Results 21 to 30 of about 5,579 (176)
Clinical efficacy of low-dose emetine for patients with COVID-19: a real-world study
Journal of Bio-X Research, 2021 . Objective:. Emetine, an isoquinoline alkaloid that is enriched at high concentrations in the lung, has shown potent in vitro activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Song Fan +36 more
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INHIBITION OF REDD1 EXPRESSION FOR THE REDUCTION OF GLUCOCORTICOID-INDUCED SIDE EFFECTS
Сибирский онкологический журнал, 2020 Glucocorticoids (GC ) have been an integral component of the treatment of leukemias and lymphomas for several decades. Specific cytotoxic effect of GC on transformed lymphoblasts mediates their use at the stage of the remission induction as well as ...
E. S. Lylova +6 more
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In Silico Studies of Bioactive Compounds Selected from Four African Plants with Inhibitory Activity Against Plasmodium falciparum Dihydrofolate Reductase-Thymidylate Synthase (pfDHFR-TS) [PDF]
Journal of Advanced Pharmacy Research, 2022 Objective: This present study aims to assess in silico inhibitory potentials of bioactive compounds present in Vernonia amygdalina (Bitter leaf), Cymbopogon citratus (Lemongrass), Azadirachta indica (Neem leaf), and Carica papaya (Pawpaw leaf) against ...
Ishola Akinwumi +4 more
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BMC Cancer, 2022 Background Patients with lung adenocarcinoma (LUAD) may be more predisposed to coronavirus disease 2019 (COVID-19) and have a poorer prognosis. Currently, there is still a lack of effective anti-LUAD/COVID-19 drugs.
Kun Zhang +5 more
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Journal of Infection and Public Health, 2023 Nature has given us yet another wild card in the form of Zika virus (ZIKV). It was found in 1947, but has only recently become an important public health risk, predominantly to pregnant women and their unborn offspring. Currently, no specific therapeutic
Nabeelah Bibi Sadeer +6 more
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Revista Brasileira de Plantas Medicinais, 2009 Este estudo foi conduzido com 13 populações amostradas nos estados RJ, MG, ES e BA para a coleta de dados ecogeográficos da poaia (Psychotria ipecacuanha).
E.R. Martins +3 more
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Emetine and cephaeline content in plants of Psychotria ipecacuanha in Costa Rica
Revista Colombiana de Química, 2020 The objective of this study was to identify the emetic metabolites in different parts of the P. ipecacuanha, a plant with emetic properties. Partial phytochemical analysis was performed to determine the presence of emetine and cephaeline in leaves, stems
María Catalina Rosales López +2 more
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Retrograde axonal transport of rabies virus is unaffected by interferon treatment but blocked by emetine locally in axons. [PDF]
PLoS Pathogens, 2018 Neuroinvasive viruses, such as alpha herpesviruses (αHV) and rabies virus (RABV), initially infect peripheral tissues, followed by invasion of the innervating axon termini.
Margaret A MacGibeny +4 more
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