Results 51 to 60 of about 6,696 (158)
Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine
Viruses are the major causes of acute and chronic infectious diseases in the world. According to the World Health Organization, there is an urgent need for better control of viral diseases.
Petter I. Andersen +14 more
doaj +1 more source
Effects of emetine on FOS mRNA synthesis and decay.
(A) Effects of emetine on FOS transcription. Healthy granulocytes were cultured in the presence of 0.5 mM ethynyl uridine (EU) for a total of 60 min with or without a p38 inhibitor SB203580, and after the initial 30 min, emetine was added.
Tsutomu Shichishima (402023) +8 more
core +1 more source
Trichothecene mycotoxins, potent translational inhibitors that are associated with human food poisonings and damp-building illnesses, are of considerable concern to animal and human health.
Wenda Wu +3 more
doaj +1 more source
Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations. [PDF]
The widespread introduction of artemisinin-based combination therapy has contributed to recent reductions in malaria mortality. Combination therapies have a range of advantages, including synergism, toxicity reduction, and delaying the onset of ...
Holly Matthews +4 more
doaj +1 more source
Anti-HCMV activity of emetine and synergy with GCV.
A) Cells were infected with pp28-luciferase HCMV Towne and treated with indicated concentrations of emetine or GCV. Luciferase activity was measured at 72 hpi.
Xin Hu (38924) +14 more
core +1 more source
Abstract Mycotoxins (mould toxins) are secondary metabolites of moulds. They are natural toxins whose occurrence in food and feed is undesirable but cannot be completely avoided. Mycotoxins may occur as contaminants in plant products and raw materials such as grains, nuts and almonds if they are infested with mould during cultivation, storage or ...
German Federal Institute for Risk Assessment (BfR)
wiley +1 more source
CalcuSyn output for the dihydroartemisin-emetine combination.
CalcuSyn output for the dihydroartemisin-emetine combination.
Jon Deakin (3813211) +4 more
core +1 more source
Transaminase and Norcoclaurine Synthase One‐Pot Cascades Towards (1S)‐Tetrahydroisoquinolines
A TAm‐NCS cascade towards THIQs has been established, starting from amines with the in situ production of aldehydes. The cascade was used with a variety of nonfunctionalized and functionalized amines, and reaction conditions modified to enhance formation of the desired cross‐products.
Jianxiong Zhao +5 more
wiley +1 more source
A short introduction illustrates the concept of chiral economical syntheses and the advantages of the corresponding approaches. Using the total synthesis of emetine according to the work of Openshaw and Whittaker and the total synthesis of the steroid ...
A. Fischli
doaj +1 more source
Activation of dopamine receptor D1 (D1R) stimulates PKA and ERK pathways via dissociation of stimulatory and olfactory G protein alpha subunits (Gαs/olf). PKA relieves striatal‐enriched protein tyrosine phosphatase (STEP) inhibition of ERK, promoting cyclic adenosine monophosphate response element‐binding protein (CREB)‐driven transcription of ...
Kevin Chua +2 more
wiley +1 more source

