Results 61 to 70 of about 6,268 (192)
Barrier-to-Autointegration Factor Phosphorylation on Ser-4 Regulates Emerin Binding to Lamin A In Vitro and Emerin Localization In Vivo [PDF]
Molecular Biology of the Cell, 2006 Barrier-to-autointegration factor (BAF) is a conserved 10-kDa chromatin protein essential in proliferating cells. BAF dimers bind double-stranded DNA, histone H3, histone H1.1, lamin A, and transcription regulators, plus emerin and other LEM-domain nuclear proteins.
Luiza, Bengtsson, Katherine L, Wilson
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2019 Emerin (EMD) and barrier to autointegration factor 1 (BANF1) each bind A-type lamins (LMNA) as fundamental components of nuclear lamina structure. Mutations in LMNA, EMD and BANF1 are genetically linked to many tissue-specific disorders including Emery ...
Tejas Dharmaraj +5 more
doaj +1 more source
Cell Mechanosensitivity to Extremely Low Magnitude Signals is Enabled by a LINCed Nucleus [PDF]
, 2015 A cell's ability to recognize and adapt to the physical environment is central to its survival and function, but how mechanical cues are perceived and transduced into intracellular signals remains unclear. In mesenchymal stem cells (MSCs), high-magnitude
Bas, Guniz +11 more
core +1 more source
Cytoskeleton, EarlyView.ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves +3 more
wiley +1 more source
The Nuclear Envelope Lamina Network Has Elasticity and a Compressibility Limit Suggestive of a Molecular Shock Absorber [PDF]
, 2004 Author Posting © Journal of Cell Science, 2004. This article is posted here by permission of Journal of Cell Science for personal use, not for redistribution.
Kahn, Samuel
core +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The effect of the presence of the BAF‐binding LEM‐domain and LaminA Ig‐fold on the stability of the BAF dimer was studied qualitatively using non‐equilibrium pull simulations and quantitatively through the calculation of the potential of mean force profile along BAF–BAF separation distance.
Aswin Vinod Muthachikavil +2 more
wiley +1 more source
Diffusion-driven self-assembly of emerin nanodomains at the nuclear envelope
Physical Review ResearchEmerin, a nuclear membrane protein with important biological roles in mechanotransduction and nuclear shape adaptation, self-assembles into nanometer-size domains at the inner nuclear membrane.
Carlos D. Alas +3 more
doaj +1 more source
Immunocytochemistry of nuclear domains and Emery-Dreifuss muscular dystrophy pathophysiology
European Journal of Histochemistry, 2009 The present review summarizes recent cytochemical findings on the functional organization of the nuclear domains, with a particular emphasis on the relation between nuclear envelope- associated proteins and chromatin.
NM Maraldi +8 more
doaj +1 more source
Annals of Clinical and Translational Neurology, 2021 Exome sequencing (ES) has revolutionized rare disease management, yet only ~25%–30% of patients receive a molecular diagnosis. A limiting factor is the quality of available phenotypic data.
Daniel G. Calame +16 more
doaj +1 more source
Distinct molecular signature of phospholamban p.Arg14del arrhythmogenic cardiomyopathy. [PDF]
, 2019 Phospholamban (PLN) p.Arg14del cardiomyopathy is characterized by a distinct arrhythmogenic biventricular phenotype that can be predominantly left ventricular, right ventricular, or both.
Asimaki, A +10 more
core +3 more sources