Results 11 to 20 of about 218,651 (379)

Spirometric assessment of emphysema presence and severity as measured by quantitative CT and CT-based radiomics in COPD

Respiratory Research, 2019
Background The mechanisms underlying airflow obstruction in COPD cannot be distinguished by standard spirometry. We ascertain whether mathematical modeling of airway biomechanical properties, as assessed from spirometry, could provide estimates of ...
Mariaelena Occhipinti, Matteo Paoletti, Brian J. Bartholmai, Srinivasan Rajagopalan, Ronald A. Karwoski, Cosimo Nardi, Riccardo Inchingolo, Anna R. Larici, Gianna Camiciottoli, Federico Lavorini, Stefano Colagrande, Vito Brusasco, Massimo Pistolesi   +12 more
doaj   +2 more sources

Association between Chest CT-defined Emphysema and Lung Cancer: A Systematic Review and Meta-Analysis.

Radiology, 2022
Background Given the different methods of assessing emphysema, controversy exists as to whether it is associated with lung cancer. Purpose To perform a systematic review and meta-analysis of the association between chest CT-defined emphysema and the ...
Xiaofei Yang, H. J. Wisselink, R. Vliegenthart, M. Heuvelmans, H. Groen, M. Vonder, M. Dorrius, G. D. de Bock   +7 more
semanticscholar   +1 more source

High-fiber diets attenuate emphysema development via modulation of gut microbiota and metabolism

Scientific Reports, 2021
Dietary fiber functions as a prebiotic to determine the gut microbe composition. The gut microbiota influences the metabolic functions and immune responses in human health.
Yoon Ok Jang, Ock-Hwa Kim, S. Kim, Se Hee Lee, Sunmi Yun, Se Eun Lim, H. Yoo, Yong Shin, S. Lee   +8 more
semanticscholar   +1 more source

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

Mediastinal Emphysema, Giant Bulla, and Pneumothorax Developed during the Course of COVID-19 Pneumonia

Korean Journal of Radiology, 2020
The coronavirus disease 2019 (COVID-19) pneumonia is a recent outbreak in mainland China and has rapidly spread to multiple countries worldwide. Pulmonary parenchymal opacities are often observed during chest radiography.
Ruihong Sun, Hongyuan Liu, Xiang Wang
semanticscholar   +1 more source

Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.

American Journal of Respiratory and Critical Care Medicine, 2021
INTRODUCTION Cigarette smoke (CS) inhalation triggers oxidative stress and inflammation, leading to accelerated lung aging, apoptosis, emphysema, and systemic pathologies.
F. Polverino, T. Wu, J. Rojas-Quintero, Xiaoyun Wang, Jonathan J. Mayo, M. Tomchaney, J. Tram, Samuel E Packard, Duo Zhang, Kristan H Cleveland, E. Córdoba-Lanús, C. Owen, A. Fawzy, G. Kinney, C. Hersh, N. Hansel, Kevin Doubleday, M. Sauler, Y. Tesfaigzi, J. Ledford, C. Casanova, J. Zmijewski, J. Konhilas, P. Langlais, R. Schnellmann, I. Rahman, M. McCormack, B. Celli   +27 more
semanticscholar   +1 more source

Reversal of emphysema by restoration of pulmonary endothelial cells

Journal of Experimental Medicine, 2021
We tested the role of endothelial dysfunction in the development of COPD/emphysema. We found that restoration of lung endothelial cells and blockade of endothelial-derived leucine-rich α-2-glycoprotein perturbs the pathogenesis of COPD/emphysema.
S. Hisata, A. Racanelli, P. Kermani, Ryan Schreiner, S. Houghton, Brisa Palikuqi, Balvir Kunar, Aiyuan Zhou, K. McConn, Allyson Capili, D. Redmond, D. Nolan, Michael Ginsberg, B. Ding, F. Martinez, J. Scandura, S. Cloonan, S. Rafii, A. Choi   +18 more
semanticscholar   +1 more source

COVID-19 with spontaneous pneumothorax,pneumomediastinum and subcutaneous emphysema

Journal of Travel Medicine, 2020
Highlight We present a case of COVID-19 pneumonia associated with spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema.
Weiyi Wang, R. Gao, Yulu Zheng, Libin Jiang   +3 more
semanticscholar   +1 more source

Pneumomediastinum and subcutaneous emphysema in COVID-19: barotrauma or lung frailty?

ERJ Open Research, 2020
Background In mechanically ventilated acute respiratory distress syndrome (ARDS) patients infected with the novel coronavirus disease (COVID-19), we frequently recognised the development of pneumomediastinum and/or subcutaneous emphysema despite ...
D. Lemmers, M. Abu Hilal, C. Bnà, Chiara Prezioso, E. Cavallo, Niccolò Nencini, S. Crisci, F. Fusina, G. Natalini   +8 more
semanticscholar   +1 more source

Automatic Emphysema Detection using Weakly Labeled HRCT Lung Images [PDF]

, 2018
A method for automatically quantifying emphysema regions using High-Resolution Computed Tomography (HRCT) scans of patients with chronic obstructive pulmonary disease (COPD) that does not require manually annotated scans for training is presented.
Carl, Jesper, Cheplygina, Veronika, de Bruijne, Marleen, Paschaloudi, Sofia, Peña, Isabel Pino, Vuust, Morten, Weinreich, Ulla Møller, Østergaard, Lasse Riis   +7 more
core   +7 more sources