Results 11 to 20 of about 213,364 (422)
Korean Journal of Radiology, 2020 The coronavirus disease 2019 (COVID-19) pneumonia is a recent outbreak in mainland China and has rapidly spread to multiple countries worldwide. Pulmonary parenchymal opacities are often observed during chest radiography.
Ruihong Sun, Hongyuan Liu, Xiang Wang
semanticscholar +1 more source
Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.
American Journal of Respiratory and Critical Care Medicine, 2021 INTRODUCTION Cigarette smoke (CS) inhalation triggers oxidative stress and inflammation, leading to accelerated lung aging, apoptosis, emphysema, and systemic pathologies.
F. Polverino +27 more
semanticscholar +1 more source
Reversal of emphysema by restoration of pulmonary endothelial cells
Journal of Experimental Medicine, 2021 We tested the role of endothelial dysfunction in the development of COPD/emphysema. We found that restoration of lung endothelial cells and blockade of endothelial-derived leucine-rich α-2-glycoprotein perturbs the pathogenesis of COPD/emphysema.
S. Hisata +18 more
semanticscholar +1 more source
Cancer Reports, EarlyView., 2023 Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada +16 more
wiley +1 more source
Optimizing Convolutional Neural Networks for Chronic Obstructive Pulmonary Disease Detection in Clinical Computed Tomography Imaging [PDF]
Comput Biol Med 185, 109533 (2025), 2023 We aim to optimize the binary detection of Chronic Obstructive Pulmonary Disease (COPD) based on emphysema presence in the lung with convolutional neural networks (CNN) by exploring manually adjusted versus automated window-setting optimization (WSO) on computed tomography (CT) images.
arxiv +1 more source
Clinical Pharmacology in Drug Development, Volume 12, Issue 1, Page 30-37, January 2023., 2023 Abstract The bioequivalence of a generic fudosteine tablet vs a brand‐named fudosteine tablet under fasting and fed conditions was evaluated in this study. This randomized, open‐label, single‐dose, 4‐way replicate, crossover, bioequivalence study included 64 healthy Chinese subjects (fasting cohort, n = 32; fed cohort, n = 32) who were assigned to ...
Mingxue Zhu +6 more
wiley +1 more source
COVID-19 with spontaneous pneumothorax,pneumomediastinum and subcutaneous emphysema
Journal of Travel Medicine, 2020 Highlight We present a case of COVID-19 pneumonia associated with spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema.
Weiyi Wang +3 more
semanticscholar +1 more source
Respiratory Research, 2020 The role of the ATP binding cassette transporter A1 (ABCA1) in maintaining cellular lipid homeostasis in cardiovascular disease is well established. More recently, the important beneficial role played by ABCA1 in modulating pathogenic disease mechanisms,
Patrick He +2 more
doaj +1 more source
Pneumomediastinum and subcutaneous emphysema in COVID-19: barotrauma or lung frailty?
ERJ Open Research, 2020 Background In mechanically ventilated acute respiratory distress syndrome (ARDS) patients infected with the novel coronavirus disease (COVID-19), we frequently recognised the development of pneumomediastinum and/or subcutaneous emphysema despite ...
D. Lemmers +8 more
semanticscholar +1 more source