Results 51 to 60 of about 6,268 (192)
Expression of the Ebola Virus VP24 Protein Compromises the Integrity of the Nuclear Envelope and Induces a Laminopathy-Like Cellular Phenotype
mBio, 2021 Ebola virus (EBOV) VP24 protein is a nucleocapsid-associated protein that inhibits interferon (IFN) gene expression and counteracts the IFN-mediated antiviral response, preventing nuclear import of signal transducer and activator of transcription 1 ...Santiago Vidal, Maite Sánchez-Aparicio, Rocío Seoane, Ahmed El Motiam, Emily V. Nelson, Yanis H. Bouzaher, Maite Baz-Martínez, Isabel García-Dorival, Susana Gonzalo, Enrique Vázquez, Anxo Vidal, César Muñoz-Fontela, Adolfo García-Sastre, Carmen Rivas +13 moredoaj +1 more sourceNuclear actin and myosins in adenovirus infection [PDF]
, 2015 Adenovirus serotypes have been shown to cause drastic changes in nuclear organization, including the transcription machinery, during infection. This ability of adenovirus to subvert transcription in the host cell facilitates viral replication.De Lanerolle, Primal, Fuchsova, Beata, Serebryannyy, Leonid A. +2 morecore +1 more sourceA De Novo Sequence Variant in Barrier-to-Autointegration Factor Is Associated with Dominant Motor Neuronopathy
Cells, 2023 Barrier-to-autointegration factor (BAF) is an essential component of the nuclear lamina. Encoded by BANF1, this DNA binding protein contributes to the regulation of gene expression, cell cycle progression, and nuclear integrity.Agathe Marcelot, Felipe Rodriguez-Tirado, Philippe Cuniasse, Mei-ling Joiner, Simona Miron, Alexey A. Soshnev, Mimi Fang, Miles A. Pufall, Katherine D. Mathews, Steven A. Moore, Sophie Zinn-Justin, Pamela K. Geyer +11 moredoaj +1 more sourceNestor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation [PDF]
, 2014 Background - Premature aging syndromes recapitulate many aspects of natural aging and provide an insight into this phenomenon at a molecular and cellular level.Ashton, Nicholas W., Bolderson, Emma, Box, Joseph K., Croft, Laura V., O'Byrne, Kenneth J., Paquet, Nicolas, Richard, Derek J., Suraweera, Amila, Urquhart, Aaron J., Zhang, Shu-Dong +9 morecore +3 more sourcesLimb-Girdle Muscular Dystrophy Due to Emerin Gene Mutations [PDF]
Archives of Neurology, 2007 Emery-Dreifuss muscular dystrophy, caused by EMD gene mutations, is characterized by humeroperoneal muscular dystrophy, joint contractures, and conduction defects and is often associated with sudden cardiac death, even without prior cardiac symptoms.To describe the clinical and molecular features of 2 patients with limb-girdle muscular dystrophy with ...Shigehisa, Ura, Yukiko K, Hayashi, Kanako, Goto, Mina Nolasco, Astejada, Terumi, Murakami, Masako, Nagato, Shigeru, Ohta, Yasuhisa, Daimon, Hidehiro, Takekawa, Koichi, Hirata, Ikuya, Nonaka, Satoru, Noguchi, Ichizo, Nishino +12 moreopenaire +2 more sourcesThe Molecular Basis and Biologic Significance of the β-Dystroglycan-Emerin Interaction [PDF]
International Journal of Molecular Sciences, 2020 β-dystroglycan (β-DG) assembles with lamins A/C and B1 and emerin at the nuclear envelope (NE) to maintain proper nuclear architecture and function. To provide insight into the nuclear function of β-DG, we characterized the interaction between β-DG and emerin at the molecular level. Emerin is a major NE protein that regulates multiple nuclear processes Gómez-Monsivais, Wendy Lilián, Monterrubio-Ledezma, Feliciano, Huerta-Cantillo, Jazmin, Mondragon-Gonzalez, Ricardo, Alamillo-Iniesta, Alma, García-Aguirre, Ian, Azuara-Medina, Paulina Margarita, Arguello-García, Raúl, Rivera-Monroy, Jhon Erick, Holaska, James M., Hernández-Méndez, Jesús Mauricio Ernesto, Garrido, Efraín, Magaña, Jonathan Javier, Winder, Steve J., Brancaccio, Andrea, Martínez-Vieyra, Ivette, Navarro-Garcia, Fernando, Cisneros, Bulmaro, Gómez-Monsivais, Wendy Lilián; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, wlgomez@cinvestav.mx, Monterrubio-Ledezma, Feliciano; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, eduardo.monterrubio@cinvestav.mx, Huerta-Cantillo, Jazmin; Cell Biology Department, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, jazmin.huerta@cinvestav.mx, Mondragon-Gonzalez, Ricardo; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, rmondragon90@gmail.com, Alamillo-Iniesta, Alma; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, aalamilloi@cinvestav.mx, García-Aguirre, Ian; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, ian.garcia@cinvestav.mx, Azuara-Medina, Paulina Margarita; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, pauazmd@gmail.com, Arguello-García, Raúl; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, rag@cinvestav.mx, Rivera-Monroy, Jhon Erick; Department of Molecular Biology, Faculty of Medicine, GZMB, Georg-August University, 37073 Göttingen, Germany, jhonriv@gmail.com Laboratorio Instrumental de Alta Complejidad, Universidad de La Salle, 111311 Bogotá, Colombia, jhonriv@gmail.com, Holaska, James M.; Department of Biomedical Sciences, Cooper Medical School of Rowan University, 401 S Broadway, Camden, NJ 08028, USA, holaska@rowan.edu, Hernández-Méndez, Jesús Mauricio Ernesto; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, mauriciohermen91@hotmail.com, Garrido, Efraín; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, egarrido@cinvestav.mx, Magaña, Jonathan Javier; Laboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute-Luis Guillermo Ibarra Ibarra (INR-LGII), 14389 Mexico City, Mexico, magana.jj@tec.mx Departamento de Bioingeniería, Escuela de Ingeniería y Ciencias, Instituto Tecnológico y de Estudios Superiores de Monterrey-Campus Ciudad de México, 14380 Ciudad de México, Mexico, magana.jj@tec.mx, Winder, Steve J.; Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield S10 2TN, UK, s.winder@sheffield.ac.uk, Brancaccio, Andrea; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK, andrea.brancaccio@cnr.it Institute of Chemical Sciences and Technologies “Giulio Natta” (SCITEC), 00168 Roma, Italy, andrea.brancaccio@cnr.it, Martínez-Vieyra, Ivette; Laboratory of Hematobiology, Escuela Nacional de Medicina y Homeopatía, Instituto Politécnico Nacional, 07320 Ciudad de México, Mexico, ivette0381@yahoo.com.mx, Navarro-Garcia, Fernando; Cell Biology Department, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, enavarro@cinvestav.mx, Cisneros, Bulmaro; Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), 07360 Mexico City, Mexico, bcisnero@cinvestav.mx +35 moreopenaire +9 more sourcesEmerin expression in early development of Xenopus laevis
European Journal of Cell Biology, 2005 Emerin is an integral protein of the inner nuclear membrane in the majority of differentiated vertebrate cells. In humans, deficiency of emerin causes a progressive muscular dystrophy of the Emery-Dreifuss type. The physiological role of emerin is poorly understood.Martin, Gareiss, Kathrin, Eberhardt, Eleonora, Krüger, Sebastian, Kandert, Carolin, Böhm, Hanswalter, Zentgraf, Clemens R, Müller, Marie-Christine, Dabauvalle +7 moreopenaire +2 more sourcesResetting a functional G1 nucleus after mitosis [PDF]
, 2016 © The Author(s) 2015. The maintenance of the correct cellular information goes beyond the simple transmission of an intact genetic code from one generation to the next. Epigenetic changes, topological cues and correct protein-protein interactions need to De Castro, IJ, Gokhan, E, Vagnarelli, Pcore +2 more sources
