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Brief guidelines for zebrafish embryotoxicity tests. [PDF]
Mol CellsHong T, Park J, Song G, Lim W.
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Maternal Consumption of Nano-Ginger: Implications for Fetal Development and Organogenesis in Rat Models. [PDF]
Adv Biomed ResAlQayyim ZMH +3 more
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Locoweed Embryotoxicity in Rats
Clinical Toxicology, 1980In an effort to develop a laboratory animal assay for locoweed (Astragalus lentiginosus and Astragalus wootoni) teratogenicity, different amounts of the plant were administered either in feed pellets or by gavage to rats. In preliminary experiments with A.
B K, Nelson +3 more
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Validation of an Embryotoxicity Assay
American Journal of Reproductive Immunology, 1995PROBLEM: Culture of mouse blastocysts has served as a tool for identifying various embryotoxic factors in human serum. While inactivated, sera from recurrently aborting women inhibit mouse blastocyst development in vitro. Variation in results from individual serum samples has limited the usefulness of this assay in establishing a new classification of ...
R G, Roussev +4 more
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1980
No animal species exists with which the situation in man can be completely mimicked. This also holds true for non-human primates. With animal experiments only certain aspects of the whole complex situation can be analyzed. In order to achieve this successfully, animal species and experimental set-ups have to be chosen carefully to represent the ...
R, Bass, D, Neubert
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No animal species exists with which the situation in man can be completely mimicked. This also holds true for non-human primates. With animal experiments only certain aspects of the whole complex situation can be analyzed. In order to achieve this successfully, animal species and experimental set-ups have to be chosen carefully to represent the ...
R, Bass, D, Neubert
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Embryotoxicity of Mirtazapine: A study using Chick Embryotoxicity Screening Test
Reproductive Toxicology, 2010Mirtazapine is a new antidepressant used in last years, however experience with it during pregnancy is unsatisfactory on the present. Its wide therapeutic range and only little proved side effects may be an advantage for treatment during pregnancy. Aim of our study was to contribute to the knowledge on possible risks.For embryotoxicity testing we used ...
Eva, Manakova +3 more
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Embryotoxicity of meglumine antimoniate in the rat
Reproductive Toxicology, 2001Meglumine antimoniate (MA) is a pentavalent antimonial (Sb(V)) drug used to treat leishmaniasis. Despite the fact that Sb(V) organic compounds have been used in clinical practice for more than 50 years, information on their safety during pregnancy is still scanty. This study was undertaken to evaluate the embryo/fetotoxicity of MA in the rat.
F J, Paumgartten, I, Chahoud
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Marihuana-Induced Embryotoxicity in the Rabbit
Toxicological Sciences, 1986Few teratogenic studies in animals have been performed simulating marihuana smoking in man. An inhalation marihuana teratology study was conducted in albino rabbits utilizing a modified automatic smoking machine originally developed for rats and mice. Appropriate numbers of dams were exposed to 4 puffs (0.14 mg/kg), 8 puffs (0.72 mg/kg), or 16 puffs (1.
H, Rosenkrantz +3 more
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American Journal of Obstetrics and Gynecology, 1977
Intraperitoneal injection of bilirubin in a dosage of 25 mg. per kilogram during the days nine to 15 of gestation in bile duct-ligated heterozygous Gunn rats was embryotoxic. Bile duct ligation per se had no gross observable effects on fetal development.
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Intraperitoneal injection of bilirubin in a dosage of 25 mg. per kilogram during the days nine to 15 of gestation in bile duct-ligated heterozygous Gunn rats was embryotoxic. Bile duct ligation per se had no gross observable effects on fetal development.
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