Results 41 to 50 of about 4,236 (177)
Emerin—prelamin A interplay in human fibroblasts [PDF]
Biology of the Cell, 2009 Background information. Emerin is a nuclear envelope protein that contributes to nuclear architecture, chromatin structure, and gene expression through its interaction with various nuclear proteins. In particular, emerin is molecularly connected with the nuclear lamina, a protein meshwork composed of lamins and lamin‐binding proteins underlying the ...
Capanni C +9 more
openaire +3 more sources
Emerin intermolecular links to emerin and BAF
Journal of Cell Science, 2014 Emerin is a conserved nuclear membrane LEM-domain protein that binds lamins and BAF (barrier-to-integration factor; BANF1) as a component of nuclear lamina structure. We report an advance in understanding the molecular basis of emerin function: inter-molecular emerin-emerin association.
Jason M, Berk +6 more
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Cells, 2019 Emerin is an essential LEM (LAP2, Emerin, MAN1) domain protein in metazoans and an integral membrane protein associated with inner and outer nuclear membranes.
Magda Dubińska-Magiera +5 more
doaj +1 more source
Cells, 2020 LAP2-Emerin-MAN1 (LEM) domain-containing proteins represent an abundant group of inner nuclear membrane proteins involved in diverse nuclear functions, but their functional redundancies remain unclear.
Bernhard Moser +4 more
doaj +1 more source
Temporal Stretch-Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection. [PDF]
Adv Sci (Weinh)Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Shim HW +10 more
europepmc +2 more sources
Pathology and Oncology Research, 2022 Background: The nuclear laminar protein Lamin A and inner nuclear membrane protein Emerin plays important role in sustaining nuclear structure. However, They have not investigated the significance of these proteins for development of pancreatic ...
Tamaki Hiroe +8 more
doaj +1 more source
The nuclear envelope LEM-domain protein emerin [PDF]
Nucleus, 2013 Emerin, a conserved LEM-domain protein, is among the few nuclear membrane proteins for which extensive basic knowledge--biochemistry, partners, functions, localizations, posttranslational regulation, roles in development and links to human disease--is available.
Berk, Jason M +2 more
openaire +2 more sources
Investigating the Role of Emerin in Nuclear Envelope Budding and Muscular Disease [PDF]
, 2023 Nuclear envelope (NE) budding was first observed in the mid-20th century and has garnered more interest in recent years. Believed to follow a mechanism similar to herpes virus (HV) egress, the dynamics of this phenomenon have not been well documented in ...
Probst, Maxwell
core +4 more sources
Emerin anchors Msx1 and its protein partners at the nuclear periphery to inhibit myogenesis
Cell & Bioscience, 2019 Background Previous studies have shown that in myogenic precursors, the homeoprotein Msx1 and its protein partners, histone methyltransferases and repressive histone marks, tend to be enriched on target myogenic regulatory genes at the nuclear periphery.
Zhangjing Ma +8 more
doaj +1 more source
Cells, 2020 Emerin is one of the best characterized proteins of the inner nuclear membrane, but can also occur at the level of the endoplasmic reticulum. We now use enhanced ascorbate peroxidase 2 (APEX2) to probe the environment of emerin.
Marret Müller +4 more
doaj +1 more source