Results 31 to 40 of about 6,696 (158)
Background Patients with lung adenocarcinoma (LUAD) may be more predisposed to coronavirus disease 2019 (COVID-19) and have a poorer prognosis. Currently, there is still a lack of effective anti-LUAD/COVID-19 drugs.
Kun Zhang +5 more
doaj +1 more source
Researches into the structure of emetine [PDF]
The first crude preparation of the alkaloid emetine was obtained in 1817 by Pelletier from the plant species Cephaelis ipecacuanha. Since that day many workers have turned their attentions to the structural problem presented by this alkaloid, among them ...
Battersby, Alan Rushton
core +2 more sources
Nature has given us yet another wild card in the form of Zika virus (ZIKV). It was found in 1947, but has only recently become an important public health risk, predominantly to pregnant women and their unborn offspring. Currently, no specific therapeutic
Nabeelah Bibi Sadeer +6 more
doaj +1 more source
Studies on some dehydrogenation products of emetine [PDF]
This thesis is concerned chiefly with the study of some dehydrogenation product obtained by mild oxidation of emetine. The primary aim was to obtain information about some of the dehydrogenation products of emetine which would permit elucidation of their
Williams, Jack A.
core +1 more source
Este estudo foi conduzido com 13 populações amostradas nos estados RJ, MG, ES e BA para a coleta de dados ecogeográficos da poaia (Psychotria ipecacuanha).
E.R. Martins +3 more
doaj +1 more source
Emetine and cephaeline content in plants of Psychotria ipecacuanha in Costa Rica
The objective of this study was to identify the emetic metabolites in different parts of the P. ipecacuanha, a plant with emetic properties. Partial phytochemical analysis was performed to determine the presence of emetine and cephaeline in leaves, stems
María Catalina Rosales López +2 more
doaj +1 more source
Retrograde axonal transport of rabies virus is unaffected by interferon treatment but blocked by emetine locally in axons. [PDF]
Neuroinvasive viruses, such as alpha herpesviruses (αHV) and rabies virus (RABV), initially infect peripheral tissues, followed by invasion of the innervating axon termini.
Margaret A MacGibeny +4 more
doaj +1 more source
PKC Inhibits Sec61 Translocon-Mediated Sarcoplasmic Reticulum Ca2+ Leak in Smooth Muscle Cells
PKC inhibitors stimulate Ca2+ release from internal stores in diverse cell types. Our data indicate that this action cannot be explained by an increased agonist-induced IP3 production or an overloaded SR Ca2+ pool in smooth muscle cells from guinea pig ...
Adan Dagnino-Acosta +1 more
doaj +1 more source
Transcriptional regulation of the multidrug resistance EhPgp5 gene in Entamoeba histolytica is induced by emetine stress. EhPgp5 overexpression alters the chloride-dependent currents that cause trophozoite swelling, diminishing induced programmed cell ...
Alma Nieto +4 more
doaj +1 more source
Spectrophotofluorometric Determination of Emetine in Animal Tissues
A simple rapid spectrophotofluorometric method for assaying emetine in animal tissues is described. Tissue emetine concentrations have been determined in rats at intervals up to 14 days after single doses of emetine hydrochloride or emetine bismuth ...
B Davis, E G Tomich, M G Dodds
core +1 more source

