Frontiers in Plant Science, 2022 In this work, the impact of terroir, cultivar, seasonality, and farming systems on functional traits of tomato was hierarchically investigated. Untargeted metabolomics, antioxidant capacity, colorimetric assays, and enzyme inhibition were determined. The
Gabriele Rocchetti +8 more
doaj +1 more source
Expression of the Mitochondrial Genome in HeLa Cells. XV. Effect of Inhibition of Mitochondrial Protein Synthesis on Mitochondrial Formation [PDF]
, 1973 The effect of selective inhibition of mitochondrial protein synthesis by chloramphenicol at 40 or 200 µg/ml on the formation of mitochondria in HeLa cells was investigated.
Attardi, Giuseppe, Storrie, Brian
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Targeting the Hippo/YAP Pathway: A Promising Approach for Cancer Therapy and Beyond
MedComm, Volume 6, Issue 9, September 2025.The potential of natural compounds to modulate the Hippo/YAP signaling pathway, a critical regulator of cell proliferation, differentiation, and survival, is explored. Dysregulation of this pathway is associated with various cancers, making it a target for therapeutic intervention.
Rajni Bala +13 more
wiley +1 more source
Identification of small molecules as novel anti-adipogenic compounds based on Connectivity Map
Frontiers in Endocrinology, 2022 Several physiological and pathological conditions such as aging, obesity, diabetes, anorexia nervosa are associated with increased adipogenesis in the bone marrow.
Shuang Zhang +5 more
doaj +1 more source
The site of synthesis of the iron-sulfur subunits of the flavoprotein and iron-protein fractions of human NADH dehydrogenase [PDF]
, 1988 The site of synthesis of the iron-sulfur subunits of the flavoprotein and iron-protein fractions of the human respiratory chain NADH dehydrogenase has been investigated to test the possibility that any of them is synthesized in mitochondria.
Attardi, Giuseppe +4 more
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Novel Synergistic Anti-Enteroviral Drug Combinations
Viruses, 2022 Background: Enterovirus infections affect people around the world, causing a range of illnesses, from mild fevers to severe, potentially fatal conditions. There are no approved treatments for enterovirus infections. Methods: We have tested our library of
Aleksandr Ianevski +7 more
doaj +1 more source
The in vitro and in vivo testing of chemotherapeutic agents against pathogenic free living amebae : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University, Palmerston North, New Zealand. [PDF]
, 1980 During the last ten years, there has been an increasing awareness of sporadic cases of Primary Amoebic Meningo-encephalitis (PAM) affecting primarily younger age groups and appearing in an acute fulminant form. The earliest positive case (Willaert, 1974)
Elmsly, Christopher John
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In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone
Drug Development Research, Volume 86, Issue 5, August 2025.ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Janine Aucamp +4 more
wiley +1 more source
European Journal of Medicinal Chemistry ReportsThe outbreak of COVID-19 pandemic caused by the infection of SARS-CoV-2, has become a global crisis, threatening public health and disrupting global economy.
Biswanath Dinda +5 more
doaj +1 more source
Toxicology Reports, 2015 Trichothecene mycotoxins, potent translational inhibitors that are associated with human food poisonings and damp-building illnesses, are of considerable concern to animal and human health.
Wenda Wu +3 more
doaj +1 more source