Results 81 to 90 of about 13,374 (270)

The in vitro and in vivo testing of chemotherapeutic agents against pathogenic free living amebae : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University, Palmerston North, New Zealand. [PDF]

open access: yes, 1980
During the last ten years, there has been an increasing awareness of sporadic cases of Primary Amoebic Meningo-encephalitis (PAM) affecting primarily younger age groups and appearing in an acute fulminant form. The earliest positive case (Willaert, 1974)
Elmsly, Christopher John
core  

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Inhibitors of RNA and protein synthesis cause Glut4 translocation and increase glucose uptake in adipocytes

open access: yesScientific Reports, 2022
Insulin stimulates glucose uptake in adipocytes by triggering translocation of glucose transporter 4-containg vesicles to the plasma membrane. Under basal conditions, these vesicles (IRVs for insulin-responsive vesicles) are retained inside the cell via ...
A. B. Meriin   +3 more
doaj   +1 more source

New Diagnostic and Therapeutic Targets for Spinal Cord Injury: GRN Gene

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT Spinal cord injury (SCI) is a severe disabling disease due to the poor self‐healing of the central nervous system. Studies showed that many N6‐methyladenosine (m6A) RNA methylation profiles are hypomethylated after SCI, which are related to neural regeneration and different m6A marker genes.
Han Ding   +6 more
wiley   +1 more source

Chirale Ökonomie

open access: yesCHIMIA, 1976
A short introduction illustrates the concept of chiral economical syntheses and the advantages of the corresponding approaches. Using the total synthesis of emetine according to the work of Openshaw and Whittaker and the total synthesis of the steroid ...
A. Fischli
doaj   +1 more source

Drug repurposing approach against chikungunya virus: an in vitro and in silico study

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The chikungunya virus (CHIKV) is an alphavirus transmitted by Aedes mosquitoes. There are no licenced antivirals or vaccines for treatment or prevention. Drug repurposing approach has emerged as a novel concept to find alternative uses of therapeutics to
Bhagyashri Kasabe   +8 more
doaj   +1 more source

Canavanine Inhibits Vimentin Assembly But Not Its Synthesis in Chicken Embryo Erythroid Cells [PDF]

open access: yes, 1983
In chicken embryo erythroid cells, newly synthesized vimentin first enters a Triton X-100 (TX-100)-soluble pool and subsequently assembles posttranslationally into TX-100-insoluble vimentin filaments (Blikstad I., and E. Lazarides, J. Cell Biol., 96:1803-
Lazarides, Elias, Moon, Randall T.
core  

Tissue-specific Expression of Distinct Spectrin and Ankyrin Transcripts in Erythroid and Nonerythroid Cells [PDF]

open access: yes, 1985
cDNA probes for three components of the erythroid membrane skeleton, α spectrin, β spectrin, and ankyrin, were obtained by using monospecific antibodies to screen a λgt11 expression vector library containing cDNA prepared from chicken erythroid poly(A)^+
Lazarides, Elias   +3 more
core   +3 more sources

Identification of Novel Antiviral Compounds Targeting Entry of Hantaviruses

open access: yesViruses, 2021
Hemorrhagic fever viruses, among them orthohantaviruses, arenaviruses and filoviruses, are responsible for some of the most severe human diseases and represent a serious challenge for public health.
Jennifer Mayor   +3 more
doaj   +1 more source

Emetine and cephaeline production and regulation by in vitro propagation of Psychotria ipecacuanha (Brot.) Stokes in semi-solid media and temporary immersion bioreactor

open access: yes, 2020
Psychotria ipecacuanha, is a plant species with known medicinal properties that is critically endangered due to overexploitation of natural populations.
Simone Da Silva   +3 more
semanticscholar   +1 more source

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