeneic ...
Cody A. Koch +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells
Cell & Bioscience, 2017 Increasing evidence indicates that embryonic stem cell specific microRNAs (miRNAs) play an essential role in the early development of embryo. Among them, the miR-290-295 cluster is the most highly expressed in the mouse embryonic stem cells and involved ...
Kai Yuan +4 more
doaj +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
PLoS ONE, 2014 This study assesses changes in activator and repressor modifications to histones associated with the core transcription factor genes most highly upregulated or downregulated in pancreatic β-cells relative to expression in an embryonic stem cell line ...
Jennifer C Y Wong +3 more
doaj +1 more source
, 2012 Embrionalne matične stanice se od ostalih stanica u tijelu razlikuju po dvije osnovne karakteristike: sposobnost samoobnavljanja i pluripotentnost, sposobnost da se iz nedifreneciranog stanja razviju u bilo koji tip stanice u tijelu.
Bačić, Mateja
core +2 more sources
Stem Cells from a Biological Perspective in Animals: A Review [PDF]
, 2017 Cells are the smallest living units of living system. Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide to produce more stem cells.
Jain, A. (Archana) +2 more
core +1 more source
Advanced Biology, EarlyView.The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua +5 more
wiley +1 more source
Journal of Translational Medicine, 2011 In mid November the biopharma industry was shocked by the announcement from Geron that they were ending work on embryonic stem cell research and therapy.
Ichim Thomas +2 more
doaj +1 more source