Revista Brasileira de Plantas Medicinais, 2009 Este estudo foi conduzido com 13 populações amostradas nos estados RJ, MG, ES e BA para a coleta de dados ecogeográficos da poaia (Psychotria ipecacuanha).
E.R. Martins +3 more
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PKC Inhibits Sec61 Translocon-Mediated Sarcoplasmic Reticulum Ca2+ Leak in Smooth Muscle Cells
Frontiers in Physiology, 2022 PKC inhibitors stimulate Ca2+ release from internal stores in diverse cell types. Our data indicate that this action cannot be explained by an increased agonist-induced IP3 production or an overloaded SR Ca2+ pool in smooth muscle cells from guinea pig ...
Adan Dagnino-Acosta +1 more
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Very Rare Complementation between Mitochondria Carrying Different Mitochondrial DNA Mutations Points to Intrinsic Genetic Autonomy of the Organelles in Cultured Human Cells [PDF]
, 2000 In the present work, a large scale investigation was done regarding the capacity of cultured human cell lines (carrying in homoplasmic form either the mitochondrial tRNALys A8344G mutation associated with the myoclonic epilepsy and ragged red fiber ...
Attardi, Giuseppe +3 more
core +1 more source
Identification of Potent EGFR Inhibitors from TCM Database@Taiwan [PDF]
, 2011 Overexpression of epidermal growth factor receptor (EGFR) has been associated with cancer. Targeted inhibition of the EGFR pathway has been shown to limit proliferation of cancerous cells.
AE Wakeling +61 more
core +3 more sources
Cell Discovery, 2018 The re-emergence of Zika virus (ZIKV) and Ebola virus (EBOV) poses serious and continued threats to the global public health. Effective therapeutics for these maladies is an unmet need.
Shu Yang +34 more
semanticscholar +1 more source
The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. [PDF]
StructureEiler DR +6 more
europepmc +3 more sources
The importance of Poly(ADP-Ribose) Polymerase as a sensor of unligated Okazaki fragments during DNA replication [PDF]
, 2018 Poly(ADP-ribose) is synthesized by PARP enzymes during the repair of stochastic DNA breaks. Surprisingly, however, we show that most if not all endogenous poly(ADP-ribose) is detected in normal S phase cells at sites of DNA replication. This S phase poly(
Caldecott, Keith W +5 more
core +1 more source
Informatics in Medicine Unlocked, 2022 Mucormycosis has become a global issue due to its potential to infect and destroy organs, as well as its high fatality rate. Co-infecting with Covid 19 or when infecting after Covid 19, it becomes more lethal.
Anik Banik +5 more
doaj +1 more source
Functional integrity of the retrosplenial cortex is essential for rapid consolidation and recall of fear memory [PDF]
, 2013 Memory storage is a temporally graded process involving different phases and different structures in the mammalian brain. Cortical plasticity is essential to store stable memories, but little is known regarding its involvement in memory processing.
Cammarota, Martin Pablo +4 more
core +3 more sources
The role of cyclin synthesis, modification and destruction in the control of cell division [PDF]
, 1989 This paper reviews our current knowledge of the cyclins based on observations of the oocytes and eggs of sea urchins, clams and frogs. Cyclins are proteins found in all eukaryotes whose special property is rapid destruction at specific stages in the cell
Blow, J. +9 more
core +2 more sources