Results 81 to 90 of about 368 (238)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle   +11 more
wiley   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

A CLOSER LOOK AT THE ISSUES IN FIRST LANGUAGE ACQUISITION: NINE MAJOR ISSUES REVISITED [PDF]

open access: yesStudii si Cercetari Filologice: Seria Limbi Straine Aplicate, 2012
Concerning issues in first language acquisition, the present paper explores positions in theory- making, asyntacticity of early child language, Piaget's idea about children's logical thinking, Vygotsky's and Chomsky's controversy over the origins of ...
Lotfollah Karimi   +2 more
doaj  

Antologías emergentes

open access: yes, 1980
"Este Artículo pertenece a la sección Hic et nunc. "
openaire   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

Complexity – emergence – ecological cognition [PDF]

open access: yesAvant, 2012
The present article constitutes an attempt at a review of a few selected questions related to the complexity paradigm and its implications for research on cognition, especially within the so-called ecological approach framework. I propose several theses,
Maciej Dombrowski
doaj  

Mereological emergentism

open access: yes
The mereological problem known as the paradox of the heap raises fundamental questions about the nature of composition and emergence. This article reformulates the paradox in terms of neuroscience, arguing that if a single neuron does not constitute a brain and the incremental addition of neurons does not, in itself, create a brain, then no collection ...
openaire   +1 more source

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